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Inicio Medicina Clínica (English Edition) Daily use of HIV pre-exposure prophylaxis among gay, bisexual and other men who ...
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Vol. 162. Issue 3.
Pages 95-102 (February 2024)
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Vol. 162. Issue 3.
Pages 95-102 (February 2024)
Original article
Daily use of HIV pre-exposure prophylaxis among gay, bisexual and other men who have sex with men in Spain: Prevalence and associated factors
El uso diario de la profilaxis preexposición para el VIH en hombres gais, bisexuales y otros hombres que tienen sexo con hombres en España: prevalencia y factores asociados
Sara Moreno-Garcíaa, M. José Belzab,c,
Corresponding author
mbelza@isciii.es

Corresponding author.
, Carlos Iniestad, Paule González-Reciob,c, David Palmac,e, Luis Sordoc,f, Jose Pulidoc,f, Juan Miguel Guerrasb,c
a Servicio de Medicina Preventiva, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain
b Escuela Nacional de Sanidad, Instituto de Salud Carlos III, Madrid, Spain
c Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
d Sociedad Española Interdisciplinaria del Sida (SEISIDA), Madrid, Spain
e Servicio de Epidemiología, Agencia de Salud Pública de Barcelona, Barcelona, Spain
f Departamento de Salud Pública y Materno-Infantil, Universidad Complutense de Madrid, Madrid, Spain
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Figures (1)
Tables (3)
Table 1. Socio-demographic characteristics according to daily PrEP use in HIV-negative GBMSM men recruited online in Spain, 2020 (n=4692).
Table 2. Sexual behaviours, drugs of abuse, history of HIV testing and sexually transmitted infections according to PrEP use, in HIV-negative GBMSM men recruited online in Spain, 2020 (n=4692).
Table 3. Prevalence and factors associated with daily PrEP use among HIV-negative GBMSM men recruited online in Spain, 2020 (n=4692).
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Abstract
Objective

We aim to estimate the prevalence of daily HIV pre-exposure prophylaxis (PrEP) use six months after public funding approval in Spain and identify associated factors in a national sample of gay, bisexual and other men who have sex with men (GBMSM).

Methods

We analysed 4692 HIV-undiagnosed GBMSM men recruited via an online questionnaire distributed nationally via gay contact apps and websites between May and July 2020. We estimated the proportion of participants using daily PrEP and identified associated factors using Poisson regression with robust variance.

Results

Daily PrEP use was reported by 2.8% of all participants. Daily PrEP use was independently associated with being recruited into community programmes, being older than 30 years, living in a large city, living with men, having condomless anal intercourse with more than 10 sexual partners, using drugs for sex, especially chemsex drugs, and being diagnosed with a sexually transmitted infection.

Conclusions

Six months after PrEP was approved in Spain, the prevalence of daily use is low in a national sample of GBMSM men. There is a need to promote access, demand and interest in PrEP, especially among young GBMSM men, those living in small and medium-sized cities, and those who hide their relationships with other men.

Keywords:
Pre-exposure prophylaxis
HIV
GBMSM
Resumen
Objetivo

Estimar la prevalencia de uso diario de profilaxis pre-exposición (PrEP) frente al VIH seis meses después de aprobarse su financiación pública en España e identificar los factores asociados en una muestra nacional de hombres gais, bisexuales y otros hombres que tienen sexo con hombres (GBHSH).

Material y métodos

Se analizaron 4.692 hombres GBHSH no diagnosticados de VIH reclutados mediante un cuestionario online difundido a nivel nacional a través de apps y webs de contacto gay entre mayo y julio de 2020. Se estimó la proporción de participantes que usaban PrEP diaria y se identificaron factores asociados mediante regresión de Poisson con varianza robusta.

Resultados

El 2,8% (IC95%:2,3–3,3) de los participantes refirió usar PrEP diariamente. El uso diario de PrEP se asoció de forma independiente con: haber sido reclutado en programas comunitarios, ser mayor de 30 años, residir en grandes ciudades, vivir abiertamente su vida sexual con hombres, haber tenido relaciones anales sin preservativo con más de 10 parejas sexuales, haber consumido drogas para sexo, especialmente drogas chemsex, y haber sido diagnosticado de alguna infección de transmisión sexual.

Conclusión

Transcurridos seis meses desde la aprobación de la PrEP en España, se observa una baja prevalencia de uso diario en una muestra nacional de hombres GBHSH. Es necesario promover el acceso, la demanda y el interés por la PrEP, especialmente entre los hombres GBHSH jóvenes, residentes en ciudades pequeñas y medianas y los que ocultan sus relaciones con otros hombres.

Palabras clave:
Profilaxis preexposición
VIH
GBHSH

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