Statistics

 array:23 [
  "pii" => "S2387020619302141"
  "issn" => "23870206"
  "doi" => "10.1016/j.medcle.2019.04.017"
  "estado" => "S300"
  "fechaPublicacion" => "2019-07-05"
  "aid" => "4656"
  "copyright" => "Elsevier España, S.L.U.. All rights reserved"
  "copyrightAnyo" => "2018"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Med Clin. 2019;153:46"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0025775318305967"
      "issn" => "00257753"
      "doi" => "10.1016/j.medcli.2018.10.003"
      "estado" => "S300"
      "fechaPublicacion" => "2019-07-05"
      "aid" => "4656"
      "copyright" => "Elsevier España, S.L.U."
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Med Clin. 2019;153:46"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 5
        "HTML" => 5
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Imagen m&#233;dica</span>"
        "titulo" => "Xantomas y xantelasmas en colangitis biliar primaria"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "46"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Xanthomas and xanthelasmas in primary biliary cholangitis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:6 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 1122
                "Ancho" => 750
                "Tamanyo" => 115120
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Pablo A&#46; &#193;lvarez Aguilar, Sof&#237;a Angulo Mora"
            "autores" => array:2 [
              0 => array:2 [
                "nombre" => "Pablo A&#46;"
                "apellidos" => "&#193;lvarez Aguilar"
              ]
              1 => array:2 [
                "nombre" => "Sof&#237;a"
                "apellidos" => "Angulo Mora"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2387020619302141"
          "doi" => "10.1016/j.medcle.2019.04.017"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619302141?idApp=UINPBA00004N"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318305967?idApp=UINPBA00004N"
      "url" => "/00257753/0000015300000001/v1_201906160629/S0025775318305967/v1_201906160629/es/main.assets"
    ]
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2387020619302815"
    "issn" => "23870206"
    "doi" => "10.1016/j.medcle.2018.09.019"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-05"
    "aid" => "4650"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Med Clin. 2019;153:45"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>"
      "titulo" => "Erythematous nodule in a child"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "45"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "N&#243;dulo eritematoso en un ni&#241;o"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0010"
          "etiqueta" => "Fig&#46; 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 675
              "Ancho" => 900
              "Tamanyo" => 106268
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mar&#237;a Da&#241;ino Garc&#237;a, Juli&#225;n Conejo-Mir, Teresa Zulueta Dorado, Jos&#233; Bernabeu-Wittel"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mar&#237;a"
              "apellidos" => "Da&#241;ino Garc&#237;a"
            ]
            1 => array:2 [
              "nombre" => "Juli&#225;n"
              "apellidos" => "Conejo-Mir"
            ]
            2 => array:2 [
              "nombre" => "Teresa"
              "apellidos" => "Zulueta Dorado"
            ]
            3 => array:2 [
              "nombre" => "Jos&#233;"
              "apellidos" => "Bernabeu-Wittel"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0025775318305906"
        "doi" => "10.1016/j.medcli.2018.09.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775318305906?idApp=UINPBA00004N"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619302815?idApp=UINPBA00004N"
    "url" => "/23870206/0000015300000001/v1_201906260821/S2387020619302815/v1_201906260821/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>"
    "titulo" => "Xanthomas and xanthelasmas in primary biliary cholangitis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "46"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Pablo A&#46; &#193;lvarez Aguilar, Sof&#237;a Angulo Mora"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "Pablo A&#46;"
            "apellidos" => "&#193;lvarez Aguilar"
            "email" => array:1 [
              0 => "pabloalvarez83@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Sof&#237;a"
            "apellidos" => "Angulo Mora"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Medicina Interna&#44; Hospital M&#233;xico&#44; San Jos&#233;&#44; Costa Rica"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Xantomas y xantelasmas en colangitis biliar primaria"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:6 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1122
            "Ancho" => 750
            "Tamanyo" => 115120
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 58-year-old patient was admitted to the internal medicine ward with history of asthenia&#44; adynamia&#44; weight loss of 10<span class="elsevierStyleHsp" style=""></span>kg in 5 months &#40;weight at admission&#58; 36&#46;5<span class="elsevierStyleHsp" style=""></span>kg&#41;&#44; night pruritus and appearance of yellowish plaques on face &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41; and neck &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; No history of smoking&#44; alcoholism or familial dyslipidemia was evident&#46; No history of liver disease was revealed&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">A ferropenic anemia was documented &#40;hemoglobin&#58; 9&#46;8<span class="elsevierStyleHsp" style=""></span>g&#47;dL&#44; hematocrit&#58; 32&#46;9&#37;&#41;&#44; normal kidney function and in the liver profile showed cholestatic pattern &#40;AST&#58; 69<span class="elsevierStyleHsp" style=""></span>IU&#47;L&#59; ALT&#58; 62<span class="elsevierStyleHsp" style=""></span>IU&#47;L&#58; total bilirubin&#58; 1&#46;6<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#58; direct bilirubin&#58; 0&#46;9<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; alkaline phosphatase&#58; 1180<span class="elsevierStyleHsp" style=""></span>IU&#47;L&#44; gamma-glutamyl transferase&#58; 551<span class="elsevierStyleHsp" style=""></span>IU&#47;L&#41;&#46; Serotypes for hepatotropic viruses were negative and the cholesterol level was 560<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; LDL&#58; 497<span class="elsevierStyleHsp" style=""></span>mg&#47;dL and erythrosedimentation&#58; 144<span class="elsevierStyleHsp" style=""></span>mm&#47;h&#46; The presence of hepatic masses was ruled out with sonography and magnetic resonance&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Antinuclear and antimitochondrial antibodies were positive &#40;11&#46;4 and &#62;100<span class="elsevierStyleHsp" style=""></span>U&#47;mL&#44; respectively&#41;&#44; so the diagnosis of primary biliary cholangitis was made&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The confirmatory biopsy showed mononuclear inflammation in some portal spaces with absence of small bile ducts&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; &#193;lvarez Aguilar PA&#44; Angulo Mora S&#46; Xantomas y xantelasmas en colangitis biliar primaria&#46; Med Clin &#40;Barc&#41;&#46; 2019&#59;153&#58;46&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 500
            "Ancho" => 750
            "Tamanyo" => 53416
          ]
        ]
      ]
      1 => array:6 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1122
            "Ancho" => 750
            "Tamanyo" => 115120
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/23870206/0000015300000001/v1_201906260821/S2387020619302141/v1_201906260821/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "51820"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Images in medicine"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015300000001/v1_201906260821/S2387020619302141/v1_201906260821/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020619302141?idApp=UINPBA00004N"
]