Image in medicine
Cushing disease
Enfermedad de Cushing
María Carrera-Morodo
, Andrea Larrañaga Cabrera
Corresponding author
Centro de Salud La Marina, SAP Esquerra Barcelona, Institut Catalá de la Salut, Barcelona, Spain
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In the context of the COVID-19 pandemic, blood tests were requested and confirmed a worsening of glycaemic control. One year later, the patient complained of palpitations and pain in the right leg. Examination revealed fat accumulation in the bitemporal and supraclavicular regions, hirsutism, facial hyperpigmentation, and thinning of the lower limbs (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">A CBC was requested with 24-h urinary free cortisol (341.8<span class="elsevierStyleHsp" style=""></span>μg/24<span class="elsevierStyleHsp" style=""></span>h, NV 12.8–82.5<span class="elsevierStyleHsp" style=""></span>μg/24<span class="elsevierStyleHsp" style=""></span>h), suppression with 1<span class="elsevierStyleHsp" style=""></span>mg dexamethasone (9.21<span class="elsevierStyleHsp" style=""></span>μg/dL, NV<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>1.8<span class="elsevierStyleHsp" style=""></span>μg/dL) and adrenocorticotropic hormone (ACTH) determination (97<span class="elsevierStyleHsp" style=""></span>pg/mL, NV 10–60<span class="elsevierStyleHsp" style=""></span>pg/dL) confirmed the diagnosis of endogenous ACTH-dependent Cushing's syndrome. Cranial magnetic resonance imaging (MRI) showed a thickening of the pituitary gland, with heterogeneous enhancement and a cystic area inside of 1.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleHsp" style=""></span>mm, which led to a diagnosis of Cushing’s disease.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Carrera-Morodo M, Larrañaga Cabrera A. Enfermedad de Cushing. 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