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Complications of sickle cell disease
Complicaciones de la anemia falciforme
Servicio de Radiodiagnóstico, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
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A MRI showed a bone infarction in the proximal femoral diaphysis (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A, arrow). The patient had anemia but other biochemical data were unremarkable. The patient developed fever, chest pain and decreased oxygen saturation (93%). A condensation appeared in the chest radiography (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B, arrow). A bronchoscopy with lavage was performed.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Microbiological tests were positive for Influenza B, but otherwise negative. A thorax CT scan showed pulmonary consolidation involving the lower pulmonary lobe (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C and D, arrow), cardiomegaly (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C, star) and pleural effusion (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D, star). The diagnosis was acute chest syndrome, a common complication of infection and of vasocclusive crisis in sickle cell disease. Hypoxia associated to alterations in ventilation-perfusion relationship (infection, fat embolus, atelectasis, bronchospasm, pain, etc.) triggers falciformation of the red cells, that in turn causes vascular occlusion, ischemia and vascular injury. The patient received opioid analgesics, hyperhydration, antibiotics, antivirals, transfusion, oxygen and physiotherapy and was finally discharged.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Peña Gomez E, Vidal Trueba H. Complicaciones de la anemia falciforme. 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