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Noteworthy from the family history was the father being recently diagnosed with pulmonary tuberculosis.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The skin biopsy showed the presence of giant cell granulomas, with no caseous necrosis or acid-alcohol fast bacilli, and the PCR and the culture showed positive for <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> complex. The Mantoux intradermal test was positive. Lung involvement was ruled out with a negative chest X-ray and a negative sputum smear microscopy.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The treatment prescribed was isoniazid, rifampin, pyrazinamide, and ethambutol for 2 months, followed by isoniazid and rifampin for 4 months. After one year of follow-up, there was no recurrence, with the skin lesions leaving residual atrophic scars.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The finding of a chronic ulcerated lesion with associated adenopathies requires a broad clinical differential diagnosis, including chancriform syphilis-type lesions, sporotrichosis, nocardiosis, tularemia, atypical mycobacterial infections, or cat scratch disease. The epidemiological history, clinical history, and complementary tests, including skin biopsy with PCR and culture, are key for early diagnosis and treatment that reduce morbidity.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Silvestre Torner N, Imbernón Moya A, Díaz-Delgado Peñas R. Complejo cutáneo tuberculoso primario. 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