Letter to the Editor
About polypharmacy in older adults
Acerca de la polifarmacia en adultos mayores
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As researchers with a special interest in the elderly and acute heart failure (AHF), we would like to highlight some aspects that we consider of interest and that are meant to reinforce the above-mentioned article. The authors find a significant consumption of medicines in the non-institutionalised population aged 65 and over in Spain, continuing the trend observed in recent years of increasing prevalence of polypharmacy over time, and where the factors most associated with polypharmacy are mainly the number of chronic health problems and dependence for basic activities of daily living (BADLs). The <span class="elsevierStyleItalic">Epidemiology of Acute Heart Failure in Emergency Departments</span> (EAHFE)<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> registry currently contains 13,791 episodes of AHF, collected consecutively in the 5 inclusion periods carried out to date (in 2007, 2009, 2011, 2014 and 2016) and in which 41 Spanish emergency departments have participated, with an average age of 80 years (SD 10), 55% women. In our series, 87.3% were older than or equal to 65 years: 12,042 patients. The prevalence of polypharmacy in our registry was 47.7% and that of hyperpolypharmacy 1%, in line with the data shown by these authors when they analyse the sensitivity considering the possible combination therapy for 2 chronic diseases such as hypertension and diabetes: prevalence of polypharmacy 37.5% and hyperpolypharmacy 2.5%. In the same way, our registry showed that polypharmacy was positively associated with dependence for BADLs<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> (Barthel index less than 60 points, p < 0.001). Thus, our results support those described by Gutiérrez-Valencia et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>, where the elderly population has a significant consumption of drugs, and that this increases significantly when associated with different chronic diseases<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a>, and shows that functional deficit is one of the most important factors linked to polypharmacy, facts that are also essential for understanding drug consumption patterns in elderly people with heart failure and that will allow us to plan and evaluate future healthcare actions<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Jacob J, Peña B, Herrero-Puente P. Acerca de la polifarmacia en adultos mayores. Med Clin (Barc). 2021;156:309–309.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalencia de polifarmacia y factores asociados en adultos mayores en España: datos de la Encuesta Nacional de Salud 2017" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Gutiérrez-Valencia" 1 => "P. Aldaz Herce" 2 => "E. Lacalle-Fabo" 3 => "B. Contreras Escámez" 4 => "B. Cedeno-Veloz" 5 => "N. Martínez-Velilla" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.medcli.2018.12.013" "Revista" => array:6 [ "tituloSerie" => "Med Clin (Barc)." 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