array:24 [ "pii" => "S2387020619301974" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.04.015" "estado" => "S300" "fechaPublicacion" => "2019-06-21" "aid" => "4639" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2018" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:517" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775318305591" "issn" => "00257753" "doi" => "10.1016/j.medcli.2018.07.022" "estado" => "S300" "fechaPublicacion" => "2019-06-21" "aid" => "4639" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:517" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 7 "HTML" => 7 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imagen médica</span>" "titulo" => "Síndrome de Madelung" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "517" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Madelung's disease" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 535 "Ancho" => 1000 "Tamanyo" => 111090 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Sara López-García, José Ramón Vizán-Caravaca, Elisabeth García-Cortacero" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Sara" "apellidos" => "López-García" ] 1 => array:2 [ "nombre" => "José Ramón" "apellidos" => "Vizán-Caravaca" ] 2 => array:2 [ "nombre" => "Elisabeth" "apellidos" => "García-Cortacero" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020619301974" "doi" => "10.1016/j.medcle.2019.04.015" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619301974?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318305591?idApp=UINPBA00004N" "url" => "/00257753/0000015200000012/v1_201906070610/S0025775318305591/v1_201906070610/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S2387020619301755" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.08.017" "estado" => "S300" "fechaPublicacion" => "2019-06-21" "aid" => "4622" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:e73" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Syncope: Arrhythmic onset of a metastasis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "e73" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síncope: debut arrítmico de una metástasis" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1137 "Ancho" => 1872 "Tamanyo" => 271865 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Bàrbara Carbonell, Margarida Pujol-López, Rodolfo San Antonio, Sara Vázquez, Rosario J. Perea, Rut Andrea" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Bàrbara" "apellidos" => "Carbonell" ] 1 => array:2 [ "nombre" => "Margarida" "apellidos" => "Pujol-López" ] 2 => array:2 [ "nombre" => "Rodolfo" "apellidos" => "San Antonio" ] 3 => array:2 [ "nombre" => "Sara" "apellidos" => "Vázquez" ] 4 => array:2 [ "nombre" => "Rosario J." "apellidos" => "Perea" ] 5 => array:2 [ "nombre" => "Rut" "apellidos" => "Andrea" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619301755?idApp=UINPBA00004N" "url" => "/23870206/0000015200000012/v1_201906160657/S2387020619301755/v1_201906160657/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2387020619302001" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.04.016" "estado" => "S300" "fechaPublicacion" => "2019-06-21" "aid" => "4674" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2019;152:e71-2" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Fulminant myocardial cryptococcosis in an human immunodeficiency virus infected patient" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e71" "paginaFinal" => "e72" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Criptococosis miocárdica fulminante en un paciente con infección por el virus de la inmunodeficiencia humana" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 931 "Ancho" => 900 "Tamanyo" => 107990 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Silver staining observing the encapsulated yeasts where capsule is not stained with the ink.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Image granted by Dr. Tagmouti Ghita, Anatomical Pathology Service of the Hospital del Mar in Barcelona.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Raquel Bosch-Compte, Yolanda Díaz, Joan Ramon Masclans" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Raquel" "apellidos" => "Bosch-Compte" ] 1 => array:2 [ "nombre" => "Yolanda" "apellidos" => "Díaz" ] 2 => array:2 [ "nombre" => "Joan Ramon" "apellidos" => "Masclans" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775318306444" "doi" => "10.1016/j.medcli.2018.10.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318306444?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619302001?idApp=UINPBA00004N" "url" => "/23870206/0000015200000012/v1_201906160657/S2387020619302001/v1_201906160657/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Madelung's disease" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "517" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Sara López-García, José Ramón Vizán-Caravaca, Elisabeth García-Cortacero" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Sara" "apellidos" => "López-García" ] 1 => array:4 [ "nombre" => "José Ramón" "apellidos" => "Vizán-Caravaca" "email" => array:1 [ 0 => "joserra.vizan@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "Elisabeth" "apellidos" => "García-Cortacero" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Interna, Hospital Santa Ana, Motril, Granada, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de Madelung" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 762 "Ancho" => 1667 "Tamanyo" => 148105 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 61-year-old male, who drinks alcohol 100<span class="elsevierStyleHsp" style=""></span>g/day, was admitted to internal medicine for progressive increase in neck circumference over the course of 8 months caused by soft and painless tumors, which limited the mobility of the neck. He showed no constitutional symptoms, pruritus, profuse sweating, fever and no infectious symptomatology.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a pseudoathletic build and the presence of rubbery, painless, mobile, confluent and bilateral masses in neck, nape and supraclavicular fossa of about 4–5<span class="elsevierStyleHsp" style=""></span>cm (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), and without overlying skin alterations.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Additional tests showed GGT 87<span class="elsevierStyleHsp" style=""></span>IU/l and MCV 102.3<span class="elsevierStyleHsp" style=""></span>fl, with negative serologies, tumor markers and acute phase reactants. The X-ray showed a significant increase in soft tissue in neck and chest (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Finally, the diagnosis was obtained by neck-chest CT where the presence of lymphadenopathies was ruled out and we could notice symmetrical and bilateral intermuscular fat infiltration in neck, suggestive findings of multiple symmetric lipomatosis or Madelung's disease (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">This entity is characterized by subcutaneous fat deposits in neck and shoulders, being more frequent in males (30:1) and, although the etiology is unknown, there is a clear association with chronic alcohol consumption.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: López-García S, Vizán-Caravaca JR, García-Cortacero E. Síndrome de Madelung. Med Clin (Barc). 2019;152:517.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 535 "Ancho" => 1000 "Tamanyo" => 111090 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 762 "Ancho" => 1667 "Tamanyo" => 148105 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015200000012/v1_201906160657/S2387020619301974/v1_201906160657/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015200000012/v1_201906160657/S2387020619301974/v1_201906160657/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619301974?idApp=UINPBA00004N" ]
Journal Information
Share
Download PDF
More article options
Image in medicine
Madelung's disease
Síndrome de Madelung
Sara López-García, José Ramón Vizán-Caravaca
, Elisabeth García-Cortacero
Corresponding author
Servicio de Medicina Interna, Hospital Santa Ana, Motril, Granada, Spain