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Inicio Revista Española de Geriatría y Gerontología Clínica de la demencia con cuerpos de Lewy y evolución frente a la enfermedad ...
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Vol. 46. Issue S1.
Pages 19-23 (October 2011)
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Vol. 46. Issue S1.
Pages 19-23 (October 2011)
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Clínica de la demencia con cuerpos de Lewy y evolución frente a la enfermedad de Alzheimer
Symptoms of Lewy body dementia and clinical course compared with Alzheimer's disease
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Gregorio Jiménez
Servicio de Urgencias, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España
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Resumen

La demencia con cuerpos de Lewy (DCLw) es una enfermedad neurodegenerativa que presenta un cuadro clínico bien definido y con criterios clínicos establecidos, que se caracteriza por la presencia de demencia de características corticales y subcorticales, acompañada de algunos rasgos característicos como el parkinsonismo, la existencia de alucinaciones visuales y fluctuaciones en el nivel de alerta y atención, así como una hipersensibilidad frente a los neurolépticos. Si se compara con la enfermedad de Alzheimer, la DCLw parece presentar un curso clínico más rápido y con mayor mortalidad, en el que las diferencias respecto a ésta pueden resultar más evidentes en los estadios iniciales pero tienden a igualarse con el progreso de la enfermedad. La mayor presencia de síntomas neuropsiquiátricos y un mayor grado de dependencia en la DCLw conducen a una mayor sobrecarga del cuidador y, probablemente, condicionan un mayor consumo de recursos.

Palabras clave:
Demencia
Demencia con cuerpos de Lewy
Enfermedad de Alzheimer
Progresión
Curso clínico
Abstract

Lewy body dementia (LBD) is a neurodegenerative disease with well-defined symptoms and established clinical criteria, characterized by the presence of cortical and subcortical dementia, accompanied by some characteristic features such as Parkinsonism, visual hallucinations and fluctuations in alertness and attention, as well as hypersensitivity to neuroleptics. Compared with Alzheimer's disease, LBD seems to have a more rapid clinical course and greater mortality. The differences with Alzheimer's disease may be more apparent in the initial stages of the disease but tend to disappear with disease progression. Because of the greater presence of neuropsychiatric symptoms and the higher degree of dependency in LBD, there is greater caregiver overload and probably greater resource use.

Keywords:
Dementia
Lewy body dementia
Aizheimer's disease
Progression
Clinical course
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Copyright © 2011. SEGG
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