Image in medicine
Neck cutaneous metastasis of gastric signet ring cell carcinoma
Metastasis cutánea de un carcinoma gástrico de células en anillo de sello
a Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Xi’an Medical University, No. 48 Feng Hao West Road, Xi’an, Shaanxi 710077, China
b Department of Pathology, First Affiliated Hospital of Xi’an Medical University, No. 48 Feng Hao West Road, Xi’an, Shaanxi 710077, China
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Three years earlier, the patient underwent total gastrectomy with Roux-en-Y esophagojejunostomy for gastric signet ring cell carcinoma (GSRCC) and received two cycles of chemotherapy with fluorouracil, paclitaxel, and oxaliplatin. Thereafter, he has been treated with Traditional Chinese Medicine. However, the patient did not seek medical advice for a painless neck mass that had been growing over the past 14 months. Physical examination revealed a uneven surface mass measuring 9.5<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>5.5<span class="elsevierStyleHsp" style=""></span>cm in the neck of the patient, which resembled elephantiasis with no tenderness, along with neck lymph node enlargement (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Enhanced magnetic resonance imaging of the neck mass showed a significantly enhanced solid mass invading the skin and subcutaneous tissue (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Enhanced computed tomography of the chest and abdomen showed no visceral metastases. A punch biopsy was performed on the neck mass and histopathological analysis identified cutaneous metastasis from GSRCC. However, the patient refused chemotherapy and only received Traditional Chinese Medicine treatment. At 5-month follow-up, the patient died. Cutaneous metastasis is a uncommon manifestation of solid tumors, and often considered to be incurable in the late stage of advanced gastric cancer and associated with poor prognosis.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0010" class="elsevierStylePara elsevierViewall">None declared.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">None of the authors have any conflict of interest to disclose.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflict of interest" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1121 "Ancho" => 1676 "Tamanyo" => 260708 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 839 "Ancho" => 1676 "Tamanyo" => 112574 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000016000000011/v1_202306121221/S2387020623001870/v1_202306121221/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000016000000011/v1_202306121221/S2387020623001870/v1_202306121221/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020623001870?idApp=UINPBA00004N" ]
