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Inicio Medicina Clínica (English Edition) Value of advanced interatrial block in the diagnosis of the ischemic stroke's ae...
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Vol. 159. Issue 6.
Pages 278-282 (September 2022)
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Vol. 159. Issue 6.
Pages 278-282 (September 2022)
Original article
Value of advanced interatrial block in the diagnosis of the ischemic stroke's aetiology: A cohort study
Valor del bloqueo interauricular avanzado en el diagnóstico de la etiología cardioembólica del ictus isquémico: estudio de cohortes
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Jose Maria Vieitez Floreza,
Corresponding author
chemavieitez@gmail.com

Corresponding author.
, Arantxa Sánchez Sánchezb, Rafael Martínez Moyaa, Jaime Masjuan Vallejob,d, Eduardo Franco Díeza, Marta Jimenez-Blanco Bravoa,e, Maria Abellas Sequeirosa, Alvaro Lorente Rosa, Jose Luis Zamorano Gómeza,e, Gonzalo Luis Alonso Salinasa,c
a Cardiology Department, Ramón y Cajal University Hospital, Madrid, Spain
b Neurology Department, Ramón y Cajal University Hospital, Madrid, Spain
c Cardiology Department, University Hospital of Navarra, Pamplona, Spain
d IRYCIS Health Research, Facultad de Medicina, Universidad de Alcalá, Madrid, Spain
e Centro de Investigación en Red de Enfermedades Cardiovasculares (CIBERCV), Spain
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Abstract
Introduction and objectives

Advanced interatrial block has been linked with atrial fibrillation (AF) (Bayes syndrome). On the other hand, the aetiology of the stroke remains unknown in approximately 20–25% of patients admitted due to ischaemic stroke. The aim of this study was to evaluate whether advanced interatrial block and CHADS2-VASC scale is linked to AF in patients admitted due to ischaemic stroke without previous AF history.

Methods

A prospective analysis of consecutive in-hospital patients admitted with ischemic stroke between January/2018 and April/2019 in a stroke hospital was performed. Patients had to be in sinus rhythm at admission and without previous history of AF/atrial flutter. During follow up patients receive the usual care.

Results

A total of 236 patients were included. The median follow-up was 540 days (407–695). 19 patients (8.1%) had advanced interatrial block at admission. Advanced interatrial block was associated with the diagnosis of AF during follow up (5 (26.3%) Vs 21 (9.7%) p=0.027). A CHADS2-VASC score>4 at admission was also associated with AF diagnosis during follow up (23(14.6%) vs 3(3.9%) p=0.009).

Conclusion

This study confirms the association of advanced interatrial block and CHADS2-VASC>4 at admission with the diagnosis of AF during follow up in patients with ischemic stroke. This association could have important implications in patients with ischemic stroke who present advanced interatrial block and without previous history of AF.

Keywords:
Interatrial block
Cerebral infarction
Cardiac embolism
Stroke
Atrial fibrillation
Abbreviations:
AIB
AF
AFL
ECG
TIA
Resumen
Introducción y objetivos

El bloqueo interauricular (BIA) completo se relaciona con el desarrollo de arritmias supraventriculares, especialmente de fibrilación auricular (FA) (síndrome de Bayés). En este trabajo evaluamos la utilidad de este fenómeno para discernir la etiología cardioembólica en los pacientes ingresados por ictus isquémico. También se estudió la relación entre la puntuación en la escala CHADS 2-VA 2 Sc y el desarrollo de FA durante el seguimiento.

Métodos

Análisis prospectivo de pacientes consecutivos ingresados por ictus isquémico entre enero del 2018 y abril del 2019 en un hospital terciario centro de referencia de ictus. Los pacientes incluidos debían de estar en ritmo sinusal en el momento del ingreso y no tener historia previa de FA/flutter auricular. Se realizó el seguimiento mediante las consultas y estudios de rutina, sin intervenir en su manejo habitual.

Resultados

Se incluyó a 236 pacientes. La mediana de seguimiento fue de 540 días (407-695); 19 pacientes (8,1%) presentaron BIA en el electrocardiograma al ingreso. El BIA completo al ingreso se relacionó con el desarrollo posterior de FA (5 [26,3%) vs. 21 [9,7%]; p=0,027). También se observó que un CHADS 2-VA 2 Sc>4 al ingreso se relacionaba con presentar FA durante el seguimiento (23 [14,6%] vs. 3 [3,9%]; p=0,009).

Conclusión

Con este estudio se demuestra por primera vez en pacientes con ictus isquémico que tanto el BIA completo como un CHADS 2-VA 2 Sc>4 se asocian con el desarrollo de FA en el seguimiento. Esta asociación puede tener importantes implicaciones prácticas en el manejo de pacientes ingresados por ictus que presenten BIA completo.

Palabras clave:
Síndrome de Bayés
Bloqueo interauricular
Embolismo cardiaco
Ictus isquémico
Fibrilación auricular

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