Image in medicine
Methamizole-induced agranulocytosis
Agranulocitosis secundaria a tratamiento con metamizol
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Laboratory tests showed neutropenia and peripheral blood smear (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) showing agranulocytosis (one white blood cell in smear) without any other blood dyscrasias. Methimazole treatment was suspended, empiric coverage was initiated with broad-spectrum antibiotic treatment (amikacin and piperacillin<span class="elsevierStyleHsp" style=""></span>+<span class="elsevierStyleHsp" style=""></span>tazobactam) and colony stimulating factors were administered. Agranulocytosis by methimazole is a type B side effect (independent of the effect of the medication), that is potentially serious (close to 10% mortality) and with an estimated incident rate on the population of between 7.3 and 9.3 cases per million per year.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Pedrazas López D, de Pablo Márquez B, García Font D, Sánchez García E. Agranulocitosis secundaria a tratamiento con metamizol. 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