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In addition to increased LOS tone (48 mmHg), we found increased integrated relaxation pressure (25 and 23 mmHg/4 s lying down and upright respectively) and pan-oesophageal pressurisation without peristaltic wave generation, manometry findings compatible with type II oesophageal achalasia. PIP: pressure inversion point; TZ: transition zone.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Elena Pérez Campos, Ana Delgado Maroto, José López González" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Elena" "apellidos" => "Pérez Campos" ] 1 => array:2 [ "nombre" => "Ana" "apellidos" => "Delgado Maroto" ] 2 => array:2 [ "nombre" => "José" "apellidos" => "López González" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210570523003497" "doi" => "10.1016/j.gastrohep.2023.06.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570523003497?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382424000622?idApp=UINPBA00004N" "url" => "/24443824/0000004700000003/v2_202405192000/S2444382424000622/v2_202405192000/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image of the month</span>" "titulo" => "Hepatomegaly from pancreatic cancer metastasis" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "268" "paginaFinal" => "269" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Umberto G. Rossi, Andrea DeCensi" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Umberto G." "apellidos" => "Rossi" "email" => array:2 [ 0 => "urossi76@hotmail.com" 1 => "umberto.rossi@galliera.it" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Andrea" "apellidos" => "DeCensi" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Department of Radiological Area, Interventional Radiology Unit, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128 Genova, Italy" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Department of Medical Area, Oncology Unit, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128 Genova, Italy" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hepatomegalia por metástasis de cáncer de páncreas" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 475 "Ancho" => 905 "Tamanyo" => 102748 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A and B) Contrast-enhanced multi-detector computed tomography coronal MPR (A) and VRT (B) reconstruction that confirm multiple hepatic nodules (arrows) and a huge hepatomegaly up to pelvis.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 65-year-old female, was sent to our hospital for weight loss of 8<span class="elsevierStyleHsp" style=""></span>kg in four months, right abdominal pain and asthenia. Clinical evaluation highlighted a hepatomegaly up to pelvis with hard consistency on palpation. Serum laboratory studies showed the following abnormal values: pancreatic amylase 84<span class="elsevierStyleHsp" style=""></span>U/L, aspartate aminotransferase 69<span class="elsevierStyleHsp" style=""></span>U/L, alanine aminotransferase 61<span class="elsevierStyleHsp" style=""></span>U/L, gamma-glutamyl transferase 214<span class="elsevierStyleHsp" style=""></span>UI/L, alkaline phosphatase 191<span class="elsevierStyleHsp" style=""></span>U/L and carbohydrate antigen 19–9104<span class="elsevierStyleHsp" style=""></span>U/ml<span class="elsevierStyleItalic">.</span> Abdomen Multi-detector computed tomography imaging axial (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), coronal MIP and VRT reconstruction (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A and B) demonstrated multiple hepatic nodules (arrows) occupying almost all liver parenchyma and a single nodule at the pancreatic tail (arrowhead). US-guided liver biopsy demonstrated the diagnosis of metastatic pancreatic adenocarcinoma. Patient has just started chemotherapy with nabplaclitaxel and gemcitabine, with the aim of reduction of tumour masses and pain relief.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Liver metastases from pancreatic cancer are present in 37–41.9% of cases already in the first clinical diagnosis.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> Therefore, an accurate evaluation of possible locoregional and/or distant metastases in patients with pancreatic cancer is crucial, in order to indicate clinical treatment.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">1–3</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Authors’ contributions</span><p id="par0015" class="elsevierStylePara elsevierViewall">Umberto G. Rossi: write paper, diagnosis, images.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Andrea DeCensi: review paper, treatment.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Funding</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that there is no funding.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that there is no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Authors’ contributions" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Funding" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Conflict of interest" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 627 "Ancho" => 755 "Tamanyo" => 63227 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Contrast-enhanced multi-detector computed tomography axial images that shows multiple hepatic nodules (arrows) and a single nodule at the pancreatic tail (arrowhead).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 475 "Ancho" => 905 "Tamanyo" => 102748 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A and B) Contrast-enhanced multi-detector computed tomography coronal MPR (A) and VRT (B) reconstruction that confirm multiple hepatic nodules (arrows) and a huge hepatomegaly up to pelvis.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer statistics, 2021" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.L. Siegel" 1 => "K.D. Miller" 2 => "H.E. Fuchs" 3 => "A. Jemal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3322/caac.21654" "Revista" => array:6 [ "tituloSerie" => "CA Cancer J Clin" "fecha" => "2021" "volumen" => "71" "paginaInicial" => "7" "paginaFinal" => "33" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33433946" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unclassifiable pancreatic tumour. a case report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.P. Nieto" 1 => "J.Y. Zhou" 2 => "M.R. Blanco" 3 => "J. Szafranska" 4 => "S.S. Cabús" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.gastrohep.2021.02.008" "Revista" => array:6 [ "tituloSerie" => "Gastroenterol Hepatol" "fecha" => "2021" "volumen" => "44" "paginaInicial" => "559" "paginaFinal" => "561" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33746027" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular markers of pancreatic cancer: a 10-year retrospective review of molecular advances" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B.E. Jacks" 1 => "C.U. Ekpemiro" 2 => "A.A. Adeosun" 3 => "U.O. Ogbonna" 4 => "F.T. Ogundiran" 5 => "F. Babalola" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.7759/cureus.29485" "Revista" => array:5 [ "tituloSerie" => "Cureus" "fecha" => "2022" "volumen" => "14" "paginaInicial" => "e29485" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/36299966" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/24443824/0000004700000003/v2_202405192000/S2444382424001330/v2_202405192000/en/main.assets" "Apartado" => array:4 [ "identificador" => "75461" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images of the month" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/24443824/0000004700000003/v2_202405192000/S2444382424001330/v2_202405192000/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382424001330?idApp=UINPBA00004N" ]
Journal Information
Vol. 47. Issue 3.
Pages 268-269 (March 2024)
Vol. 47. Issue 3.
Pages 268-269 (March 2024)
Image of the month
Hepatomegaly from pancreatic cancer metastasis
Hepatomegalia por metástasis de cáncer de páncreas
Article information
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