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Inicio Medicina Clínica May-Thurner syndrome and deep vein thrombosis: A series of 8 patients
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Vol. 156. Issue 12.
Pages 622-624 (June 2021)
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Vol. 156. Issue 12.
Pages 622-624 (June 2021)
Clinical report
May-Thurner syndrome and deep vein thrombosis: A series of 8 patients
Síndrome de May-Thurner y trombosis venosa profunda: estudio de ocho pacientes
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Alejandra García-Garcíaa,b, Crhistian-Mario Oblitasa,b, Francisco Galeano-Vallea,b,c,
Corresponding author
paco.galeano.valle@gmail.com

Corresponding author.
, Andrea Olmos-Nietob, Ana Ortega-Soudantb, Pablo Demelo-Rodrígueza,b,c
a Venous Thromboembolism Unit, Internal Medicine. Hospital General Universitario Gregorio Marañón, Madrid, Spain
b Department of Medicine, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain
c Instituto de investigación sanitaria Gregorio Marañón, Madrid, Spain
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Table 1. Clinical characteristics of patients with deep vein thrombosis and May-Thurner syndrome.
Table 2. Treatment and outcomes.
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Abstract
Objectives

To analyze the prevalence of May-Thurner syndrome (MTS) among patients with deep vein thrombosis (DVT) of left lower limb (LLL), and outcomes after long-term follow-up.

Method

Retrospective observational study that included patients older than 18 diagnosed with acute DVT and MTS.

Results

Among 760 patients diagnosed with DVT in the LLL, 8 patients were diagnosed with MTS (1.05%), with a mean age of 39 years. All patients received long-term anticoagulation, with a mean of 31.9 (±25.2) months. Invasive treatment with pharmaco-mechanical thrombectomy was performed in 5 patients (62.5%). During follow-up (mean of 32.4 months), 25% of patients suffered DVT recurrence. Only 1 case presented major bleeding, and no deaths were registered.

Conclusions

May-Thurner syndrome constitutes a permanent and underdiagnosed risk factor for the development of DVT of LLL. Our findings suggest that long-term anticoagulation therapy might be considered in selected cases.

Keywords:
Deep venous thrombosis
May-Thurner syndrome
Thrombectomy
Anticoagulation
Resumen
Objetivos

Analizar la prevalencia del síndrome de May-Thurner (SMT) en una cohorte de pacientes con trombosis venosa profunda (TVP) en el miembro inferior izquierdo (MII), y las complicaciones durante el seguimiento a largo plazo.

Métodos

Estudio observacional retrospectivo que incluyó a pacientes mayores de 18 años con diagnóstico de TVP en el MII y SMT.

Resultados

Entre los 760 pacientes diagnosticados de TVP en el MII, ocho pacientes fueron diagnosticados de SMT (1,05%), con una media de edad de 39 años. Todos los pacientes recibieron tratamiento anticoagulante a largo plazo, con una media de 31,9 (± 25,2) meses. Se realizó tratamiento invasivo con trombectomía fármaco-mecánica en cinco pacientes (62,5%). Durante el seguimiento (media de 32,4 meses), el 25% de los pacientes sufrieron recurrencia de TVP. Solo se registró un sangrado mayor y no se registraron muertes.

Conclusiones

El síndrome de May-Thurner constituye un factor de riesgo infradiagnosticado y permanente para el desarrollo de TVP en el MII. Nuestros hallazgos sugieren que la anticoagulación a largo plazo podría ser considerada en casos seleccionados.

Palabras clave:
Trombosis venosa profunda
Síndrome de May-Thurner
Trombectomía
Anticoagulación

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