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"descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan: asymmetric mural thickening of the ascending colon (arrow) with fat reticulation and adjacent vascular engorgement.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">This was a 64-year-old man undergoing chemotherapy for TNM stage T4N2M0 squamous cell carcinoma of the lung.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A follow-up CT scan 10 months after diagnosis showed mural thickening of the ascending colon (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). A colonoscopy was performed and a superficial ulcer of non-specific appearance was observed in the right colon (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Histopathology was consistent with colonic metastasis of lung squamous cell carcinoma (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Currently, 6 months after the endoscopy, the patient still has no gastrointestinal symptoms and is being treated with the previous chemotherapy regimen.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Gastrointestinal (GI) metastases from primary lung cancer are rare, varying in incidence between 0.3% and 1.7%. The most common GI sites are the oesophagus (6.3%), small intestine (2.6%), stomach (1.2%) and colon (0.7%).<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The histological subtype of primary lung neoplasm most commonly associated with GI metastases is much debated,<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> with a recent series finding large cell carcinoma to be the most prevalent.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Most of these patients are asymptomatic.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> Treatment is usually chemotherapy, although in complicated cases (perforation, obstruction, haemorrhage, etc.) surgery may be considered. No therapy has been shown to have an impact on survival.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1264 "Ancho" => 1005 "Tamanyo" => 136156 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan: asymmetric mural thickening of the ascending colon (arrow) with fat reticulation and adjacent vascular engorgement.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 877 "Ancho" => 1005 "Tamanyo" => 139020 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Endoscopic findings: ulcerated lesion in ascending colon.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1440 "Ancho" => 2007 "Tamanyo" => 605930 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Pathology: (A) haematoxylin-eosin ×2: colon biopsy with marked inflammation (arrow); and (B) haematoxylin-eosin ×10: colon biopsy with neoplastic cellular nidus. (C) Neoplastic cellularity positive for anti-P40 antibody in colon (×20); and (D) endobronchial primary lesion (×20) confirming squamous origin.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gastrointestinal metastasis from primary lung cancer. Case series and systematic literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Balla" 1 => "J.D. Subiela" 2 => "J. Bollo" 3 => "C. Martinez" 4 => "C. Rodriguez Luppi" 5 => "P. 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Han" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00432-008-0424-0" "Revista" => array:6 [ "tituloSerie" => "J Cancer Res Clin Oncol" "fecha" => "2009" "volumen" => "135" "paginaInicial" => "297" "paginaFinal" => "301" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18512073" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/24443824/0000004700000002/v1_202404260624/S2444382424000294/v1_202404260624/en/main.assets" "Apartado" => array:4 [ "identificador" => "75461" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images of the month" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/24443824/0000004700000002/v1_202404260624/S2444382424000294/v1_202404260624/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382424000294?idApp=UINPBA00004N" ]
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Vol. 47. Issue 2.
Pages 186-187 (February 2024)
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Vol. 47. Issue 2.
Pages 186-187 (February 2024)
Image of the month
Metastasis from primary lung cancer of unusual location
Metástasis de origen pulmonar de localización inusual
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From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail