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Vol. 29. Núm. S4.
Update on infectious diseases
Páginas 16-21 (marzo 2011)
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Vol. 29. Núm. S4.
Update on infectious diseases
Páginas 16-21 (marzo 2011)
Acceso a texto completo
Update on pathogenesis and diagnosis of intravascular catheter-related infections
Actualización en la patogénesis y el diagnóstico de las infecciones relacionadas con el uso de catéteres intravasculares
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4987
Álvaro Pascuala,
Autor para correspondencia
apascual@us.es

Correspondence author.
, Emilia Cercenadob, Miguel Salavertc, José Elías García-Sánchezd, José María Eirose, Josefina Liñaresf, Cristina Fernándezg, Jordi Vilah
a Departamento de Microbiología, Hospital Universitario Virgen Macarena, Facultad de Medicina, Sevilla, Spain
b Servicio de Microbiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain
c Servicio de Enfermedades Infecciosas, Hospital La Fe, Valencia, Spain
d Servicio de Microbiología, Hospital Clínico, Salamanca, Spain
e Servicio de Microbiología, Hospital Clínico Universitario, Valladolid, Spain
f Servicio de Microbiología, Hospital de Bellvitge, Barcelona, Spain
g Servicio de Medicina Preventiva, Hospital Clínico San Carlos, Madrid, Spain
h Servicio de Microbiología, Hospital Clínic, Barcelona, Spain
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Resumen

Las infecciones asociadas al uso de catéteres intravasculares producen una importante mortalidad y morbilidad. El avance en los conocimientos de la patogenia de las bacteriemias asociadas a su uso nos permitirá desarrollar estrategias adecuadas para su cuidado y prevención. El propósito de esta revisión es destacar los aspectos más relevantes publicados en la literatura científica sobre la patogenia y diagnóstico de las infecciones asociadas a catéteres intravasculares, desarrollando 4 aspectos de interés: a) la patogenia de las infecciones asociadas a catéteres intravasculares; b) la patogenia de estas infecciones producidas por Staphylococcus lugdunensis; c) las novedades en el diagnóstico microbiológico de estas infecciones, y d) el uso de hemocultivos en la era de los sistemas de monitorización continua de éstos.

Palabras clave:
Catéter intravascular
Biopelícula
Hemocultivo
Staphylococcus
Abstract

Infections associated with the use of intravascular catheters cause a substantial morbidity and mortality. New knowledge in the pathogenesis of catheter related bloodstream infections has led to advances in the prevention and management of these infections. The purpose of the present chapter is to review the most relevant data published recently on pathogenesis and diagnosis of intravascular catheter-related infections. It is focus in four different aspects: a) pathogenesis of catheter-related infections and particularly factors affecting biofilm formation and modulation; b) pathogenesis of intravascular catheter-related infections caused by Staphylococcus lugdunensis; c) news on microbiological diagnosis of catheter-related bacteremia; and d) evaluation of current use of blood cultures in the era of continuous monitoring blood cultures systems.

Keywords:
Intravascular catheter
Biofilm
Blood culture
Staphylococcus
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Copyright © 2011. Elsevier España S.L.. All rights reserved
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