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Follicular mycosis fungoides, a rare and aggressive variant
Micosis fungoide folicular, una variante infrecuente y agresiva
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The existence of clearly defined follicular papules is appreciated in some areas (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The extension study (blood count, general biochemistry, LDH, beta-2 microglobulin, needle aspiration of bone marrow, proteinogram and PET-CT) showed no extracutaneous involvement, establishing the diagnosis of mycosis fungoides (MF) stage <span class="elsevierStyleSmallCaps">I</span>B (T2b, N0, M0, B0). Histopathology showed infiltrated dermis by a lymphoproliferative process distributed at perivascular and periadnexal level (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Hair follicles were infiltrated with the presence of strong positive mucin for alcian blue (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). The immunohistochemistry study showed positivity for CD3, CD5 and CD7, with deletion of CD2 and partly of CD4. Follicular mycosis fungoides (FMF) or folliculotropic is a variant of MF characterized by the presence of follicular infiltrates affecting head and neck, preferentially. FMF is considered to have a worse prognosis, behaving similarly or equivalently to the tumour stage of classical MF (stage IIB).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Ruiz-Villaverde R, Pérez-López I, Garrido-Colmenero C, Aneiros-Fernández J. Micosis fungoide folicular, una variante infrecuente y agresiva. 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