Image in medicine
Localized cutaneous leishmaniasis
Leishmaniasis cutánea localizada
Miguel Ángel Flores-Terry
, Manuela López-Nieto, Rafael Cruz-Conde de Boom, Jose Antonio Garrido-Martín
Corresponding author
Servicio de Dermatología y Venereología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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On examination, an infiltrated, slightly desquamative erythematous plaque of 3<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.5<span class="elsevierStyleHsp" style=""></span>cm was observed, with ulceration and central scab (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A, circle). A biopsy of the non-ulcerated site was performed, showing areas of parakeratosis, mild spongiosis, lymphocyte exocytosis and isolated necrotic keratinocytes in the epidermis, and a perivascular and perifollicular lymphohistiocytic infiltrate with plasma cells in the dermis. The PCR for <span class="elsevierStyleItalic">Leishmaniasis infantum</span> was positive. No other lesions were observed and there was no systemic involvement, so the patient continued his previous treatment; the lesion was treated with intralesional meglumine antimoniate (glucantime 1500<span class="elsevierStyleHsp" style=""></span>mg/5<span class="elsevierStyleHsp" style=""></span>ml) during 6 cycles, with resolution at 3 months (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Leishmaniasis is an infection caused by a protozoan of the <span class="elsevierStyleItalic">Leishmania</span> genus and transmitted by a vector (phlebotome female mosquitoes). Localized cutaneous leishmaniasis is the most frequent cutaneous clinical form, which usually begins as papules that progress to nodules and/or plaques with soft and/or ulcerated centers.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Flores-Terry MÁ, López-Nieto M, Cruz-Conde de Boom R, Garrido-Martín JA. Leishmaniasis cutánea localizada. Med Clin (Barc). 2017;149:e1.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1204 "Ancho" => 2667 "Tamanyo" => 607460 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000014900000001/v1_201707230028/S2387020617303856/v1_201707230028/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000014900000001/v1_201707230028/S2387020617303856/v1_201707230028/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020617303856?idApp=UINPBA00004N" ]
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