was read the article
array:23 [ "pii" => "S2444382423000901" "issn" => "24443824" "doi" => "10.1016/j.gastre.2022.06.006" "estado" => "S300" "fechaPublicacion" => "2023-06-01" "aid" => "1964" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2022" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Gastroenterol Hepatol. 2023;46:489-90" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0210570522001716" "issn" => "02105705" "doi" => "10.1016/j.gastrohep.2022.06.006" "estado" => "S300" "fechaPublicacion" => "2023-06-01" "aid" => "1964" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Gastroenterol Hepatol. 2023;46:489-90" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>" "titulo" => "Infiltración eosinofílica hepática: ¿cáncer o parásito?" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "489" "paginaFinal" => "490" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Hepatic eosinophilic infiltration: Cancer or parasite?" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 424 "Ancho" => 1005 "Tamanyo" => 79596 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Tomografía computarizada de abdomen obtenida tras la administración intravenosa de contraste en fase arterial (A) y portal (B). Lesión sólida hipodensa en el segmento hepático V, de nueva aparición (flechas blancas), con alteración perfusional perilesional en la fase arterial (asteriscos).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Miguel Sogbe, Andrés Blanco-Di Matteo, Isberling Madeleine Di Frisco, Ana Ezponda, José Luis del Pozo" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Miguel" "apellidos" => "Sogbe" ] 1 => array:2 [ "nombre" => "Andrés" "apellidos" => "Blanco-Di Matteo" ] 2 => array:2 [ "nombre" => "Isberling Madeleine" "apellidos" => "Di Frisco" ] 3 => array:2 [ "nombre" => "Ana" "apellidos" => "Ezponda" ] 4 => array:2 [ "nombre" => "José Luis" "apellidos" => "del Pozo" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2444382423000901" "doi" => "10.1016/j.gastre.2022.06.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382423000901?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570522001716?idApp=UINPBA00004N" "url" => "/02105705/0000004600000006/v2_202306121247/S0210570522001716/v2_202306121247/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S2444382423000913" "issn" => "24443824" "doi" => "10.1016/j.gastre.2022.09.006" "estado" => "S300" "fechaPublicacion" => "2023-06-01" "aid" => "1992" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "rev" "cita" => "Gastroenterol Hepatol. 2023;46:483-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review</span>" "titulo" => "Endoscopic diagnosis of <span class="elsevierStyleItalic">H. pylori</span> infection" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "483" "paginaFinal" => "488" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Diagnóstico endoscópico de la infección por <span class="elsevierStyleItalic">H. pylori</span>" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 814 "Ancho" => 905 "Tamanyo" => 141457 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Normal pattern of the mucosa of the gastric body with endoscopy without magnification (Fujifilm "blue laser imaging" [BLI]) observing the glands which are arranged vertically and the openings of the rounded crypts.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rodrigo Garcés-Durán, Joan Llach, Angella Da Fierno, Henry Córdova, Gloria Fernández-Esparrach" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Rodrigo" "apellidos" => "Garcés-Durán" ] 1 => array:2 [ "nombre" => "Joan" "apellidos" => "Llach" ] 2 => array:2 [ "nombre" => "Angella" "apellidos" => "Da Fierno" ] 3 => array:2 [ "nombre" => "Henry" "apellidos" => "Córdova" ] 4 => array:2 [ "nombre" => "Gloria" "apellidos" => "Fernández-Esparrach" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210570522002266" "doi" => "10.1016/j.gastrohep.2022.09.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570522002266?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382423000913?idApp=UINPBA00004N" "url" => "/24443824/0000004600000006/v2_202311101547/S2444382423000913/v2_202311101547/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Hepatic eosinophilic infiltration: Cancer or parasite?" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor,</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "489" "paginaFinal" => "490" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Miguel Sogbe, Andrés Blanco-Di Matteo, Isberling Madeleine Di Frisco, Ana Ezponda, José Luis del Pozo" "autores" => array:5 [ 0 => array:3 [ "nombre" => "Miguel" "apellidos" => "Sogbe" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 1 => array:4 [ "nombre" => "Andrés" "apellidos" => "Blanco-Di Matteo" "email" => array:1 [ 0 => "ablancod@unav.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Isberling Madeleine" "apellidos" => "Di Frisco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "Ana" "apellidos" => "Ezponda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 4 => array:3 [ "nombre" => "José Luis" "apellidos" => "del Pozo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Servicio de Enfermedades Infecciosas y Microbiología, Clínica Universidad de Navarra, Pamplona, Navarra, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Medicina Interna, Clínica Universidad de Navarra, Pamplona, Navarra, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Departamento de Neumología, Clínica Universidad de Navarra, Pamplona, Navarra, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Departamento de Radiología, Clínica Universidad de Navarra, Pamplona, Navarra, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Infiltración eosinofílica hepática: ¿cáncer o parásito?" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 433 "Ancho" => 1005 "Tamanyo" => 71418 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Computed tomography of the abdomen obtained after intravenous administration of contrast in arterial (A) and portal (B) phases. Virtual resolution of the liver lesion identified in the previous scan. Only a very small hypodense lesion persists in the portal phase, which in the current study seems cystic in nature (white arrow), with a residual appearance.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Hypereosinophilia is a rare finding defined as an absolute eosinophil count >1500/µl. Eosinophilia can cause infiltration in different organs, with liver and gastrointestinal tract involvement being the most common.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The purpose of this letter to the editor is to describe hepatic eosinophilic infiltration (HEI) in the context of hypereosinophilic syndrome secondary to <span class="elsevierStyleItalic">Strongyloides stercoralis</span> infection.</p><p id="par0010" class="elsevierStylePara elsevierViewall">This was a 62-year-old male, residing in Africa, with a history of left partial nephrectomy for clear cell carcinoma, who attended a urological check-up asymptomatic. Computed tomography (CT) of the abdomen was performed, showing a hypointense lesion measuring 29 mm in diameter in segment V of the liver, and abnormal perfusion (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Laboratory tests showed hypereosinophilia of 1840/µl with no other findings. Suspecting metastasis, a liver biopsy was performed, revealing sinusoidal infiltration of eosinophils (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>), for which Infectious Diseases were asked to assess. A microbiological study was carried out with serology for: schistosomiasis, amoebiasis, anisakiasis, cysticercosis, strongyloidiasis, fascioliasis, hydatidosis and visceral larva <span class="elsevierStyleItalic">migrans</span>. A thick blood smear was also obtained, with no evidence of pathogens, as with the examination of faeces for parasites. The serology results were negative, except for IgG strongyloidiasis, which was positive (index: 4.337).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">After ruling out <span class="elsevierStyleItalic">Loa loa</span> coinfection by serology, the patient was started on ivermectin 200 µg/kg for two days. At follow-up four months later, CT of the abdomen to monitor for liver damage showed resolution of the focal lesion in segment V (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>) and analysis showed return to normal of the patient's eosinophil count (290/µl).</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">HEI can manifest with radiological findings suggestive of neoplasia, so malignancy has to be ruled out.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> CT images of HEI are usually of small, poorly defined, hypointense lesions, more noticeable in the portal phase. The presence of a liver lesion associated with hypereosinophilia is suggestive of HEI. The combination of clinical and laboratory data may be enough to distinguish an HEI from a malignant lesion. In addition, in our case, the epidemiological risk, normal liver function tests, and the absence of elevated inflammatory parameters made the diagnosis of HEI more likely. Biopsy could have been saved for the event of not responding to anthelmintic treatment or the case of malignancy being strongly suspected.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The most common causes of hypereosinophilia include parasitic infections, hypersensitivity reactions, connective tissue diseases, vasculitis, cancers and paraneoplastic syndromes. Some of the most common parasitic infections are caused by: <span class="elsevierStyleItalic">Toxocara canis</span>, <span class="elsevierStyleItalic">Fasciola hepatica</span>, <span class="elsevierStyleItalic">Clonorchis sinensis</span>, <span class="elsevierStyleItalic">Paragonimus westermani</span>, <span class="elsevierStyleItalic">Taenia solium</span> and <span class="elsevierStyleItalic">S. stercoralis</span>.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Strongyloidiasis is an infection caused by the helminth <span class="elsevierStyleItalic">S. stercoralis</span>, which is able to complete its life cycle inside the human host. Approximately 75% of all infections worldwide occur in Southeast Asia, Africa and the Western Pacific regions.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a> The most common mode of transmission is through skin contact with contaminated soil. Strongyloidiasis can be asymptomatic or associated with non-specific complaints in more than half of cases, particularly in the chronic forms. In patients with subclinical infection who subsequently become immunosuppressed (corticosteroids, organ transplantation), larval reproduction can lead to disseminated infection. Chronic infection can become apparent in the form of eosinophilia and liver lesions.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a> Liver lesions caused by <span class="elsevierStyleItalic">S. stercoralis</span> are the result of parasite migration in the liver parenchyma in the context of a disseminated disease caused by hyperinfection. However, they do not normally cause hypereosinophilia and the parasite is usually visible in the liver biopsy.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Serology testing is the preferred diagnostic method, as it is more sensitive than stool analysis. Most serology tests measure the IgG response to an extract of larvae obtained from experimentally infected animals or related species of <span class="elsevierStyleItalic">Strongyloides</span> spp.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a> The treatment of choice is ivermectin. In patients from areas endemic for Loiasis, a screening for loasis microfilaraemia (blood smear) should be performed prior to administration, as treatment with ivermectin in cases of a high parasite load may precipitate a potentially fatal Mazzotti reaction (fever, hypotension, encephalitis, etc).<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they received no funding to conduct this study.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">José Luis del Pozo has participated in training or consulting activities funded by Pfizer, MSD, Gilead and Novartis.</p><p id="par0045" class="elsevierStylePara elsevierViewall">The other authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 424 "Ancho" => 1005 "Tamanyo" => 79622 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Computed tomography of the abdomen obtained after intravenous administration of contrast in arterial (A) and portal (B) phases. Solid hypodense lesion in segment V of the liver, newly appeared (white arrows), with perilesional perfusion abnormality in the arterial phase (asterisks).</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 419 "Ancho" => 905 "Tamanyo" => 127548 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Massive sinusoidal infiltration of eosinophils, compatible with eosinophilic hepatitis.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 433 "Ancho" => 1005 "Tamanyo" => 71418 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Computed tomography of the abdomen obtained after intravenous administration of contrast in arterial (A) and portal (B) phases. Virtual resolution of the liver lesion identified in the previous scan. Only a very small hypodense lesion persists in the portal phase, which in the current study seems cystic in nature (white arrow), with a residual appearance.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Approach to Patients with Eosinophilia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F.L. Kuang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.mcna.2019.08.005" "Revista" => array:6 [ "tituloSerie" => "Med Clin North Am" "fecha" => "2020" "volumen" => "104" "paginaInicial" => "1" "paginaFinal" => "14" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31757229" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "What are the clinical features and etiology of eosinophilic liver infiltration?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.W. Sim" 1 => "D.J. Son" 2 => "E. Cho" 3 => "S.K. Choi" 4 => "S.S. Shin" 5 => "C.H. Jun" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5009/gnl18266" "Revista" => array:6 [ "tituloSerie" => "Gut Liver" "fecha" => "2019" "volumen" => "13" "paginaInicial" => "183" "paginaFinal" => "190" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30376702" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Focal eosinophilic infiltration of the liver, benign or malignant?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W. Claeys" 1 => "A. Delie" 2 => "P. Smeets" 3 => "M. De Scheerder" 4 => "H. Degroote" 5 => "X. Verhelst" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/ccr3.4448" "Revista" => array:6 [ "tituloSerie" => "Clin Case Reports" "fecha" => "2021" "volumen" => "9" "paginaInicial" => "1" "paginaFinal" => "5" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26793012" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical Features Associated with Strongyloidiasis in Migrants and the Potential Impact of Immunosuppression: A Case Control Study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Martinez-Pérez" 1 => "M.J. Soriano-Pérez" 2 => "F. Salvador" 3 => "J. Gomez-Junyent" 4 => "J. Villar-Garcia" 5 => "M. Santin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3390/pathogens9060507" "Revista" => array:5 [ "tituloSerie" => "Pathogens" "fecha" => "2020" "volumen" => "9" "paginaInicial" => "507" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32585975" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Strongyloidiasis: A Neglected Tropical Disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Krolewiecki" 1 => "T.B. Nutman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.idc.2018.10.006" "Revista" => array:6 [ "tituloSerie" => "Infect Dis Clin North Am" "fecha" => "2019" "volumen" => "33" "paginaInicial" => "135" "paginaFinal" => "151" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30712758" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/24443824/0000004600000006/v2_202311101547/S2444382423000901/v2_202311101547/en/main.assets" "Apartado" => array:4 [ "identificador" => "48445" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/24443824/0000004600000006/v2_202311101547/S2444382423000901/v2_202311101547/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382423000901?idApp=UINPBA00004N" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 8 | 0 | 8 |
2024 October | 81 | 1 | 82 |
2024 September | 78 | 0 | 78 |
2024 August | 71 | 2 | 73 |
2024 July | 64 | 0 | 64 |
2024 June | 45 | 0 | 45 |
2024 May | 67 | 0 | 67 |
2024 April | 71 | 2 | 73 |
2024 March | 69 | 2 | 71 |
2024 February | 78 | 0 | 78 |
2024 January | 103 | 0 | 103 |
2023 December | 95 | 3 | 98 |
2023 November | 99 | 0 | 99 |
2023 October | 86 | 0 | 86 |
2023 September | 49 | 0 | 49 |
2023 August | 30 | 0 | 30 |
2023 July | 25 | 0 | 25 |
2023 June | 6 | 0 | 6 |
2023 May | 0 | 1 | 1 |