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Letter to the Editor
Bilateral serous retinal detachment in pregnancy-induced hypertension
Desprendimiento de retina bilateral seroso en un caso de hipertensión inducida por el embarazo
Francisco M. Hermoso-Fernándeza,
Corresponding author
framaherfer@gmail.com

Corresponding author.
, Cristina Palma Conesab, Carmen Gonzalez-Gallardoa
a Department of Ophthalmology, Hospital Universitario San Cecilio, 18016 Granada, Spain
b Department of Pediatrics, Hospital Universitario San Cecilio, 18016 Granada, Spain
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41; Arrows A&#58; Detachment in the posterior pole&#46; &#40;B&#41; Arrows B&#58; Residual pigmentary changes &#40;Elschnig spots&#41;&#46; &#40;C&#41; On the left RE and on the right LE&#46; Arrow A&#58; sensorineural detachment&#59; Arrow B&#58; detachment of the pigment epithelium&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Pregnancy-induced hypertension &#40;PIH&#41; is believed to cause acute retinal pigment epitheliopathy due to choroidal ischemia&#46; It has been also demonstrated that nonperfusion of the choriocapillaris can cause necrosis of the overlying retinal pigment epithelium &#40;RPE&#41;&#44; which leads to the breakdown of the outer blood&#8211;retinal barrier and the development of serous retinal detachment &#40;SRD&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 31 years old woman who presented blurry vision in both eyes a few hours after the delivery&#46; In the systemic exploration a peripartum eclampsia was detected&#46; A nuclear magnetic resonance was performed with suggestive findings of small acute ischemic lesion in left caudate nucleus that during the follow up over the next three months&#44; were normalized without any sequels&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Ophthalmologist exploration revealed&#58; visual acuity &#40;VA&#41; in his right eye &#40;RE&#41; was 0&#46;2 and 0&#46;12 in his left eye &#40;LE&#41;&#46; Intra-ocular pressure &#40;IOP&#41; was 8 and 6<span class="elsevierStyleHsp" style=""></span>mmHg in RE and LE respectively&#46; Fundoscopy examination showed a bilateral serous retinal detachment associated with choroidal detachment &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; OCT revealed a neuro-sensory detachment with cystoid macular edema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The visual field showed a superior temporal peripheral scotoma&#44; in agreement with the lower peripheral zone where the retinal detachment is finally found before complete resorption&#46; The patient was treated with labetalol 200<span class="elsevierStyleHsp" style=""></span>mg&#47;8<span class="elsevierStyleHsp" style=""></span>h&#44; aspirin 100<span class="elsevierStyleHsp" style=""></span>mg&#47;24<span class="elsevierStyleHsp" style=""></span>h and omeprazole 20<span class="elsevierStyleHsp" style=""></span>mg&#47;24<span class="elsevierStyleHsp" style=""></span>h&#46; Treatment with corticosteroids was proposed&#58; oral prednisone 30<span class="elsevierStyleHsp" style=""></span>mg per day&#44; dexamethasone eye drops every six hours and topical dexamethasone ointment twice a day with the aim of increasing IOP and correcting ocular hypotonia caused by choroidal detachment&#46; An enhancement of VA &#40;RE<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#44; LE<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;8&#41; was observed in recent checkups and there was also a spontaneous resorption of the subretinal fluid and resolution of retinal detachment&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Regarding the visual sequelae of the patient&#44; it is worth highlighting a slight alteration in VA as well as poor color vision&#44; due to the involvement of the cones in the macula and the fovea as a result of hypertrophy of the RPE and strongly correlated with a lack of underlying outer segment regeneration&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> In addition&#44; there was a reduced visual field due to the presence of scotomas&#44; a consequence of several ischemic points that translated into definitive lesions of peripheral photoreceptors&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">PIH is believed to cause acute retinal pigment epitheliopathy due to choroidal ischemia&#46; Endothelial damage of the choroidal vasculature can also lead to fibrinoid necrosis of the choroidal arterioles with choriocapillaris occlusion&#46; Other studies have also demonstrated that nonperfusion of the choriocapillaris can cause necrosis of the overlying RPE&#44; which leads to the breakdown of the outer blood&#8211;retinal barrier and the development of SRD&#46; In the case of our patient&#44; despite the fact that it is a case of late-onset eclampsia&#44; cases in which it is assumed&#44; as described in the literature the imbalance between angiogenic factors is not generated&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> However&#44; the ischemic lesions found both at the central level &#40;nucleus putamen&#41; as well as the lesions at the ophthalmological level support the theory that it is a HELLP syndrome characterized by thrombotic microangiopathy&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The principal management of retinal detachment in pre-eclampsia is conservative and involves treating the underlying condition&#46; After delivery&#44; the sub-retinal fluid is reabsorbed and the visual acuity returns within weeks&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> Although retinal detachments have previously been related to preeclampsia&#44; both choroidal detachments with a marked drop in intraocular pressure and retinal cystic edema that we observed in our patient have not been described in other cases published in the literature&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> On the other hand&#44; the use of ocular hypotensive treatment is usually described in retinal and choroidal detachments to achieve the application of said ocular layers&#46; But&#44; hypotension and therefore choroidal detachments would have been aggravated&#46; Therefore&#44; it was decided to use only corticosteroids&#44; both systemic and topical&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Clinicians should be aware of these ocular manifestations and careful ophthalmological and neurological evaluation should be carried out along with neuroimaging to ascertain the various causes of blindness in pregnancy&#46; The prognosis is usually good&#44; especially with cortical blindness where the loss of vision is transient&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical approval</span><p id="par0045" class="elsevierStylePara elsevierViewall">Informed consent for publication of clinical details and&#47;or images was obtained from the patient&#46; Ethics approval is not applicable&#46; Written informed consent was acquired&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Funding</span><p id="par0050" class="elsevierStylePara elsevierViewall">No funds have been received for this study&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">We have no conflicts of interest to disclose&#46;</p></span></span>"
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Article information
ISSN: 23870206
Original language: English
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es en pt

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