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Original Article
Overview of diabetes distress in diabetes patients who do not participate in PROLANIS (Chronic Disease Management Program): A pilot study
Fitrawati Arifuddina,b, Yuliana Syama,
Corresponding author
yulianasyamuh@gmail.com

Corresponding author.
, Rosyidah Arafata, Andi Budiyanto Adiputrac
a Faculty of Nursing, Hasanuddin University, Makassar, Indonesia
b Nursing Department, Syekh Yusuf Nursing Academy, Gowa, Indonesia
c Nursing Department, Faculty of Medicine and Health Sciences, Alauddin State Islamic University, Makassar, Indonesia
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Diabetes Mellitus &#40;DM&#41; is still a major world health problem globally&#46; A total of 422 million adults living with DM&#44; and 1&#46;6 million deaths each year are caused directly by the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">1</span></a> It is predicted that 425 million adults with Diabetes in 2007 will increase to 629 million in 2045&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">2</span></a> Indonesia was ranked 9th out of 10 countries with the most significant number of adults &#40;20&#8211;79&#41; with DM in the world&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">3</span></a> Meanwhile&#44; South Sulawesi is ranked the most significant 17th of the province of Indonesia in the prevalence of DM based on 2013&#8211;2018 data&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">4</span></a> This fact indicates the burden of the incidence of DM&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Increased incidence of DM is in line with the increasing complications of the disease&#46; Complications of DM make up the world&#39;s most significant cause of morbidity and mortality&#44; reaching 5&#46;0 million people each year because of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">5</span></a> Uncontrolled DM can lead to more complications such as kidney and heart disease&#44; loss of vision&#44; and even death&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">6</span></a> Although this disease cannot be made well&#44; its complications can still be prevented by carrying out appropriate disease management programs&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">7&#44;8</span></a> Currently&#44; the Indonesian government&#44; through the Ministry of Health&#44; is promoting a Chronic Disease Management Program for type 2 DM and Hypertension&#44; and it is commonly referred to as PROLANIS&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">9</span></a> This program was found to be very effective in controlling the levels of fasting blood sugar&#44; HbA1c&#44; and total cholesterol in patients with type 2 DM &#40;T2DM&#41; on the optimal implementation&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">10</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Living with DM often creates feelings of fear&#44; worry&#44; sadness&#44; stress&#44; and depression&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a> Demands to control blood glucose levels&#44; strict diets&#44; doctors&#44; and medications&#44; sometimes make people with DM experience confusion&#44; which can cause psychological distress&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">8&#44;12</span></a> Psychological Distress in people with DM is commonly referred to as Distress DM &#40;DD&#41;&#46; DD is different from depression&#44; so the assessment is also done separately&#46;<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">12&#44;13</span></a> DD is defined as a fear of having complications or experiencing hypoglycemia&#44; various stresses&#44; tensions&#44; and concerns experienced by people with DM in their daily lives&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The incidence of DM distress in Canada in tertiary care settings is high&#44; as many as 39&#37; of people with DM&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a> While the picture of DM distress in Indonesia&#44; which has been done in a hospital setting showed quite high results as well&#44; as many as 50&#37; suffer from mild distress&#44; 45&#46;5&#37; moderate distress&#44; and 4&#46;5&#37; have high distress&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> The research related to DD in patients with DM&#44; particularly those who did not follow PROLANIS&#44; has been unknown&#46; Therefore&#44; the purpose of this study was to find out the description of DM distress of patients with DM who did not attend PROLANIS&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Method</span><p id="par0025" class="elsevierStylePara elsevierViewall">This is a pilot study using a descriptive approach&#46; The populations in this study were 42 Type 2 DM clients who live in the working area of Balangnipa Community Health Center Sinjai based on data of January 2019&#46; The sample was determined based on inclusion criteria including Aware &#40;Compos mentis&#41;&#44; Willing to be respondents&#44; have a permanent resident&#39;s status with a resident ID card in the scooping areas of Balangnipa Community Health Center Sinjai&#46; Aged &#60;20 years suffer from Type 2 DM for at least six months&#44; and able to read&#44; write&#44; and communicate well in Indonesian&#46; Diabetes Distress is measured using a Diabetic Distress Scale &#40;DDS&#41;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a> questionnaire in Indonesian&#44; which has been translated&#44; reliability&#44; and validity test&#44;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a> which includes four domains&#44; including emotional Distress&#44; Distress with doctors&#47;health professionals&#44; treatment distress&#44; and interpersonal Distress&#46; The datapresented as the frequency distribution of diabetes distress&#44; taken from the &#40;IBM SPSS statistics 20&#41; version application&#44; The ethical clearance approved by the ethics commission of Poltekkes Kemenkes Makassar with approval No&#46; 1038&#47;KEPK-PTKMKS&#47;VIII2019&#46; Respondent also signed informed consent prior to data collection&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Result</span><p id="par0030" class="elsevierStylePara elsevierViewall">We included 38 participants&#46; The mean age<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>SD was 52&#46;65<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;54&#44; most participants are women &#40;84&#46;2&#37;&#41;&#44; with&#44; the marital status of most participants is married &#40;97&#46;38&#37;&#41;&#44; the highest level of education is undergraduate level &#40;44&#46;75&#37;&#41;&#44; and most occupation is Housewives &#40;47&#46;4&#37;&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Based on the duration of DM experience was &#60;5 years &#40;44&#46;7&#37;&#41;&#44; the most participants&#8217;Body Mass Index &#40;BMI&#41; mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>SD was at 24&#46;03<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;062&#44; most treatment therapy is oral drug consumption &#40;23&#46;65&#37;&#41;&#46; Most physical activity is daily house chores &#40;34&#46;2&#37;&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0040" class="elsevierStylePara elsevierViewall">The statistical result confirmed that 17 participants &#40;44&#46;7&#37;&#41; experienced low and moderate-level Distress&#44; and four participants &#40;10&#46;52&#37;&#41; experienced severe Distress&#46; From the distress domains data&#44; the data of emotional burden distress is as much as 15 participants &#40;39&#46;5&#37;&#41; on a severe level and nine participants &#40;23&#46;7&#37;&#41; on a moderate level&#46; In Distress with doctors or health professionals&#44; three participants &#40;7&#46;9&#37;&#41; on a severe level&#44; and twelve participants &#40;31&#46;6&#37;&#41; on a moderate level&#46; In the treatment distress&#44; eight participants &#40;21&#46;1&#37;&#41; on a severe level&#44; and 19 &#40;50&#37;&#41; on a moderate level&#46; In the interpersonal Distress&#44; two participants &#40;5&#46;3&#37;&#41; at the severe level&#44; and 14 participants &#40;36&#46;8&#37;&#41; at the moderate level of distress&#46; The results show that the diabetic Distress of participants is at moderate and severe levels is 55&#46;3&#37;&#44; with the most significant difficulty in emotional burden&#44; followed by treatment distress&#44; interpersonal Distress&#44; and Distress with doctors&#47;health personnel &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Discussion</span><p id="par0045" class="elsevierStylePara elsevierViewall">DD is defined as a fear of complications&#44; fear of experiencing hypoglycemia&#44; and various stresses&#44; tensions&#44; and concerns experienced by people with DM in their daily lives&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a> In the process of controlling DM&#44; the patient plays a vital role in maintaining his daily chronic condition&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">8</span></a> They must follow the right program in managing their illness independently&#44; such as a healthy diet&#44; adequate physical activity&#44; and adherence to medication&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">8&#44;12</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The previous study shows some significant factors related to lower DDS were older age&#44; lower BMI&#44; higher self-efficacy&#44; higher levels of health care provider support&#44; and a healthy diet&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">18</span></a> HbA1c&#44; treatment modalities&#44; duration of DM&#44; diabetic complications&#44; and average monthly family income appeared to be significant predicting factors of diabetes distress among type 2 diabetes mellitus patients&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">19</span></a> Another study also shows that the duration of DM is in line with the lower DD status&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The lower DD status in the respondent in this research were analyzed from some factors that are age&#44; sex&#44; marital status&#44; education&#44; occupation&#44; duration of diabetes&#44; BMI&#44; therapy&#44; and physical activity&#46; In this research&#44; most respondents are women&#44; with the mean age was 52&#46;65 years old&#44; the marital status of most respondents is married&#44; the highest level of education is the first stratum&#44; and most occupations are Housewives&#46; Based on the duration of DM experience was &#60;5 years&#44; the respondent&#39;s BMI mean was at 24&#46;03&#44; most treatment therapy is oral drug consumption&#44; and most physical activity is daily house chores&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">The results showed that moderate and high levels of Diabetes Distress were experienced by more than half of DM sufferers who did not attend PROLANIS&#46; This is not so different&#44; but it is higher compared to the results of previous studies on DM patients generally treated in hospitals by Nurmaguphita and Sugiyanto &#40;2018&#41;&#44; which showed quite high results as well&#44; as many as 50&#37;&#44; suffer from moderate and high distress&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> These results indicate that the Diabetes Distress of DM sufferers who do not follow PROLANIS is slightly higher compared to DM sufferers in general&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Besides&#44; the most significant level of Distress in this research is emotional Distress&#44; followed by treatment distress&#46; This is in line with previous research&#44; which also is on emotional burden distress followed by treatment distress&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> Another research also explained that the most dominant component to the emergence of patient Distress is the emotional burden and response to health workers&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a> Also&#44; diabetes distress&#44; especially stress related to self and emotional care&#44; plays an essential role in glycemic control&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">In managing diabetes distress&#44; several things need to be done&#46; First&#44; know&#46; When someone thinks they have DD&#44; it is suggested not to be surprised&#44; because it happens to many people living with Diabetes&#46; Second&#44; talking to Diabetes educators&#44; they can ask relevant questions&#46; Third&#44; do a DD assessment with a simple test like the diabetes distress questionnaire&#46; Furthermore&#44; the results of this test will help identify the most troublesome areas of Diabetes&#46; Then&#44; based on these results&#44; further treatment plans can be developed&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> As for the coping mechanism of Diabetes&#44; Gebel &#40;2013&#41; wrote a coping strategy carried out by three members of the diabetes reading panel reader who interpreted this and how they coped with it&#46; The first coping strategy is to accept that not everything can be controlled&#44; seek support from people who have experienced the same thing&#44; and get closer to faith or faith and family&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">22</span></a> Family empowerment was written to be an effective strategy in metabolic controls in people with diabetes&#46; Independent support from family members or close friends has the effect of support primary health and can contribute to better glycemic control by improving the harmful effects of diabetes distress&#46;<a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">22&#8211;25</span></a></p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conclusion</span><p id="par0075" class="elsevierStylePara elsevierViewall">Based on the results it can be concluded that moderate to severe levels of Diabetes Distress is experienced by more than half of DM sufferers who did not follow PROLANIS&#44; with the highest level of Distress in emotional burden distress followed by treatment distress&#44; interpersonal Distress&#44; and doctor&#47;health care distress&#46; From these results&#44; it can be suggested the need for a diabetes education approach that is more effective and efficient for patients who do not or have not participated in the PROLANIS program due to distance and time limitations&#44; for example by utilizing telenursing or tele-coaching methods related to increasing the emotional response of DM sufferers which can be in the form of education&#44; counseling&#44; or communication therapy to improve coping&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflict of interest</span><p id="par0080" class="elsevierStylePara elsevierViewall">The authors declare no conflict of interest&#46;</p></span></span>"
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          "identificador" => "sec0030"
          "titulo" => "Conflict of interest"
        ]
        8 => array:2 [
          "identificador" => "xack577500"
          "titulo" => "Acknowledgments"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2021-01-04"
    "fechaAceptado" => "2021-07-19"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1459208"
          "palabras" => array:3 [
            0 => "Diabetes mellitus"
            1 => "Diabetes distress"
            2 => "PROLANIS"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To describe the diabetes distress of Diabetes Mellitus &#40;DM&#41; patients who do not follow PROLANIS in Sinjai&#44; eastern Indonesia&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This is a pilot study using a descriptive approach&#46; A total of 38 types 2 Non-Prolanis DM patients were recruited by purposive sampling in August 2019&#46; Instruments used were sociodemographic and DDS17 questionnaires&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Statistical results show that most respondents experienced low and moderate-level Distress &#40;44&#46;7&#37; each&#41; and some others &#40;10&#46;5&#37;&#41; high-level Distress&#46; The mean score of Diabetes distress based on high to low domains are emotional burden distress &#40;2&#46;00&#41;&#44; treatment distress &#40;1&#46;92&#41;&#44; interpersonal Distress &#40;1&#46;68&#41;&#44; and Distress with doctors&#47;health professionals &#40;1&#46;42&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">It was found that the diabetes distress of Non-PROLANIS DM patients in the working area of Puskesmas Balangnipa Sinjai at moderate and high levels&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objective"
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          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Method"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusion"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0030">Peer-review process of the 3rd International Nursing &#38; Health Sciences Students &#38; Health Care Professionals Conference &#40;INHSP&#41; 2019 is under the responsibility of the scientific committee of the 3rd International Nursing &#38; Health Sciences Students &#38; Health Care Professionals Conference &#40;INHSP&#41;&#46; Full-text and the content of it is under the responsibility of authors of the article&#46;</p>"
      ]
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        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
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        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
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            0 => array:2 [
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                  \t\t\t\t" scope="col">Participant characteristic&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Man&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">52&#46;65<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;54&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">97&#46;38&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">2&#46;62&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Elementary&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">12&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">31&#46;6&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Junior High&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">15&#46;8&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Senior High&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">13&#46;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diploma&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">44&#46;75&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">2&#46;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">34&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Housewives&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Frequency distribution of participants characteristic&#46;</p>"
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                0 => """
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                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Participants characteristic&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">N</span> &#40;38&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;5 years&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">44&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805;5 years&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">15&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">39&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62;10 years&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">BMI</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>SD&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#46;03<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;062&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="3" align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Oral&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">23&#46;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Insulin&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Herbal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Oral insulin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Oral herbal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">7&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">18&#46;45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Oral insulin herbal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">5&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Without therapy&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">21&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Physical exercise 3&#8211;5&#215;&#47;week&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">15&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Gymnastics 1&#8211;2&#215;&#47;week&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Daily housework&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">34&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No&#47;Rarely sports&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">7&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;4&nbsp;\t\t\t\t\t\t\n
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                  """
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        "descripcion" => array:1 [
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        ]
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t" scope="col">DD degree&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="center" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">DD<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a></th><th class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="center" valign="\n
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                  \t\t\t\t  " colspan="2" align="center" valign="\n
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos