Image in medicine
Diagnosis of vasculitis with 18F-FDG PET/CT study in patient with fever of unknown origin
Diagnóstico de vasculitis en estudio 18F-FDG PET/TC en paciente con fiebre de origen desconocido
Juan Jose Martin-Marcuartu
, Jose Antonio Lojo-Ramirez, Victor Manuel Pachón-Garrudo, José Manuel Jimenez-Hoyuela
Corresponding author
Servicio de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Sevilla, Spain
Read
4
Timeswas read the article
2
Total PDF
2
Total HTML
Share statistics
array:24 [ "pii" => "S2387020618305357" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.12.001" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4500" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2018" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:125" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775318302355" "issn" => "00257753" "doi" => "10.1016/j.medcli.2018.03.034" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4500" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:125" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 18 "formatos" => array:2 [ "HTML" => 10 "PDF" => 8 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imagen médica</span>" "titulo" => "Diagnóstico de vasculitis en estudio <span class="elsevierStyleSup">18</span>F-FDG PET/TC en paciente con fiebre de origen desconocido" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "125" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Diagnosis of vasculitis with <span class="elsevierStyleSup">18</span>F-FDG PET/CT study in patient with fever of unknown origin" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1667 "Ancho" => 1400 "Tamanyo" => 115672 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Juan Jose Martin-Marcuartu, Jose Antonio Lojo-Ramirez, Victor Manuel Pachón-Garrudo, José Manuel Jimenez-Hoyuela" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Juan Jose" "apellidos" => "Martin-Marcuartu" ] 1 => array:2 [ "nombre" => "Jose Antonio" "apellidos" => "Lojo-Ramirez" ] 2 => array:2 [ "nombre" => "Victor Manuel" "apellidos" => "Pachón-Garrudo" ] 3 => array:2 [ "nombre" => "José Manuel" "apellidos" => "Jimenez-Hoyuela" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020618305357" "doi" => "10.1016/j.medcle.2018.12.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305357?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318302355?idApp=UINPBA00004N" "url" => "/00257753/0000015200000003/v1_201901250619/S0025775318302355/v1_201901250619/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2387020618305369" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.12.002" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4505" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:e17" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Skin necrosis after septic shock" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "e17" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Necrosis cutánea tras <span class="elsevierStyleItalic">shock</span> séptico" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 847 "Ancho" => 1583 "Tamanyo" => 195390 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Cristina García Harana, Inés Fernández Canedo, Magdalena de Troya Martín" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Cristina" "apellidos" => "García Harana" ] 1 => array:2 [ "nombre" => "Inés" "apellidos" => "Fernández Canedo" ] 2 => array:2 [ "nombre" => "Magdalena" "apellidos" => "de Troya Martín" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775318302458" "doi" => "10.1016/j.medcli.2018.04.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318302458?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305369?idApp=UINPBA00004N" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305369/v1_201901290746/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2387020618305485" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.05.051" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4550" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2019;152:e15" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Clinical impact of cardiopulmonary exercise testing in hypertrophic cardiomyopathy" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "e15" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Impacto clínico del test de ejercicio cardiopulmonar en la miocardiopatía hipertrófica" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alberto Dominguez-Rodriguez, Nestor Baez-Ferrer, Pedro Abreu-Gonzalez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Alberto" "apellidos" => "Dominguez-Rodriguez" ] 1 => array:2 [ "nombre" => "Nestor" "apellidos" => "Baez-Ferrer" ] 2 => array:2 [ "nombre" => "Pedro" "apellidos" => "Abreu-Gonzalez" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305485?idApp=UINPBA00004N" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305485/v1_201901290746/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Diagnosis of vasculitis with <span class="elsevierStyleSup">18</span>F-FDG PET/CT study in patient with fever of unknown origin" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "125" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Juan Jose Martin-Marcuartu, Jose Antonio Lojo-Ramirez, Victor Manuel Pachón-Garrudo, José Manuel Jimenez-Hoyuela" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Juan Jose" "apellidos" => "Martin-Marcuartu" "email" => array:1 [ 0 => "jjmarcuartu@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Jose Antonio" "apellidos" => "Lojo-Ramirez" ] 2 => array:2 [ "nombre" => "Victor Manuel" "apellidos" => "Pachón-Garrudo" ] 3 => array:2 [ "nombre" => "José Manuel" "apellidos" => "Jimenez-Hoyuela" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Sevilla, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Diagnóstico de vasculitis en estudio <span class="elsevierStyleSup">18</span>F-FDG PET/TC en paciente con fiebre de origen desconocido" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1097 "Ancho" => 668 "Tamanyo" => 36460 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 68-year-old patient admitted because of a three-month long low-grade fever (37.4–37.7<span class="elsevierStyleHsp" style=""></span>°<span class="elsevierStyleSmallCaps">C)</span>, malaise and asthaenia. His analytical tests of note showed: VSG: 70 and CRP: 60 and negative ANA and ANCA. A PET/CT with <span class="elsevierStyleSup">18</span>F-FDG was performed as the fever was of unknown origin.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Images at 60<span class="elsevierStyleHsp" style=""></span>min postinjection of <span class="elsevierStyleSup">18</span>F-FDG show pathological increase of radiotracer uptake and linear morphology (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) that in the fusion images correspond to the arterial walls of the supra-aortic trunks, subclavian arteries, ascending aorta, arch and descending aorta (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) as well as bilateral common iliac and right internal arteries, with a SUVmax of 6.93 and compatible with the inflammatory process of the great vessels (compatible with the diagnosis of vasculitis).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The patient started treatment with corticosteroids with significant clinical improvement. They do not currently manifest symptoms and are in follow-up through consultations.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The <span class="elsevierStyleSup">18</span>F-FDG PET/CT is a technique that has shown its usefulness in the diagnosis of vasculitis with a specificity of 60–92% and a sensitivity of 88–100%. It allows us to assess the extent of the disease and response to treatment, as well as guides the diagnosis when atypical symptoms exist (weight loss, malaise, fever of unknown origin).</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martin-Marcuartu JJ, Lojo-Ramirez JA, Pachón-Garrudo VM, Jimenez-Hoyuela JM. Diagnóstico de vasculitis en estudio <span class="elsevierStyleSup">18</span>F-FDG PET/TC en paciente con fiebre de origen desconocido. Med Clin (Barc). 2019;152:125.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1097 "Ancho" => 668 "Tamanyo" => 36460 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1195 "Ancho" => 1002 "Tamanyo" => 70539 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305357/v1_201901290746/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015200000003/v1_201901290746/S2387020618305357/v1_201901290746/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305357?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2023 March | 2 | 2 | 4 |
