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Vol. 25. Issue 7.
Pages 401-408 (January 2010)
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Vol. 25. Issue 7.
Pages 401-408 (January 2010)
Editorial
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Advances in the Prevention of Cerebral Ischaemia Due to Atrial Fibrillation
Avances en la prevención de la isquemia cerebral por fibrilación auricular
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A. Gil Núñez
Unidad de Ictus, H.G.U. Gregorio Marañón, Madrid, Spain
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Abstract
Introduction

Stroke and atrial fibrillation (AF) are a real vascular epidemic, and the consequences are disastrous. The most common complication of AF is stroke.

Background

The correct aetiological diagnosis of stroke is essential for adequate prevention. The percentage of cryptogenic ischaemic strokes is far too high and the detection of AF needs to be improved. Cardio-embolic cerebral ischaemia due to AF is preventable, however due to medical inertia, the lack of compliance by the patient, and the problems with oral vitamin K antagonist anticoagulants, means that many patients with AF are at risk of suffering from a stroke.

Conclusions

The significant recent advances with drugs such as dronedarone and dabigatran, provide real hope for an improvement in its prevention, and for this reason neurologists must know about them.

Keywords:
Stroke
Atrial fibrillation
Prevention
Dronedarone
Dabigatran
Resumen
Introducción

El ictus y la fibrilación auricular (FA) son una verdadera epidemia vascular, y sus consecuencias son catastróficas. La complicación más común y devastadora de la FA es el ictus.

Desarrollo

El diagnóstico etiológico correcto del ictus es esencial para poder realizar una prevención adecuada. El porcentaje de ictus isquémicos criptogénicos es demasiado elevado, y es preciso mejorar la detección de la FA. La isquemia cerebral cardioembólica por FA es prevenible, pero la inercia médica, la falta de adherencia del paciente y los problemas de los anticoagulantes orales antagonistas de la vitamina K hacen que muchos pacientes con FA estén en riesgo de sufrir una isquemia cerebral.

Conclusiones

Los relevantes avances recientes con fármacos como la dronedarona y el dabigatrán abren una esperanza real para mejorar su prevención y pronto se reflejarán en las guías terapéuticas de prevención y, por lo tanto, los neurólogos debemos conocerlos.

Palabras clave:
Ictus
Fibrilación auricular
Prevención
Dronedarona
Dabigatrán
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Copyright © 2010. Sociedad Española de Neurología
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