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Inicio Hipertensión y Riesgo Vascular Incidentaloma adrenal e hipertensión arterial
Journal Information
Vol. 25. Issue 2.
Pages 77-80 (March 2008)
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Vol. 25. Issue 2.
Pages 77-80 (March 2008)
Incidentaloma adrenal e hipertensión arterial
Adrenal incidentaloma and high blood pressure
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3396
G. Alonso García
Corresponding author
galonso2@yahoo.com.ar

Correspondencia: Servicio de Endocrinología.Hospital Universitario San Cecilio.Avda. Doctor Olóriz, 16.18012 Granada. España.
, D. Fernández García, R. Reyes García
Servicio de Endocrinología. Hospital Universitario San Cecilio. Granada. España
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El incidentaloma adrenal se define como el hallazgo casual de una lesión adrenal evidenciada durante un estudio de imagen abdominal y su incidencia en la población general es del 4-6%. Entre las etiologías posibles se incluyen lesiones benignas o malignas que pueden ser hormonalmente activas o inactivas. Datos recientes sugieren que la incidencia de hiperaldosteronismo primario (HAP) en pacientes hipertensos puede alcanzar hasta un 10%, representando una de las causas más frecuentes de hipertensión arterial secundaria. En la mayoría de los casos el HAP es causado por un adenoma adrenal productor de aldosterona (APA) o hiperplasia bilateral idiopática. Evidencias recientes sugieren que la aldosterona ejerce un efecto deletéreo directo sobre el sistema cardiovascular incrementando la incidencia de eventos cardiovasculares y cerebrovasculares. Se expone el caso clínico de una mujer de 38 años con hipertensión arterial secundaria a un APA que se presentó como una masa adrenal incidentalmente descubierta.

Palabras clave:
hipertensión arterial
hiperaldosteronismo primario
incidentaloma adrenal

Adrenal incidentaloma is defined as the casual finding of an adrenal lesion seen during an abdominal imaging study and its incidence in the general population is 4-6%. Benign or malignant lesions, that may be hormonally active or inactive, are found among the possible etiologies. Recent data suggest that the incidence of primary hyperaldosteronism (PHA) in hypertense patients may reach up to 10%, thus representing one of the most frequent causes of secondary high blood pressure. In most of the cases, PHA is caused by an adrenal aldosterone producing adenoma (APA) or bilateral idiopathic hyperplasia. Recent evidence suggests that aldosterone has a direct harmful effect on the cardiovascular system, increasing the incidence of cardiovascular and cerebrovascular events. The clinical case of a 38-year old woman with HBP secondary to APA that presented as an incidentally discovered adrenal mass is presented.

Key words:
high blood pressure
primary hyperaldosteronism
adrenal incidentaloma

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