metricas
covid
Buscar en
Medicina Clínica (English Edition)
Toda la web
Inicio Medicina Clínica (English Edition) Harlequin phenomenon in a newborn
Journal Information

Statistics

Follow this link to access the full text of the article

Image in medicine
Harlequin phenomenon in a newborn
Fenómeno de arlequín en recién nacida
Ana Román Fernández
Corresponding author
anarofdz@gmail.com

Corresponding author.
, Leonor Bardallo Cruzado, Jessica Gómez Ávila, Susana León Carretero
Servicio de Neonatología, Hospital Universitario Virgen Macarena, Sevilla, Spain
Read
Not available
Times
was read the article
Total PDF
Total HTML
Share statistics
 array:24 [
  "pii" => "S2387020624000056"
  "issn" => "23870206"
  "doi" => "10.1016/j.medcle.2023.05.029"
  "estado" => "S300"
  "fechaPublicacion" => "2024-02-09"
  "aid" => "6353"
  "copyright" => "Elsevier España, S.L.U.. All rights reserved"
  "copyrightAnyo" => "2023"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Med Clin. 2024;162:144"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0025775323004049"
      "issn" => "00257753"
      "doi" => "10.1016/j.medcli.2023.05.025"
      "estado" => "S300"
      "fechaPublicacion" => "2024-02-09"
      "aid" => "6353"
      "copyright" => "Elsevier España, S.L.U."
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Med Clin. 2024;162:144"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Imagen m&#233;dica</span>"
        "titulo" => "Fen&#243;meno de arlequ&#237;n en reci&#233;n nacida"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "144"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Harlequin phenomenon in a newborn"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:6 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 933
                "Ancho" => 873
                "Tamanyo" => 94405
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Ana Rom&#225;n Fern&#225;ndez, Leonor Bardallo Cruzado, Jessica G&#243;mez &#193;vila, Susana Le&#243;n Carretero"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Ana"
                "apellidos" => "Rom&#225;n Fern&#225;ndez"
              ]
              1 => array:2 [
                "nombre" => "Leonor"
                "apellidos" => "Bardallo Cruzado"
              ]
              2 => array:2 [
                "nombre" => "Jessica"
                "apellidos" => "G&#243;mez &#193;vila"
              ]
              3 => array:2 [
                "nombre" => "Susana"
                "apellidos" => "Le&#243;n Carretero"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2387020624000056"
          "doi" => "10.1016/j.medcle.2023.05.029"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020624000056?idApp=UINPBA00004N"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775323004049?idApp=UINPBA00004N"
      "url" => "/00257753/0000016200000003/v1_202402020520/S0025775323004049/v1_202402020520/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2387020624000135"
    "issn" => "23870206"
    "doi" => "10.1016/j.medcle.2023.06.049"
    "estado" => "S300"
    "fechaPublicacion" => "2024-02-09"
    "aid" => "6385"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Med Clin. 2024;162:145"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>"
      "titulo" => "Superinfected scabies"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "145"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Sarna sobreinfectada"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1048
              "Ancho" => 1034
              "Tamanyo" => 195823
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Emilio Berna-Rico, Sandra Chamorro-Tojeiro, Alfonso P&#233;rez-Gonz&#225;lez, Bibiana P&#233;rez-Garc&#237;a"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Emilio"
              "apellidos" => "Berna-Rico"
            ]
            1 => array:2 [
              "nombre" => "Sandra"
              "apellidos" => "Chamorro-Tojeiro"
            ]
            2 => array:2 [
              "nombre" => "Alfonso"
              "apellidos" => "P&#233;rez-Gonz&#225;lez"
            ]
            3 => array:2 [
              "nombre" => "Bibiana"
              "apellidos" => "P&#233;rez-Garc&#237;a"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020624000135?idApp=UINPBA00004N"
    "url" => "/23870206/0000016200000003/v2_202402160843/S2387020624000135/v2_202402160843/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2387020624000081"
    "issn" => "23870206"
    "doi" => "10.1016/j.medcle.2023.08.008"
    "estado" => "S300"
    "fechaPublicacion" => "2024-02-09"
    "aid" => "6429"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46;"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Med Clin. 2024;162:142-3"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "The right to be&#44; forgotten for patients and professionals in Spain"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "142"
          "paginaFinal" => "143"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "El derecho al olvido para pacientes y profesionales en Espa&#241;a"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Miguel Antonio Lasheras-P&#233;rez, Javier L&#243;pez-Davia, Blanca Unamuno-Bustos"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Miguel Antonio"
              "apellidos" => "Lasheras-P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "L&#243;pez-Davia"
            ]
            2 => array:2 [
              "nombre" => "Blanca"
              "apellidos" => "Unamuno-Bustos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0025775323005766"
        "doi" => "10.1016/j.medcli.2023.08.011"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775323005766?idApp=UINPBA00004N"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020624000081?idApp=UINPBA00004N"
    "url" => "/23870206/0000016200000003/v2_202402160843/S2387020624000081/v2_202402160843/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>"
    "titulo" => "Harlequin phenomenon in a newborn"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "144"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Ana Rom&#225;n Fern&#225;ndez, Leonor Bardallo Cruzado, Jessica G&#243;mez &#193;vila, Susana Le&#243;n Carretero"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Ana"
            "apellidos" => "Rom&#225;n Fern&#225;ndez"
            "email" => array:1 [
              0 => "anarofdz@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Leonor"
            "apellidos" => "Bardallo Cruzado"
          ]
          2 => array:2 [
            "nombre" => "Jessica"
            "apellidos" => "G&#243;mez &#193;vila"
          ]
          3 => array:2 [
            "nombre" => "Susana"
            "apellidos" => "Le&#243;n Carretero"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Neonatolog&#237;a&#44; Hospital Universitario Virgen Macarena&#44; Sevilla&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Fen&#243;meno de arlequ&#237;n en reci&#233;n nacida"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 933
            "Ancho" => 873
            "Tamanyo" => 94405
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Term newborn with hypothermia undergoing treatment in the context of hypoxic-ischaemic encephalopathy&#46; On the third day of life&#44; she presented with well-defined skin changes&#44; with one side of the body plethoric and the other pale &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; They became self-limiting after 5&#8239;min and were repeated hours later on the contralateral side of the body&#44; with no other symptoms &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">This phenomenon called harlequin syndrome is related to sympathetic autonomic dysfunction due to hypothalamic functional immaturity&#44; producing capillary vasodilatation and vasoconstriction&#46; The idiopathic cause is the most common and may occur in healthy newborns&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Other possible causes include central nervous system involvement&#44; such as hypoxia&#44; meningitis&#44; hypothalamic and brainstem lesions&#44; and treatment with anaesthetics or prostaglandins&#46; It usually occurs between the second and fifth day and resolves spontaneously&#44; with several episodes occurring in a 24-h period&#46; It should not be confused with harlequin ichthyosis&#44; the most severe variant of congenital ichthyosis&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">After 8 days&#44; the patient had tonic-clonic seizures&#44; requiring several anticonvulsant drugs&#46; Brain MRI showed white matter involvement&#44; right caudate and bilateral ventricular haemorrhage&#46; It later evolved into West syndrome&#46; Therefore&#44; this phenomenon may be an indication of a severe central nervous system disorder&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical considerations</span><p id="par0025" class="elsevierStylePara elsevierViewall">We&#44; the authors of the manuscript&#44; declare that we have obtained the informed consent of the patient&#8217;s parents for the use of images for teaching purposes or for the dissemination of scientific knowledge&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Funding</span><p id="par0030" class="elsevierStylePara elsevierViewall">No funding has been received for this work&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">None of the authors have any conflict of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:3 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Ethical considerations"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Funding"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Conflict of interest"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 933
            "Ancho" => 681
            "Tamanyo" => 94931
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 933
            "Ancho" => 873
            "Tamanyo" => 94405
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/23870206/0000016200000003/v2_202402160843/S2387020624000056/v2_202402160843/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "51820"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Images in medicine"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/23870206/0000016200000003/v2_202402160843/S2387020624000056/v2_202402160843/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020624000056?idApp=UINPBA00004N"
]
Article information
ISSN: 23870206
Original language: English
The statistics are updated each day

Follow this link to access the full text of the article

es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos