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"rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 35-year-old male, waiter by profession, with no personal history of interest, who presented with a 5-year history of rash. Initially, diagnosed with atopic dermatitis, he had developed a generalized and pruritic condition, which had been controlled with methotrexate. The patient explained that although the rash on the hands improved substantially, it had continued to spread almost from the start of treatment to the present time. The examination revealed mild hyperkeratosis with diffuse and accentuated desquamation in the folds of both palms, multiple desquamative patches (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a) and dystrophic nails with a whitish-yellow coloration, without periungual inflammation, accompanied by distal onycholysis (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>b). Skin biopsy showed yeast, a fact that was confirmed by culture as <span class="elsevierStyleItalic">C. albicans was isolated.</span> Complete blood count, biochemistry and serologies did not show any abnormalities. After treatment with fluconazole 50 mg/day/for 6 weeks the patient is asymptomatic.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Secondary syphilitic lesions, ringworm, psoriasis, chronic eczema, or even paraneoplastic syndromes can be associated with palmar hyperkeratosis such as the one we report. Candida skin infection usually affects intertriginous areas and rarely other surfaces. In immunocompromised patients and/or humidity conditions, its growth can be enhanced by involving atypical areas, as in our patient.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors declare that they have not received funding to carry out this study.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Pérez-López I, Herrera-García JD, Ruiz-Villaverde R. Hiperqueratosis palmar en paciente inmunodeprimido. 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