Corresponding author at: Complejo Asistencial de Segovia, Valladolid, Spain.
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(A) T2-weighted sagittal slice. (B) Gadolinium-enhanced sagittal slice.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "D. López de Mota Sánchez, L. Maure Blesa, M.T. Montojo Villasanta, A. Herranz Bárcenas" "autores" => array:4 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "López de Mota Sánchez" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Maure Blesa" ] 2 => array:2 [ "nombre" => "M.T." "apellidos" => "Montojo Villasanta" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Herranz Bárcenas" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2667049624000188?idApp=UINPBA00004N" "url" => "/26670496/0000000400000003/v2_202409090816/S2667049624000188/v2_202409090816/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S2667049624000139" "issn" => "26670496" "doi" => "10.1016/j.neurop.2024.100157" "estado" => "S300" "fechaPublicacion" => "2024-07-01" "aid" => "100157" "copyright" => "Sociedad Española de Neurología" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:8 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Immune encephalitis/meningitis, cerebral vasculitis, or HANDL syndrome following SARS-CoV-2 infection" "tienePdf" => "en" "tieneTextoCompleto" => "en" "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Finsterer, A.S. MohanaSundaram, F. Scorza" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Finsterer" ] 1 => array:2 [ "nombre" => "A.S." "apellidos" => "MohanaSundaram" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Scorza" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2667049624000139?idApp=UINPBA00004N" "url" => "/26670496/0000000400000003/v2_202409090816/S2667049624000139/v2_202409090816/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Raccoon sign" "tieneTextoCompleto" => true "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Lorena Caballero Sánchez, Claudia Gómez López de San Román, Amelia Mendoza Rodríguez" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Lorena Caballero" "apellidos" => "Sánchez" "email" => array:1 [ 0 => "lorenacaballeros24@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cr0005" ] ] ] 1 => array:2 [ "nombre" => "Claudia Gómez López" "apellidos" => "de San Román" ] 2 => array:2 [ "nombre" => "Amelia Mendoza" "apellidos" => "Rodríguez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Neurología, Complejo Asistencial de Segovia, Segovia, Spain" "identificador" => "af0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author at: Complejo Asistencial de Segovia, Valladolid, Spain." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "f0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 620 "Ancho" => 827 "Tamanyo" => 113886 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Raccoon sign. Bilateral periorbital ecchymosis, sparing the palpebral tarsus, manifesting 2<span class="elsevierStyleHsp" style=""></span>days after head trauma.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="p0005" class="elsevierStylePara elsevierViewall">Dr. Editor,</p><p id="p0010" class="elsevierStylePara elsevierViewall">Raccoon eyes is a clinical sign characterised by the presence of uni- or bilateral periorbital ecchymosis that manifests 2–3<span class="elsevierStyleHsp" style=""></span>days after head trauma, which is associated with basilar skull fracture. Periorbital ecchymosis does not typically affect the superior tarsus, as the orbital septum hinders blood extravasation.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a><span class="elsevierStyleSup">,</span><a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">2</span></a> Uni- or bilateral presence of this sign may present a positive-predictive value for basilar skull fracture between 70% and 90%, particularly when the fracture is located frontally.<a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">2</span></a><span class="elsevierStyleSup">,</span><a class="elsevierStyleCrossRef" href="#bb0015"><span class="elsevierStyleSup">3</span></a> In contrast to this sign, the periorbital haematoma colloquially known as black eye would be described as the uni- or bilateral periorbital ecchymosis that frequently manifests in the first 24<span class="elsevierStyleHsp" style=""></span>h after a facial trauma, which may affect the whole eyelid, and is not associated with basilar skull fracture.</p><p id="p0015" class="elsevierStylePara elsevierViewall">We report the case of a patient with raccoon sign and discuss multiple aetiologies that may be associated with this sign.</p><p id="p0020" class="elsevierStylePara elsevierViewall">Our patient is a 55-year-old man with no relevant medical history who suffered an accidental fall leading to posterior head trauma. He did not lose consciousness. The patient reported mild occipital headache with oppressive pain in the injured area and haematoma at the vertex, and non-specific, non-vertigo dizziness. He attended the emergency department 2<span class="elsevierStyleHsp" style=""></span>days after the accident due to increased headache intensity, sleepiness, and bilateral periorbital haematomas.</p><p id="p0025" class="elsevierStylePara elsevierViewall">During the examination, the patient showed somnolence but it was easy to keep him focused. He was oriented to time, space, and person. Glasgow Coma Scale score was 15/15. The patient presented no neck rigidity and preserved conjugate eye movement. He presented a haematoma in the posterior medial frontal region, as well as bilateral palpebral haematomas, sparing the pretarsal area (<a class="elsevierStyleCrossRef" href="#f0005">Fig. 1</a>). We also observed abrasion in the medial posterior parietal area. The patient displayed no otorrhoea or nasal secretion. He did not present haemotympanum or retroauricular haematoma. No other relevant pathological findings were observed in the neurological examination.</p><elsevierMultimedia ident="f0005"></elsevierMultimedia><p id="p0030" class="elsevierStylePara elsevierViewall">A cranial CT scan showed haemorrhagic contusions in the bilateral frontal basal region, with an associated small subarachnoid haemorrhagic component, and medial frontal fracture, with no pneumocephalus or paranasal sinus occupation.</p><p id="p0035" class="elsevierStylePara elsevierViewall">A series of clinical signs may lead physicians to suspect basilar skull fractures, such as CSF rhinorrhoea, CSF otorrhoea, retroauricular ecchymosis (also known as Battle sign, which is particularly associated with fracture of the temporal bone), haemotympanum, and periorbital ecchymosis (raccoon sign), the finding observed in our patient.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a> This fact is especially relevant as neuroimaging studies do not always show such fractures; thus, clinical findings are more informative than complementary tests.</p><p id="p0040" class="elsevierStylePara elsevierViewall">In these cases, examination is essential for diagnosis and, consequently, for appropriate management, as specific treatment may be needed for some diseases associated with basilar skull fractures, such as CSF fistula, carotid-cavernous fistula, brain abscesses, or meningitis.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a></p><p id="p0045" class="elsevierStylePara elsevierViewall">The term “raccoon sign” should be limited to cases of periorbital ecchymosis, sparing the palpebral tarsus, due to fractures to the base of the skull. Bilateral palpebral haematomas caused by direct trauma to the orbital and facial region, or non-traumatic medical conditions, may extend beyond the tarsus. Differential diagnosis includes both trivial, benign conditions, and severe conditions, with neuroblastoma, multiple myeloma, and amyloidosis being the most frequent (<a class="elsevierStyleCrossRef" href="#t0005">Table 1</a>).</p><elsevierMultimedia ident="t0005"></elsevierMultimedia><p id="p0050" class="elsevierStylePara elsevierViewall">In conclusion, the raccoon sign is easy to identify in the physical examination. Its presence after head trauma is strongly associated with a fracture at the skull base. The presence of palpebral ecchymosis in the absence of a previous head trauma may serve as a warning sign for other possible diagnoses.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2022-12-08" "fechaAceptado" => "2023-04-01" "apendice" => array:1 [ 0 => array:1 [ "seccion" => array:1 [ 0 => array:4 [ "apendice" => "<p id="p0060" class="elsevierStylePara elsevierViewall"><elsevierMultimedia ident="ec0005"></elsevierMultimedia></p>" "etiqueta" => "Appendix A" "titulo" => "Supplementary data" "identificador" => "s0005" ] ] ] ] "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "f0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 620 "Ancho" => 827 "Tamanyo" => 113886 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Raccoon sign. Bilateral periorbital ecchymosis, sparing the palpebral tarsus, manifesting 2<span class="elsevierStyleHsp" style=""></span>days after head trauma.</p>" ] ] 1 => array:8 [ "identificador" => "t0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0010" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Trauma</span>Basilar skull fractureFacial or orbital trauma<a class="elsevierStyleCrossRef" href="#bb0020"><span class="elsevierStyleSup">4</span></a>Nasal or orbital surgery \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Autoimmune, inflammatory diseases</span>Sweet syndrome<a class="elsevierStyleCrossRef" href="#bb0025"><span class="elsevierStyleSup">5</span></a>Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE)Neonatal lupus erythematosusPigmented lichen planus \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Metabolic disorders</span>AmyloidosisMyxoedema \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Oncological diseases</span>Multiple myelomaMetastatic neuroblastomaOrbital metastasesKaposi sarcomaAcute myeloid leukaemiaLymphoblastic lymphoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Vascular diseases</span>Cerebral venous thrombosisTemporal arteritis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleBold">Others</span>Trigeminal autonomic cephalalgiaMigraineEndoscopic retrograde cholangiopancreatographyHaemophiliaFrontal sinus mucoceleSneezing, coughing, and vomiting \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3647217.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Causes of bilateral palpebral ecchymosis.</p>" ] ] 2 => array:7 [ "identificador" => "ec0005" "tipo" => "MULTIMEDIAECOMPONENTE" "mostrarFloat" => false "mostrarDisplay" => true "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0015" "detalle" => "Image " "rol" => "short" ] ] "Ecomponente" => array:2 [ "fichero" => "mmc1.pdf" "ficheroTamanyo" => 200629 ] "descripcion" => array:1 [ "en" => "<p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Supplementary material.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Raccoon eyes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.A. McPheeters" 1 => "S. White" 2 => "A. Winter" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "West J Emerg Med" "fecha" => "2010 Feb" "volumen" => "11" "numero" => "1" "paginaInicial" => "97" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20411091" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "'Raccoon eyes' (periorbital haematoma) as a sign of skull base fracture" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F.A. Herbella" 1 => "M. Mudo" 2 => "C. Delmonti" 3 => "F.M. Braga" 4 => "J.C. Del Grande" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/s0020-1383(01)00144-9" "Revista" => array:6 [ "tituloSerie" => "Injury." "fecha" => "2001 Dec" "volumen" => "32" "numero" => "10" "paginaInicial" => "745" "paginaFinal" => "747" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Positive predictive values of selected clinical signs associated with skull base fractures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Pretto Flores" 1 => "C.S. De Almeida" 2 => "L.A. Casulari" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Neurosurg Sci" "fecha" => "2000 Jun" "volumen" => "44" "numero" => "2" "paginaInicial" => "77" "paginaFinal" => "82" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11105835" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Teaching NeuroImages: unmasking raccoon eyes: a classic clinical sign" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Tarolli" 1 => "M.A. Scully" 2 => "A.D. Smith 3rd." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1212/WNL.0000000000000611" "Revista" => array:7 [ "tituloSerie" => "Neurology." "fecha" => "2014 Jul 22" "volumen" => "83" "numero" => "4" "paginaInicial" => "e58" "paginaFinal" => "e59" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25049310" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expanding the differential diagnosis of raccoon eyes: sweet syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Salman" 1 => "G. Demir" 2 => "L. Cinel" 3 => "T. Oguzsoy" 4 => "G. Yıldızhan" 5 => "T. Ergun" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jdv.15104" "Revista" => array:7 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2019 Jan" "volumen" => "33" "numero" => "1" "paginaInicial" => "e10" "paginaFinal" => "e12" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29852061" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/26670496/0000000400000003/v2_202409090816/S2667049624000085/v2_202409090816/en/main.assets" "Apartado" => array:4 [ "identificador" => "95389" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Editor Letter" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/26670496/0000000400000003/v2_202409090816/S2667049624000085/v2_202409090816/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2667049624000085?idApp=UINPBA00004N" ]
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