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Inicio Medicina Clínica (English Edition) Neurosarcoidosis: Analysis of a series of 20 patients
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Vol. 155. Issue 7.
Pages 309-312 (October 2020)
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Vol. 155. Issue 7.
Pages 309-312 (October 2020)
Clinical report
Neurosarcoidosis: Analysis of a series of 20 patients
Neurosarcoidosis: análisis de una serie de 20 pacientes
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Lina Carazo Barriosa, Manuel Abarca Costalagob, Ana Hidalgo Condeb, Rocío Arnedo Díez de los Ríosb, Rosa García Portalesc, Guillermina García Martína,
Corresponding author
guillerminagmartin@gmail.com

Corresponding author.
a Servicio de Neurología, Hospital Virgen de la Victoria, Málaga, Spain
b Servicio de Medicina Interna, Hospital Virgen de la Victoria, Málaga, Spain
c Servicio de Reumatología, Hospital Virgen de la Victoria, Málaga, Spain
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Table 1. Epidemiological data of the patients with NS at the Virgen de la Victoria Hospital.
Abstract
Introduction

Neurosarcoidosis is a rare complication of sarcoidosis. There are small series on the condition and very few from Spain. We conducted a retrospective study of neurosarcoidosis in Virgen de la Victoria Hospital over the last 10 years.

Patients and method

the medical records of patients diagnosed with sarcoidosis in our setting in the last 10 years were reviewed.

Results

120 patients with sarcoidosis, 20 patients with probable neurosarcoidosis: 30% at the beginning of the illness, 55% later, 15% had isolated neurosarcoidosis. Forty percent had polyneuropathy, 15% cranial neuropathy, 15% myopathy, 10% hemispheric symptoms.

Others

Headache, myelitis, seizures, confusional syndrome. They were treated with steroids, some of them with immunosuppressive treatment. Seventy-two percent improved or were stabilized. Therefore, neurosarcoidosis prevalence in our hospital was 11%, similar to other published series, with similar features, but polyneuropathy was more frequent. Early diagnosis is very important as prognosis is favourable with treatment.

Keywords:
Retrospective study
Neurosarcoidosis
Prognosis
Sarcoidosis
Cohort
Treatment
Resumen
Introducción

La neurosarcoidosis es una rara complicación de la sarcoidosis. Existen series cortas de pacientes con esta afectación. En España son prácticamente inexistentes. Planteamos realizar un estudio retrospectivo sobre neurosarcoidosis en el hospital Virgen de la Victoria a lo largo de diez años.

Pacientes y métodos

Búsqueda en la base de datos hospitalaria de los pacientes con este diagnóstico en los últimos diez años.

Resultados

120 pacientes con sarcoidosis, de los cuales, 20 pacientes compatibles con neurosarcoidosis probable: 30% fue debut de la enfermedad, 55% ya estaban diagnosticados de sarcoidosis, y 15% tuvieron neurosarcoidosis aislada. El 40% presentaron polineuropatía, 15% neuropatía craneal, 15% miopatía, 10% focalidad SNC.

Otros

Cefalea, mielitis, crisis epiléptica, cuadro confusional. Se trataron con esteroides, y a veces asociaron otros inmunosupresores. El 72% de los casos se estabilizaron o hubo mejoría. Por tanto, la prevalencia de neurosarcoidosis en nuestro hospital es del 11%, parecido a otras series publicadas, con características similares, pero con mayor frecuencia de polineuropatía. El pronóstico de la enfermedad es aceptablemente favorable con tratamiento, por lo que es importante el diagnóstico precoz.

Palabras clave:
Estudio retrospectivo
Neurosarcoidosis
Pronóstico
Sarcoidosis
Serie
Tratamiento

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