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Proliferative verrucous leukoplakia of the tongue
Leucoplasia verrucosa proliferativa de la lengua
Paolo Cariati
, Ana Belen Marin Fernandez, Jose Fernandez Solis
Corresponding author
Servicio de Cirugía Oral y Maxilofacial, Hospital Universitario Virgen de las Nieves, Granada, Spain
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Its aetiology is unknown, although it is related to tobacco, papillomavirus, fungi and certain oncogenes. It has a higher prevalence in women in the sixth decade. It can develop in any area of the oral cavity. Its clinical presentation is characterized by solitary or multifocal white homogenous plaques that slowly extend in continuous fashion or in separate areas, accompanied by diffuse verrucous, papillary and erythematous changes (<a class="elsevierStyleCrossRefs" href="#fig0005">Figs. 1 and 2</a>). Due to its multifocal and variable presentation, it is necessary to perform several incisional biopsies for its established diagnosis. The treatment is very variable and controversial. Despite the wide variety of therapeutic options available (surgery, laser therapy, photodynamic therapy, chemotherapy, chemoprevention and radiotherapy), none seems to be satisfactory, with surgery being the first choice in most cases. The irreversibility of the lesions and the high rate of malignant transformation make it a disease that is difficult to control and that requires close long-term follow-up.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 65-year-old man with PVL of the tongue (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). The diagnosis was confirmed by multiple incisional biopsy. Due to the large extension, the patient was treated with partial sequential resections with an electric scalpel.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Cariati P, Marin Fernandez AB, Fernandez Solis J. Leucoplasia verrucosa proliferativa de la lengua. 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