Editorial article
Anorectal sexually transmitted infections. An infradiagnosticated epidemic
Infecciones de transmisión sexual anorrectales. Una epidemia infradiagnosticada
División de Enfermedades Infecciosas, Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain
Read
5
Timeswas read the article
3
Total PDF
2
Total HTML
Share statistics
array:24 [ "pii" => "S2387020618305436" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.07.017" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4584" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2018" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:102-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775318304342" "issn" => "00257753" "doi" => "10.1016/j.medcli.2018.07.002" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4584" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2019;152:102-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 20 "formatos" => array:2 [ "HTML" => 14 "PDF" => 6 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>" "titulo" => "Infecciones de transmisión sexual anorrectales. Una epidemia infradiagnosticada" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "102" "paginaFinal" => "103" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Anorectal sexually transmitted infections. An infradiagnosticated epidemic" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alfonso Cabello, Miguel Górgolas" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Alfonso" "apellidos" => "Cabello" ] 1 => array:2 [ "nombre" => "Miguel" "apellidos" => "Górgolas" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020618305436" "doi" => "10.1016/j.medcle.2018.07.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305436?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318304342?idApp=UINPBA00004N" "url" => "/00257753/0000015200000003/v1_201901250619/S0025775318304342/v1_201901250619/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S2387020618305461" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.03.037" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4517" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Med Clin. 2019;152:104-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical report</span>" "titulo" => "Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Report of two cases" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "104" "paginaFinal" => "106" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hiperplasia neuroendocrina difusa pulmonar idiopática: estudio de dos casos" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1869 "Ancho" => 2482 "Tamanyo" => 439747 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">(a) Hematoxylin and eosin staining technique showing the mucosa of a terminal bronchiole with cilia in the epithelium and neuroendocrine cells (asterisk). (b) The same area showing positivity for CD 56 with immunohistochemistry that corresponds with a neuroendocrine cell hyperplasia (asterisk, objective magnification 60×). (c) Paratracheal lymph node of case number 1 stained with hematoxylin and eosin technique showing a little focus of neuroendocrine epithelial cells that corresponds with a metastatic typical carcinoid marked with an asterisk (objective magnification 20×). Insert: immunohistochemical technique using cytokeratins, which highlights the metastatic neuroendocrine cells. (d) CT of case number 2. We can observe a subcentimeter nodule in the middle lobe (arrow) and a bilateral mosaic pattern.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Eva García-Fontán, Montserrat Blanco Ramos, Jose Soro García, Rommel Carrasco, Miguel Ángel Cañizares, Ana González Piñeiro" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Eva" "apellidos" => "García-Fontán" ] 1 => array:2 [ "nombre" => "Montserrat" "apellidos" => "Blanco Ramos" ] 2 => array:2 [ "nombre" => "Jose Soro" "apellidos" => "García" ] 3 => array:2 [ "nombre" => "Rommel" "apellidos" => "Carrasco" ] 4 => array:2 [ "nombre" => "Miguel Ángel" "apellidos" => "Cañizares" ] 5 => array:2 [ "nombre" => "Ana" "apellidos" => "González Piñeiro" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305461?idApp=UINPBA00004N" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305461/v1_201901290746/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2387020618305333" "issn" => "23870206" "doi" => "10.1016/j.medcle.2018.02.033" "estado" => "S300" "fechaPublicacion" => "2019-02-01" "aid" => "4452" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Med Clin. 2019;152:98-101" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Brief report</span>" "titulo" => "Infecciones de transmisi¢n sexual con afectaci¢n anorrectal: agentes causales, coinfecciones, infecci¢n por el VIH y conductas de riesgo" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "98" "paginaFinal" => "101" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Infecciones de transmisión sexual con afectación anorrectal: agentes causales, coinfecciones, infección por el VIH y conductas de riesgo" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Daniel Morgado-Carrasco, Mercè Alsina Gibert, Jordi Bosch Mestres, Miriam Álvarez Martínez, José Luís Blanco Arévalo, Irene Fuertes de Vega" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Daniel" "apellidos" => "Morgado-Carrasco" ] 1 => array:2 [ "nombre" => "Mercè" "apellidos" => "Alsina Gibert" ] 2 => array:2 [ "nombre" => "Jordi" "apellidos" => "Bosch Mestres" ] 3 => array:2 [ "nombre" => "Miriam" "apellidos" => "Álvarez Martínez" ] 4 => array:2 [ "nombre" => "José Luís" "apellidos" => "Blanco Arévalo" ] 5 => array:2 [ "nombre" => "Irene" "apellidos" => "Fuertes de Vega" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775318301532" "doi" => "10.1016/j.medcli.2018.02.014" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318301532?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305333?idApp=UINPBA00004N" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305333/v1_201901290746/en/main.assets" ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial article</span>" "titulo" => "Anorectal sexually transmitted infections. An infradiagnosticated epidemic" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "102" "paginaFinal" => "103" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Alfonso Cabello, Miguel Górgolas" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Alfonso" "apellidos" => "Cabello" "email" => array:1 [ 0 => "acabello@fjd.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Miguel" "apellidos" => "Górgolas" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "División de Enfermedades Infecciosas, Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Infecciones de transmisión sexual anorrectales. Una epidemia infradiagnosticada" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Recently, antigenic and molecular diagnostic techniques have improved our ability to detect the pathogens responsible for various infections.<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">1</span></a> This has been accompanied by an increase in the incidence and prevalence of some entities, making us doubt, at times, whether they are really increasing or we have simply increased our diagnostic capacity.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Sexually transmitted infections (STIs) are an example of the diseases where these two realities have converged. Despite this, there is no author who doubts the sustained increase of most STIs in recent decades.<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">2,3</span></a> This increase has occurred mainly in certain groups, such as men who have sex with men (MSM) and sex workers.<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">3–5</span></a> The causes are multiple and varied, however, numerous authors agree that two of the causes are a lower perception of the risk of acquiring the human immunodeficiency virus (HIV) – mainly due to the introduction of highly effective antiretroviral treatments – and changes in habits and practices.<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">6</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The close relationship between HIV and other STIs is well known; they share transmission mechanisms, risk factors and incidence curves in certain groups.<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">2,7,8</span></a> MSM represent the highest rate of new HIV diagnoses reported in our country,<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">9</span></a> and it is not surprising that they are the majority in the study presented by the authors.<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">10</span></a> This study presents a series of cases of STIs with anorectal involvement (STI-AR), all occurring in MSM, to outline a focused and very useful perspective on anorectal disease, whose diagnosis requires not only clinical suspicion, but also detection through anal inspection and a microbiological study of the rectal samples. About 80% of the subjects diagnosed had symptoms of proctitis, which was more than 10% of the global cohort of patients who were attended to during this period. These figures show the importance and frequency of proctitis in the MSM group and the need to understand it so it can be dealt with effectively.<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">11</span></a> The diagnosis of proctitis can be done through symptoms, based on a good anamnesis and a correlation with risk factors. Furthermore, exploration by conventional anoscopy or proctoscopy provides very useful information for the establishment of an empirical treatment<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">12</span></a> and can offer adequate samples for study.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Not being aware of this disease favours a delay in diagnosis and treatment<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">13</span></a> given the similarities between the rectal lesions that appear with ulcerative colitis and lymphogranuloma venereum (LGV)<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">14</span></a> or that of a severe proctitis due to LGV or gonococcus and a haemorrhoid condition or anal fissure.</p><p id="par0025" class="elsevierStylePara elsevierViewall">New molecular tests have made it possible to more accurately detect the main causative agents, often with a single exudate sample, facilitating and simplifying the empirical treatment subsequently prescribed.<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">15</span></a> Furthermore, they improve the early detection of asymptomatic cases, preventing progression of the lesions and epidemic transmission.</p><p id="par0030" class="elsevierStylePara elsevierViewall">The study carried out by Morgado-Carrasco et al.<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">10</span></a> is worth noting as it offers very useful data for the prescription of empirical antibiotic treatment when there is a suspicion of anal or perianal infection. This is done according to symptoms, ensuring the simplification of international guideline recommendations, whose objective seems to be more aimed at covering all pathogens.<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">11</span></a> The authors recommend giving empirical coverage against anal LGV when clinical suspicion is high (anal ulcer and associated proctitis), even when the <span class="elsevierStyleItalic">Chlamydia trachomatis</span> serotype L1-3 diagnostic technique is not available. Meanwhile, the presence of an anal ulcer without associated proctitis would indicate a possible lues, a disease responsible for up to 20% of the diagnoses.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Finally, focusing on sexual habits and epidemiological aspects is essential, as also pointed out by Morgado-Carrasco et al. Certain sexual practices, including so-called chemsex<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">16</span></a> (the combination of drugs and sex in order to facilitate or lengthen the latter), have been associated with the MSM group, unprotected sexual relationships and having multiple partners. In addition, several studies describe its establishment mainly in large cities and European capitals (as this study does), and that participants are educated subjects with relevant purchasing power.<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">17</span></a> There is also a high percentage of foreign patients who are well trained and have a high social-economic level, resulting in them being easily able to change residence while continuing their personal and professional development without dispensing with certain sexual practices or habits. The different meeting events arranged by these groups, also pointed out by the authors, entail a great mobilisation of people, especially within the European framework, exponentially increasing the possibilities of STI-AR transmission.<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">18</span></a> We should remember this when new outbreaks are reported in our context,<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">19</span></a> assuming that the chances of them reaching large cities are high, whether in the form of outbreaks or multiresistant variants of some specific germs.<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">20</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">STI-AR is a frequent entity in MSM, mainly in subjects with HIV infection. The sexual habits and the mobilisation of this group by these events facilitate their dispersion throughout the main European cities. Studies such as those carried out by Morgado-Carrasco et al. can help to focus more precisely on the empirical treatment of these infections, while also assist in discovering other unknown diseases, or those that are underestimated by many doctors, but very present among those patients they often attend to.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Cabello A, Górgolas M. Infecciones de transmisión sexual anorrectales. Una epidemia infradiagnosticada. Med Clin (Barc). 2019;152:102–103.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0105" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Performance of Anyplex™ II multiplex real-time PCR for the diagnosis of seven sexually transmitted infections: comparison with currently available methods" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H.S. Choe" 1 => "D.S. Lee" 2 => "S.J. Lee" 3 => "S.H. Hong" 4 => "D.C. Park" 5 => "M.K. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ijid.2013.07.011" "Revista" => array:6 [ "tituloSerie" => "Int J Infect Dis" "fecha" => "2013" "volumen" => "17" "paginaInicial" => "e1134" "paginaFinal" => "e1140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24095619" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0110" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High prevalence of anorectal chlamydial infection in HIV-infected men who have sex with men in Switzerland" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Dang" 1 => "K. Jaton-Ogay" 2 => "M. Flepp" 3 => "H. Kovari" 4 => "J.M. Evison" 5 => "J. Fehr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/644740" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2009" "volumen" => "49" "paginaInicial" => "1532" "paginaFinal" => "1535" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19848599" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0115" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical diagnostic and therapeutic aspects of 221 consecutive anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections among men who have sex with men" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Lourtet Hascoet" 1 => "M. Dahoun" 2 => "M. Cohen" 3 => "E. Pommaret" 4 => "B. Pilmis" 5 => "M. Lemarchand" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ijid.2018.03.016" "Revista" => array:6 [ "tituloSerie" => "Int J Infect Dis" "fecha" => "2018" "volumen" => "71" "paginaInicial" => "9" "paginaFinal" => "13" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29608959" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0120" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "When people with HIV get syphilis: triple jeopardy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.S. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.olq.0000204530.19762.e4" "Revista" => array:6 [ "tituloSerie" => "Sex Transm Dis" "fecha" => "2006" "volumen" => "33" "paginaInicial" => "149" "paginaFinal" => "150" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16505743" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0125" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sexually transmitted infections: challenges ahead" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Unemo" 1 => "C.S. Bradshaw" 2 => "J.S. Hocking" 3 => "H.J. de Vries" 4 => "S.C. Francis" 5 => "D. Mabey" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S1473-3099(17)30310-9" "Revista" => array:6 [ "tituloSerie" => "Lancet Infect Dis" "fecha" => "2017" "volumen" => "17" "paginaInicial" => "e235" "paginaFinal" => "e279" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28701272" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0130" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prácticas y percepción del riesgo en hombres con infección por el virus de la inmunodeficiencia humana que tienen sexo con otros hombres" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Fernández de Mosteyrín" 1 => "M. del Val Acebrón" 2 => "T. Fernández de Mosteyrín" 3 => "M.L. Fernández Guerrero" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eimc.2013.04.017" "Revista" => array:6 [ "tituloSerie" => "Enferm Infecc Microbiol Clin" "fecha" => "2013" "volumen" => "32" "paginaInicial" => "219" "paginaFinal" => "224" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23896320" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0135" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.T. Fleming" 1 => "J.N. Wasserheit" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Sex Transm Infect" "fecha" => "1999" "volumen" => "75" "paginaInicial" => "3" "paginaFinal" => "17" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10448335" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0140" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Grupo de Expertos del Grupo de Estudio de Sida de la SEIMC (GESIDA), Secretaría del Plan Nacional Sobre el Sida (SPNS), Grupo de Estudio de ITS de la SEIMC (GEITS), Grupo Español para la Investigación de las Enfermedades de Transmisión Sexual de la Academia Española de Dermatología y Venereología y de la Sociedad Española de Infectología Pediátrica (SEIP). Documento de consenso sobre diagnóstico y tratamiento de las infecciones de transmisión sexual en adultos, niños y adolescentes. Marzo 2017." ] ] ] 8 => array:3 [ "identificador" => "bib0145" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Dirección General de Salud Pública, Calidad e Innovación. Vigilancia epidemiológica del VIH y sida en España 2016. Actualización 30 de junio de 2017. Sistema de información sobre nuevos diagnósticos VIH. Registro Nacional de Casos de Sida 2017. Available at: <a id="intr0010" class="elsevierStyleInterRef" href="https://www.msssi.gob.es/ciudadanos/enfLesiones/enfTransmisibles/sida/vigilancia/InformeVIH_SIDA_2017_NOV2017.pdf">https://www.msssi.gob.es/ciudadanos/enfLesiones/enfTransmisibles/sida/vigilancia/InformeVIH_SIDA_2017_NOV2017.pdf</a> [accessed 05.07.18]." ] ] ] 9 => array:3 [ "identificador" => "bib0150" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sexually transmitted diseases of the anus and rectum: causal agents, coinfections, HIV infection and high-risk sexual behaviour" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D. Morgado-Carrasco" 1 => "M. Alsina Gibert" 2 => "J. Bosch Mestres" 3 => "M. Álvarez Martínez" 4 => "J. Blanco Arévalo" 5 => "I. Fuertes de Vega" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:2 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "2018" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0155" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "2013 European guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.J. De Vries" 1 => "A. Zingoni" 2 => "J.A. White" 3 => "J.D. Ross" 4 => "A. Kreuter" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1177/0956462413516100" "Revista" => array:6 [ "tituloSerie" => "Int J STD AIDS" "fecha" => "2014" "volumen" => "25" "paginaInicial" => "465" "paginaFinal" => "474" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24352129" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0160" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Anorectal lymphogranuloma venereum in Madrid" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Cabello Úbeda" 1 => "R. Fernández Roblas" 2 => "R. García Delgado" 3 => "L. Martínez García" 4 => "F. Sterlin" 5 => "M.L. Fernández Guerrero" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/OLQ.0000000000000459" "Revista" => array:6 [ "tituloSerie" => "Sex Transm Dis" "fecha" => "2016" "volumen" => "43" "paginaInicial" => "414" "paginaFinal" => "419" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27322040" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0165" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphogranuloma venereum proctocolitis: a silent endemic disease in men who have sex with men in industrialised countries" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. Martin-Iguacel" 1 => "J.M. Llibre" 2 => "H. Nielsen" 3 => "E. Heras" 4 => "L. Matas" 5 => "R. Lugo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s10096-010-0959-2" "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Microbiol Infect Dis" "fecha" => "2010" "volumen" => "29" "paginaInicial" => "917" "paginaFinal" => "925" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20509036" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0170" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Proctitis as the clinical presentation of lymphogranuloma venereum, a re-emerging disease in developed countries" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. López-Vicente" 1 => "D. Rodríguez-Alcalde" 2 => "L. Hernández-Villalba" 3 => "D. Moreno-Sánchez" 4 => "M. Lumbreras-Cabrera" 5 => "C. Barros-Aguado" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Esp Enferm Dig" "fecha" => "2014" "volumen" => "106" "paginaInicial" => "59" "paginaFinal" => "62" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24689719" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0175" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Usefulness of a novel multiplex real-time PCR assay for the diagnosis of sexually-transmitted infections" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Fernández" 1 => "E. Martró" 2 => "V. González" 3 => "V. Saludes" 4 => "E. Bascuñana" 5 => "C. Marcó" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eimc.2015.10.014" "Revista" => array:6 [ "tituloSerie" => "Enferm Infecc Microbiol Clin" "fecha" => "2016" "volumen" => "34" "paginaInicial" => "471" "paginaFinal" => "476" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26706392" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0180" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "Available at: <a class="elsevierStyleInterRef" target="_blank" id="intr0015" href="http://www.sigmaresearch.org.uk/chemsex">www.sigmaresearch.org.uk/chemsex</a>" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Chemsex study: drug use in sexual settings among gay and bisexual men in Lambeth, Southwark and Lewisham" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Bourne" 1 => "D. Reid" 2 => "F. Hickson" 3 => "S. Torres Rueda" 4 => "P. Weatherburn" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2014" "editorial" => "London School of Hygiene & Tropical Medicine" "editorialLocalizacion" => "London" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0185" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sexualized drug use (chemsex) is associated with high-risk sexual behaviors and sexually transmitted infections in HIV-positive men who have sex with men: data from the U-SEX GESIDA 9416 study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. González-Baeza" 1 => "H. Dolengevich-Segal" 2 => "I. Pérez-Valero" 3 => "A. Cabello" 4 => "M.J. Téllez" 5 => "J. Sanz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "AIDS Patient Care STDS" "fecha" => "2018" "volumen" => "32" "paginaInicial" => "112" "paginaFinal" => "118" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0190" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of sexual network connectivity and antimicrobial drug use on antimicrobial resistance in <span class="elsevierStyleItalic">Neisseria gonorrhoeae</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.R. Kenyon" 1 => "I.S. Schwartz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3201/eid2407.172104" "Revista" => array:6 [ "tituloSerie" => "Emerg Infect Dis" "fecha" => "2018" "volumen" => "24" "paginaInicial" => "1195" "paginaFinal" => "1203" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29912682" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0195" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hepatitis A outbreak among men who have sex with men (MSM) predominantly linked with the EuroPride, the Netherlands, July 2016 to February 2017" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G.S. Freidl" 1 => "G.J. Sonder" 2 => "L.P. Bovée" 3 => "I.H. Friesema" 4 => "G.G. van Rijckevorsel" 5 => "W.L. Ruijs" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2807/1560-7917.ES.2017.22.8.30468" "Revista" => array:5 [ "tituloSerie" => "Euro Surveill" "fecha" => "2017" "volumen" => "22" "paginaInicial" => "30468" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28251892" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0200" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.R. Harris" 1 => "M.J. Cole" 2 => "G. Spiteri" 3 => "L. Sánchez-Busó" 4 => "D. Golparian" 5 => "S. Jacobsson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S1473-3099(18)30225-1" "Revista" => array:6 [ "tituloSerie" => "Lancet Infect Dis" "fecha" => "2018" "volumen" => "18" "paginaInicial" => "758" "paginaFinal" => "768" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29776807" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015200000003/v1_201901290746/S2387020618305436/v1_201901290746/en/main.assets" "Apartado" => array:4 [ "identificador" => "46797" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Editorial article" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015200000003/v1_201901290746/S2387020618305436/v1_201901290746/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020618305436?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2023 March | 2 | 3 | 5 |
