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He reported using no medication for about 2 years.</p><p id="par0010" class="elsevierStylePara elsevierViewall">On physical examination, tenderness, swelling, and nodule with deposits of solid, yellow-white chalky material were observed on the lateral right midfoot (arrow) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Computed tomography (CT) showed severe erosive changes (arrowhead) and extensive tophaceous deposits (asterisk) of the foot and knee (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B–D). The blood test highlighted the elevation of uric acid and acute phase reactants. Aspirated synovial fluid from the right knee joint contained monosodium urate crystals. Gram staining and culture were negative.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The diagnosis of chronic destructive tophaceous gout was established, and treatment with allopurinol and colchicine was initiated. Furthermore, surgical excision and debridement of the tophi was performed. He was advised to avoid purine-rich foods and alcohol. Six months following initial presentation, clinical and laboratory improvement was observed.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The development of intraarticular tophi is characterized by chronic destructive articular involvement and is extremely difficult to treat. The appearance of intraarticular tophi on CT is quite specific. 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Journal Information
Image in medicine
Tophaceous gout with bone destruction
Gota tofácea con destrucción ósea
Sadettin Uslu
Department of Rheumatology, Ömer Halisdemir University Bor Physical Medicine and Rehabilitation, Training and Research Hospital, Niğde, Turkey