Update on pathogenesis and diagnosis of intravascular catheter-related infections | Enfermedades Infecciosas y Microbiología Clínica

Article information

Resumen

Las infecciones asociadas al uso de catéteres intravasculares producen una importante mortalidad y morbilidad. El avance en los conocimientos de la patogenia de las bacteriemias asociadas a su uso nos permitirá desarrollar estrategias adecuadas para su cuidado y prevención. El propósito de esta revisión es destacar los aspectos más relevantes publicados en la literatura científica sobre la patogenia y diagnóstico de las infecciones asociadas a catéteres intravasculares, desarrollando 4 aspectos de interés: a) la patogenia de las infecciones asociadas a catéteres intravasculares; b) la patogenia de estas infecciones producidas por Staphylococcus lugdunensis; c) las novedades en el diagnóstico microbiológico de estas infecciones, y d) el uso de hemocultivos en la era de los sistemas de monitorización continua de éstos.

Palabras clave:

Catéter intravascular

Biopelícula

Hemocultivo

Staphylococcus

Abstract

Infections associated with the use of intravascular catheters cause a substantial morbidity and mortality. New knowledge in the pathogenesis of catheter related bloodstream infections has led to advances in the prevention and management of these infections. The purpose of the present chapter is to review the most relevant data published recently on pathogenesis and diagnosis of intravascular catheter-related infections. It is focus in four different aspects: a) pathogenesis of catheter-related infections and particularly factors affecting biofilm formation and modulation; b) pathogenesis of intravascular catheter-related infections caused by Staphylococcus lugdunensis; c) news on microbiological diagnosis of catheter-related bacteremia; and d) evaluation of current use of blood cultures in the era of continuous monitoring blood cultures systems.

Keywords:

Intravascular catheter

Biofilm

Blood culture

Staphylococcus

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