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"423" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Alberto Andamoyo Castañeda, Iván Pérez de Pedro, Elisabeth Gómez Moyano, Leandro Martínez Pilar" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Alberto" "apellidos" => "Andamoyo Castañeda" "email" => array:1 [ 0 => "oyomadna@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Iván" "apellidos" => "Pérez de Pedro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Elisabeth" "apellidos" => "Gómez Moyano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "Leandro" "apellidos" => "Martínez Pilar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Regional Universitario de Málaga, Málaga, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Regional Universitario de Málaga, Málaga, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Úlceras cutáneas en paciente con dermatomiositis amiopática anti-MDA5 positivo" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 500 "Ancho" => 750 "Tamanyo" => 44186 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 16-year-old male diagnosed with dermatomyositis in 2017 from the Gottron’s papules on the metacarpophalangeal joints and histologic appearance by biopsy, presented symptoms of asthenia, dyspnoea and loss of 4 kg in 4 weeks. The ANA titer lab report showed 1:160, so treatment was started with prednisone 20 mg/day and tapered for 2 months, as well as mycophenolate mofetil 1,500 mg/morning and 1,000 mg/night with clinical improvement. In 2018, ulcers appeared on the fingertips that required corticosteroid therapy with partial remission. In February 2019 the patient experienced clinical worsening with erythematous-violaceous lesions and ulcers on the fingertips (<a class="elsevierStyleCrossRefs" href="#fig0005">Figs. 1 and 2</a>). Lab tests showed positive anti-MDA5, so treatment was intensified with bosentan, acetylsalicylic acid, prednisone and mycophenolate mofetil with remission of the lesions.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The presence of ulcers on the fingertips in patients diagnosed with dermatomyositis is associated with the presence of positive anti-MDA5 and worsening of the disease.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Andamoyo Castañeda A, Pérez de Pedro I, Gómez Moyano E, Martínez Pilar L. Úlceras cutáneas en paciente con dermatomiositis amiopática anti-MDA5 positivo. 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