Article information
Resumen
Describimos el caso de una paciente femenina de 49 años con esclerosis sistémica difusa con compromiso cutáneo y pulmonar severo, rápidamente progresivo, sin respuesta al manejo inmunosupresor convencional; quien fue sometida a transplante de células madres hematopoyéticas (TCMH) con mejoría sostenida del compromiso cutáneo y pulmonar a los 6 meses post-TCMH.
Palabras clave:
transplante de células progenitoras hematopoyéticas
terapia inmunosupresora
enfermedades autoinmunes
esclerosis sistémica
Summary
The following case presents a 49 year-old patient with diffuse SSc and poor evolution given by rapidly progressive of severe skin and lung involvement, who had undergone autologous stem cell transplantation in December 2008. Sustained improvement of skin thickening and of major organ involvement was achieved at six months.
Key words:
autologous stem cell transplantation
immunosuppressive therapy
autoimmune diseases
systemic sclerosis
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