Image in medicine
Intrathoracic synovial sarcoma
Sarcoma sinovial intratorácico
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Physical examination revealed a pulmonary systolic murmur. A chest X-ray showed an enlarged cardiac silhouette (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Thoracic CT angiography showed a mediastinal mass of 142 × 156 × 158 mm (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>, arrow), deforming and infiltrating the left atrium (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>, asterisk), producing mild stenosis of the pulmonary trunk and pulmonary veins.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Crude needle biopsy was compatible with synovial sarcoma with presence of SYT gene translocation (18q11.2). Concomitant neoadjuvant therapy was started with adriamycin and ifosfamide, and radical radiotherapy, with the intention of evaluating surgery at the end of treatment.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Intrathoracic synovial sarcoma is a rare malignant mesenchymal tumour, occurring mainly in young adults, accounting for less than 0.5% of all lung tumours.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Detection of the SYT (18q11.2) gene translocation is highly specific for the diagnosis of synovial sarcoma.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Surgery is the treatment of choice for localised disease; chemotherapy and radiotherapy are the treatments of choice for locally advanced and metastatic tumours.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: González Sans D, Aleman C, Cabanzo L. Sarcoma sinovial intratorácico. 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