was read the article
array:23 [ "pii" => "S2529993X23002526" "issn" => "2529993X" "doi" => "10.1016/j.eimce.2023.06.007" "estado" => "S300" "fechaPublicacion" => "2024-02-01" "aid" => "2731" "copyright" => "Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica" "copyrightAnyo" => "2023" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Enferm Infecc Microbiol Clin. 2024;42:108-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:17 [ "pii" => "S2529993X23002642" "issn" => "2529993X" "doi" => "10.1016/j.eimce.2023.11.003" "estado" => "S300" "fechaPublicacion" => "2024-02-01" "aid" => "2738" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Enferm Infecc Microbiol Clin. 2024;42:110-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Diagnosis at first sight</span>" "titulo" => "Acute disseminated histoplasmosis with immune reconstitution syndrome after initiation of antiretroviral therapy in a patient with HIV" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "110" "paginaFinal" => "111" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Histoplasmosis diseminada aguda con síndrome de reconstitución inmunitaria tras el inicio de tratamiento antirretroviral en un paciente con VIH" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1268 "Ancho" => 1540 "Tamanyo" => 207304 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography angiography with presence of <span class="elsevierStyleItalic">bilateral diffuse</span> micronodular interstitial pattern.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ignacio Boira Enrique, Elisabet Delgado Sánchez, Violeta Esteban Ronda, Eusebi Chiner Vives" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ignacio" "apellidos" => "Boira Enrique" ] 1 => array:2 [ "nombre" => "Elisabet" "apellidos" => "Delgado Sánchez" ] 2 => array:2 [ "nombre" => "Violeta" "apellidos" => "Esteban Ronda" ] 3 => array:2 [ "nombre" => "Eusebi" "apellidos" => "Chiner Vives" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2529993X23002642?idApp=UINPBA00004N" "url" => "/2529993X/0000004200000002/v4_202403030727/S2529993X23002642/v4_202403030727/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2529993X23002502" "issn" => "2529993X" "doi" => "10.1016/j.eimce.2023.05.009" "estado" => "S300" "fechaPublicacion" => "2024-02-01" "aid" => "2726" "documento" => "article" "crossmark" => 1 "subdocumento" => "pgl" "cita" => "Enferm Infecc Microbiol Clin. 2024;42:102-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Consensus document</span>" "titulo" => "Executive summary of the consensus document on the shared care of patients with HIV infection between primary and hospital care" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "102" "paginaFinal" => "107" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Resumen ejecutivo del documento de consenso sobre el manejo compartido del paciente con infección por VIH entre Atención Primaria y Hospitalaria" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Javier Martínez-Sanz, Juan E. Losa-García, Nuria Orozco, Ignacio Alastrué, Juanjo Mascort, María Jesús Pérez-Elías" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Javier" "apellidos" => "Martínez-Sanz" ] 1 => array:2 [ "nombre" => "Juan E." "apellidos" => "Losa-García" ] 2 => array:2 [ "nombre" => "Nuria" "apellidos" => "Orozco" ] 3 => array:2 [ "nombre" => "Ignacio" "apellidos" => "Alastrué" ] 4 => array:2 [ "nombre" => "Juanjo" "apellidos" => "Mascort" ] 5 => array:2 [ "nombre" => "María Jesús" "apellidos" => "Pérez-Elías" ] 6 => array:1 [ "colaborador" => "Grupo de Trabajo de Atención Compartida en VIH (Sociedad Española de Medicina de Familia y Comunitaria – semFYC – y Grupo de estudio del SIDA de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica – GeSIDA SEIMC)" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0213005X23001726" "doi" => "10.1016/j.eimc.2023.05.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213005X23001726?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2529993X23002502?idApp=UINPBA00004N" "url" => "/2529993X/0000004200000002/v4_202403030727/S2529993X23002502/v4_202403030727/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Diagnosis at first sight</span>" "titulo" => "Catheter-related bacteremia of rare etiology" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "108" "paginaFinal" => "109" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ramón Vela-Fernández, Inmaculada Guerrero-Lozano, Manuel Rodriguez-Iglesias, Fátima Galán-Sánchez" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Ramón" "apellidos" => "Vela-Fernández" "email" => array:1 [ 0 => "ramon.vela.sspa@juntadeandalucia.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Inmaculada" "apellidos" => "Guerrero-Lozano" ] 2 => array:2 [ "nombre" => "Manuel" "apellidos" => "Rodriguez-Iglesias" ] 3 => array:2 [ "nombre" => "Fátima" "apellidos" => "Galán-Sánchez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Microbiología Clínica, Complejo Hospitalario Universitario Puerta del Mar-San Carlos, Cádiz, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Bacteriemia asociada a catéter de etiología infrecuente" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 646 "Ancho" => 1340 "Tamanyo" => 116384 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A) Bacterial growth (1 day), BD BBL™ Chocolate II Agar. (B) Gram stain from colonies, Gram-positive coccobacilli.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case description</span><p id="par0005" class="elsevierStylePara elsevierViewall">We report the case of a 68-year-old male with a medical history of diabetes mellitus type 2, arterial hypertension, severe obstructive sleep apnea and ischemic cerebrovascular disease who was admitted to our hospital for elective cardiac surgery, due to multivessel coronary artery disease after a non-ST-elevation myocardial infarction.</p><p id="par0010" class="elsevierStylePara elsevierViewall">During the first day of hospitalization the patient had two episodes of fever above 38<span class="elsevierStyleHsp" style=""></span>°C with shivering and petechial lesions in lower limbs. He denied headache, seizure, caught, chest or abdominal pain. The patient could not recall any contact with animals recently. Only C reactive protein (85.2<span class="elsevierStyleHsp" style=""></span>mg/L), fibrinogen (544<span class="elsevierStyleHsp" style=""></span>mg/dL) and procalcitonin (0.4<span class="elsevierStyleHsp" style=""></span>ng/mL) were slightly elevated.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Catheter-related phlebitis, in the right hand, was observed. To rule out catheter-related bacteremia, four samples of 10<span class="elsevierStyleHsp" style=""></span>mL of blood obtained from the peripheral venous catheter and venopunction were placed into 2 pair of blood culture bottles (BD Bactec® Plus Aerobic/F and Plus Anaerobic/F) and were processed in the BD Bactec® Fx System (BD Diagnostics). Additionally, the peripheral catheter was removed.</p><p id="par0020" class="elsevierStylePara elsevierViewall">After 30 and 35<span class="elsevierStyleHsp" style=""></span>h of incubation, the two aerobic bottles from the catheter and venopunction flagged positive, respectively. Gram stain revealed Gram-positive bacilli (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) that changed to Gram-positive coccobacilli and cocci after 24 and 72<span class="elsevierStyleHsp" style=""></span>h of incubation in solid media (5–7% CO<span class="elsevierStyleInf">2</span> atmosphere at 37<span class="elsevierStyleHsp" style=""></span>°C in BD BBL™ Chocolate II Agar). In this agar, round, small (<2<span class="elsevierStyleHsp" style=""></span>mm), smooth, semitransparent, mucoid, coalescing, and shiny colonies were observed, which became larger and salmon-pink in color with age but not before 4 days of incubation.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Diagnosis and evolution</span><p id="par0025" class="elsevierStylePara elsevierViewall">Identification using MALDI-TOF (Bruker® Daltonics GmbH) directly from the blood culture (triton-formic acid-ethanol extraction) yielded <span class="elsevierStyleItalic">Rhodococcus hoagii</span> as the first proposed identification with a low score of 1.30, and repetition from colonies after 24<span class="elsevierStyleHsp" style=""></span>h of incubation did not produce any result. Based on Gram stain morphology, bacilli in liquid media, coccobacilli and cocci after 24 and 72<span class="elsevierStyleHsp" style=""></span>h of incubation in solid media, respectively (<a class="elsevierStyleCrossRefs" href="#fig0010">Figs. 2B and 3B</a>), and colonies appearance (<a class="elsevierStyleCrossRefs" href="#fig0010">Figs. 2A and 3A</a>), a presumptive diagnosis of <span class="elsevierStyleItalic">Rhodococcus</span> spp. was provided.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">A third set of blood cultures, obtained 6 days after removal of the catheter, achieved the growth of the same microorganism after 5 days of incubation. In this case, a definitive diagnosis was possible with a higher score (1.82) using MALDI-TOF from colonies. During hospital admission serial transthoracic echocardiographies were negative for endocarditis. Surgery was performed one day before this third set flagged positive.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Further species identification was confirmed by the partial sequencing of the 16S ribosomal RNA gene. The purified amplicons were sequenced and the result obtained was compared using BLAST, demonstrating 99% similarity to <span class="elsevierStyleItalic">R. hoagii</span>. The antimicrobial susceptibility testing was determined by MIC test strips (Liofilchem, Inc., Italy) and the results were interpreted according to PK-PD breakpoints defined by EUCAST (<a href="http://www.eucast.org/">www.eucast.org</a>) as follows: imipenem (MIC 2<span class="elsevierStyleHsp" style=""></span>mg/L, susceptible), levofloxacin (MIC 0.75<span class="elsevierStyleHsp" style=""></span>mg/L, susceptible increased exposure), and linezolid (MIC 3<span class="elsevierStyleHsp" style=""></span>mg/L, resistant). After the identification, antibiotic therapy with ciprofloxacin 500<span class="elsevierStyleHsp" style=""></span>mg every 12<span class="elsevierStyleHsp" style=""></span>h was added for 7 days before surgery and 14 days after surgery.</p><p id="par0040" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Rhodococcus</span> spp. is a pleomorphic Gram-positive coccobacillus, varying the percentage of presentation of the coccoid or bacillary form according to the conditions of growth and the phase in which it is. This zoonosis-producing microorganism causes several diseases like granulomatous pneumonia and lung abscess in foals less than six months old. It sporadically infects other mammals including cats, dogs and pigs, in which produces submandibular adenitis, and is being increasingly reported as a cause of infection in immunocompromised humans. Because diphtheroids are regarded as part of normal respiratory microbiota, the importance of <span class="elsevierStyleItalic">R. hoagii</span> as a pulmonary pathogen may not be fully appreciated and its prevalence may be underestimated.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">In humans, <span class="elsevierStyleItalic">R. hoagii</span> is the main representative species related to pathological processes. It is an intracellular pathogen that infects macrophages and polymorphonuclear cells, especially in patients with alterations of the cellular immunity, immunosuppressive treatment, hematological neoplasm and, in general, any type of immunodeficiency<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> causing respiratory infection, skin infection, abscesses, peritonitis, and bacteremia. Infection is possible, although rare, in immunocompetent persons, with different clinical presentations like respiratory disease and cerebellar abscess. In a systematic review including 531 infections caused by <span class="elsevierStyleItalic">R. hoagii</span>,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> no bacteremia related to peripheral venous catheter infections was described. Despite this, catheter-related bacteremia by <span class="elsevierStyleItalic">R. hoagii,</span> although rare, should be considered.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> In terms of treatment, it is important to emphasize that the condition of intracellular pathogen gives <span class="elsevierStyleItalic">R. hoagii</span> some special characteristics such as the need for prolonged treatments with combined antibiotic regimens, especially in immunocompromised patients.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">It is important to recognize the characteristic appearance of these microorganism colonies and its variable morphology in the Gram stain in order to make an adequate early diagnosis, since it may not be adequately identified by MALDI-TOF because the cell wall of <span class="elsevierStyleItalic">R. hoagii</span> stops the complete uptake of energy when fired upon by the laser.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> A Ziehl-Neelsen stain (preferably staining modification that decolorizes slides with 0.5–1% sulfuric acid solution) and biochemical tests as positive catalase and negative oxidase could be helpful in the presence of a low MALDI-TOF score. Its identity can be confirmed by species-specific and cholesterol oxidase (<span class="elsevierStyleItalic">choE</span>) PCR using genomic DNA as template.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Case description" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Diagnosis and evolution" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Conflict of interest" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 892 "Ancho" => 905 "Tamanyo" => 119617 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Gram stain from blood culture bottles (0<span class="elsevierStyleHsp" style=""></span>h), Gram-positive bacilli.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 646 "Ancho" => 1340 "Tamanyo" => 116384 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A) Bacterial growth (1 day), BD BBL™ Chocolate II Agar. (B) Gram stain from colonies, Gram-positive coccobacilli.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 600 "Ancho" => 1340 "Tamanyo" => 135426 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">(A) Bacterial growth (3 days), BD BBL™ Chocolate II Agar. (B) Gram stain from colonies, Gram-positive cocci.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis and management of pulmonary infection due to <span class="elsevierStyleItalic">Rhodococcus equi</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W.V. Lin" 1 => "R.L. Kruse" 2 => "K. Yang" 3 => "D.M. Musher" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.cmi.2018.04.033" "Revista" => array:6 [ "tituloSerie" => "Clin Microbiol Infect" "fecha" => "2019" "volumen" => "25" "paginaInicial" => "310" "paginaFinal" => "315" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29777923" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0035" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Rhodococcus equi</span> infection in HIV-infected individuals: case reports and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Topino" 1 => "V. Galati" 2 => "E. Grilli" 3 => "N. Petrosillo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/apc.2009.0248" "Revista" => array:6 [ "tituloSerie" => "Aids Patient Care STDS" "fecha" => "2010" "volumen" => "24" "paginaInicial" => "211" "paginaFinal" => "222" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20377432" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0040" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Rhodococcus</span> bacteremia in cancer patients is mostly catheter related and associated with biofilm formation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Al Akhrass" 1 => "I. Al Wohoush" 2 => "A.M. Chaftari" 3 => "R. Reitzel" 4 => "Y. Jiang" 5 => "M. Ghannoum" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1371/journal.pone.0032945" "Revista" => array:5 [ "tituloSerie" => "PLoS One" "fecha" => "2012" "volumen" => "7" "paginaInicial" => "e32945" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22427914" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0045" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of the Vitek MS and Bruker matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of <span class="elsevierStyleItalic">Rhodococcus equi</span> and <span class="elsevierStyleItalic">Dietzia</span> spp" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C.R. Ruiz de Alegría" 1 => "L. Pilares" 2 => "F. Marco" 3 => "J. Vila" 4 => "L. Martínez-Martínez" 5 => "J. Navas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/JCM.00377-17" "Revista" => array:5 [ "tituloSerie" => "J Clin Microbiol" "fecha" => "2017" "volumen" => "7" "paginaInicial" => "2255" "paginaFinal" => "2260" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0050" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rapid identification of <span class="elsevierStyleItalic">Rhodococcus equi</span> by a PCR assay targeting the <span class="elsevierStyleItalic">choE</span> gene" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "N. Ladrón" 1 => "M. Fernández" 2 => "J. Agüero" 3 => "B. González-Zorn" 4 => "J.A. Vázquez-Boland" 5 => "J. Navas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/JCM.41.7.3241-3245.2003" "Revista" => array:5 [ "tituloSerie" => "J Clin Microbiol" "fecha" => "2003" "volumen" => "7" "paginaInicial" => "3241" "paginaFinal" => "3245" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/2529993X/0000004200000002/v4_202403030727/S2529993X23002526/v4_202403030727/en/main.assets" "Apartado" => array:4 [ "identificador" => "63560" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Diagnosis at first sight" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/2529993X/0000004200000002/v4_202403030727/S2529993X23002526/v4_202403030727/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2529993X23002526?idApp=UINPBA00004N" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 5 | 0 | 5 |
2024 October | 10 | 4 | 14 |
2024 September | 21 | 1 | 22 |
2024 August | 16 | 4 | 20 |