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Inicio Gastroenterología y Hepatología (English Edition) The influence of the SARS-CoV-2 pandemic on in-hospital mortality in a gastroent...
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Vol. 46. Issue 7.
Pages 522-530 (August - September 2023)
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Vol. 46. Issue 7.
Pages 522-530 (August - September 2023)
Original article
The influence of the SARS-CoV-2 pandemic on in-hospital mortality in a gastroenterology service
Influencia de la pandemia por SARS-CoV-2 en la mortalidad intrahospitalaria en un servicio de aparato digestivo
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Alberto M. García-Garcíaa,, Jose M. Pinazo-Banderaa,b,,
Corresponding author
josepinazo@hotmail.es

Corresponding author.
, Galilea Asady Bena, Miren García-Cortésa,b,c, Raúl J. Andradea,b,c
a Virgen de la Victoria University Hospital, Gastroenterology Service, Málaga, Spain
b Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma Bionand, Málaga, Spain
c Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain
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Figures (1)
Tables (5)
Table 1. Admissions for non-variceal gastrointestinal bleeding in the Gastroenterology Service.
Table 2. Admissions for biliopancreatic events in the Gastroenterology Service.
Table 3. Admissions for primary liver disease or complications of cirrhosis in the Gastroenterology Service.
Table 4. Admissions for Inflammatory Bowel Disease in the Gastroenterology Service.
Table 5. Tumours diagnosed during hospitalisation in the Gastroenterology Service.
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Abstract
Introduction

The pandemic caused by SARS-CoV-2 has drastically changed the global health landscape. Our objective was to verify if, after the start of the pandemic, there was an increase in in-hospital mortality in patients admitted to a Gastroenterology Service of a 3rd level hospital.

Material and methods

The 1039 admissions registered at the Virgen de la Victoria University Hospital in Malaga (Spain) were retrospectively analysed in the period between 1 December 2019 and 30 November 2020 (12 months), which were divided into 4 quarters (pre-wave, first wave, inter-wave and second wave) and mortality and other variables (globally and by disease group) were analysed.

Results

No statistically significant differences were observed in terms of overall in-hospital mortality in the different periods. (p 0.23). The greatest burden of disease corresponded to biliopancreatic group and, within them, acute pancreatitis (p 0.04), followed by non-variceal gastrointestinal bleeding. In the second semester, mortality increased in the biliopancreatic group (p 0.01). Patients admitted for gastrointestinal bleeding took longer to request care after the start of the pandemic, especially in the second wave (p 0.03). The same was observed in admissions due to tumours, with the time elapsed until the emergency visit more than double in the second semester, with a consequent increase in mortality (p 0.00).

Conclusions

The global in-hospital mortality in a Gastroenterology Service in a 3rd level hospital has not increased with the onset of the SARS-CoV-2 pandemic, however, a higher in-hospital mortality has been recorded in biliopancreatic diseases and digestive tumours diagnosed on an in-patient basis between June and November 2020.

Keywords:
COVID-19
SARS-Cov-2
Mortality
Hospitalisation
Gastroenterology service
Abbreviations:
COVID-19
SARS-CoV-2
WHO
ICU
IBD
SD
Resumen
Introducción

La pandemia ocasionada por el SARS-CoV-2 ha modificado drásticamente el panorama sanitario mundial. Nuestro objetivo fue comprobar si tras el inicio de esta se produjo un aumento en la mortalidad intrahospitalaria en los pacientes ingresados en un servicio de aparato digestivo de un hospital de tercer nivel.

Material y métodos

Se analizaron retrospectivamente 1.039 ingresos en el Servicio de Aparato Digestivo del Hospital Universitario Virgen de la Victoria en el periodo comprendido entre el 1 de diciembre de 2019 y el 30 de noviembre de 2020 (12 meses), se dividieron en 4 trimestres (preoleada, primera oleada, interoleada y segunda oleada) y se analizó la mortalidad y otras variables (de forma global y por grupo de enfermedades).

Resultados

No se observaron diferencias estadísticamente significativas en cuanto a mortalidad intrahospitalaria global en los diferentes periodos (p=0,23). La enfermedad con mayor predominio fue la biliopancreática y, dentro de ella, las pancreatitis agudas (p=0,04), seguidas del sangrado digestivo no varicoso. En el segundo semestre aumentó la mortalidad en el grupo biliopancreático (p=0,01). Los pacientes que ingresaron por hemorragia digestiva tardaron más en solicitar asistencia tras la pandemia, especialmente en la segunda oleada (p=0,03). Esto mismo se objetivó en los ingresos por tumores, siendo el tiempo transcurrido hasta la consulta a Urgencias mayor del doble en el segundo semestre, con el consecuente aumento en la mortalidad (p=0,00).

Conclusiones

La mortalidad global intrahospitalaria en el Servicio de Aparato Digestivo no ha aumentado con la sobrevenida de la pandemia por SARS-CoV-2, si bien se ha registrado una mayor mortalidad intrahospitalaria en las enfermedades biliopancreáticas y los tumores digestivos diagnosticados en régimen de hospitalización entre junio y noviembre de 2020.

Palabras clave:
COVID-19
SARS-CoV-2
Mortalidad
Hospitalización
Servicio de aparato digestivo

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