metricas
covid
Buscar en
Revista Española de Geriatría y Gerontología
Toda la web
Inicio Revista Española de Geriatría y Gerontología Morbimortalidad y factores asociados a abscesos hepáticos piógenos en paciente...
Journal Information
Vol. 37. Issue 3.
Pages 141-145 (January 2002)
Share
Share
Download PDF
More article options
Vol. 37. Issue 3.
Pages 141-145 (January 2002)
Full text access
Morbimortalidad y factores asociados a abscesos hepáticos piógenos en pacientes mayores de 60 años
Morbimortality and associated factors associated to pyogenic liver abscesses in patients over 60 years
Visits
4923
J.A. Álvarez Pérez
,
Corresponding author
josealvar@telecable.es

Correspondencia: Avenida de Galicia, 46-3° A. 33005 Oviedo.
, R.F. Baldonedo Cernuda*, J.J. González González**, I. García Bear*, L. Hernández Luyando***, F. García Arias****, P. Álvarez Martínez****, J.I. Jorge Barreiro****
* Servicio de Cirugía General. Hospital San Agustín. Avilés
** Servicio de Cirugía General B. Hospital Central Universitario. Universidad de Oviedo
*** Servicio de Radiología. Hospital Central Universitario. Universidad de Oviedo
**** Servicio de Radiología. Hospital San Agustín. Avilés
This item has received
Article information
Resumen
Introducción

El objetivo fue estudiar el curso evolutivo de los pacientes de edad avanzada con abscesos hepáticos piógenos, analizando la morbimortalidad y los factores asociados.

Pacientes y métodos

Se realizó un estudio retrospectivo y multicéntrico de 78 pacientes mayores de 60 años con abscesos hepáticos piógenos. La etiopatogenia biliar fue predominante (48,7%). La mayoría de los abscesos fueron únicos (66,7%) y de localización preferente en el lóbulo hepático derecho (65,5%). El tratamiento realizado fue antibioterapia en 14 casos (17,9%), drenaje percutáneo en 37 (47,4%) y drenaje quirúrgico en 27 (34,7%). La evolución clínica fue estudiada mediante el análisis de las complicaciones y de la mortalidad, además, se realizó un análisis bivariante para discriminar variables asociadas con la mortalidad.

Resultados

23 pacientes (29,5%) tuvieron complicaciones y 11 (14,1%) fallecieron por causas relacionadas con el absceso. Hubo complicaciones abdominales en 20 enfermos (25,6%), destacando la sepsis absceso-relacionada y la recidiva del absceso. Entre las complicaciones sistémicas, 21 casos (26,9%), sobresalieron las neumológicas. De las variables estudiadas, la existencia de distrés respiratorio (p= 0,03), un APACHE II alto (p= 0,04) y la presencia de gas en el absceso (p< 0,0001) se asociaron a mayor mortalidad.

Conclusiones

Los pacientes de edad avanzada con abscesos hepáticos piógenos sufren una elevada morbilidad y una nada despreciable mortalidad. La existencia de distrés respiratorio, gas en el absceso y signos de fallo orgánico se asociaron a la posibilidad de muerte.

Palabras clave:
Absceso hepático piógeno
Población anciana
Morbilidad
Mortalidad
Factores asociados
Summary
Introduction

It was aimed to study the outcome of older patients with pyogenic liver abscesses, analyzing the morbimortality and associated factors.

Material and methods

A retrospective and multicenter study of 78 patients over 60 years with pyogenic liver abscesses was performed. Biliary pathogenesis was predominant (48.7%). Most of the abscesses were solitary (66.7%) and mainly located in the right hepatic lobe (65.5%). Antibiotic treatment was performed in 14 cases (17.9%), percutaneous drainage in 37 (47.4%) and surgical drainage in 27 (34.7%). The clinical outcome was studied by the analysis of the complications and mortality. Moreover, an bivariate analysis was performed to identify the variables associated to mortality.

Results

A total of 23 patients (29.5%) developed complications and 11 (14.1%) died due to abscess-related causes. There were abdominal complications in 20 patients (25.6%), with emphasis on abscessrelated sepsis and recurrent abscess. Respiratory problems occurred more often among the 21 cases (26.9%) with systemic complications. Of the variables studied, the existence of respiratory distress (p= 0.03), a high APACHE II (p= 0.04) and the presence of gas in the abscess (p< 0.001) were associated with greater mortality.

Conclusion

High mortality and a relevant mortality were observed in older patients with pyogenic liver abscesses. The existence of respiratory distress, gas in the abscess and organic failure signs were associated with mortality.

Key words:
Pyogenic liver abscess
Elderly people
Morbidity
Mortality
Associated factors
Full text is only aviable in PDF
Bibliografía
[1.]
A. Ochsner, M. DeBakey, S. Murray.
Pyogenic abscess of the liver. An analysis of 47 cases with review of the literature.
Am J Surg, 40 (1938), pp. 292-319
[2.]
C.J. Huang, H.A. Pitt, P.A. Lipsett, F.A. Osterman, K.D. Lillemoe, J.L. Cameron, et al.
Pyogenic hepatic abscess. Changing trends over 42 years.
Ann Surg, 223 (1996), pp. 600-609
[3.]
J. Barrio, A. Cosme, E. Ojeda, G. Garmendia, A. Castiella, L. Bujanda, et al.
Abscesos hepáticos piógenos de origen bacteriano. Estudio de una serie de 45 casos.
Rev Esp Enf Digest, 92 (2000), pp. 232-235
[4.]
R. Rintoul, M.G. O’Riordain, I.F. Laurenson, J.L. Crosbie, P.L. Allan, O.J. Garden.
Changing management of pyogenic liver abscess.
Br J Surg, 83 (1996), pp. 1215-1218
[5.]
J.C. Corredoira Sánchez, E. Casariego Vales, M.D. Ibáñez Alonso, M.T. Rigueiro Veloso, A. Coira Nieto, P. Alonso García, et al.
Absceso hepático piógeno: cambios en la etiología, diagnóstico y tratamiento a lo largo de 18 años.
Rev Clin Esp, 199 (1999), pp. 705-710
[6.]
R.K. Seeto, D.C. Rockey.
Pyogenic liver abscess: Changes in etiology, management, and outcome.
Medicine, 75 (1996), pp. 99-113
[7.]
A.J. Greenstein, D. Lowenthal, G.S. Hammer, F. Schaffner, A.H. Aufses Jr..
Continuing changing patterns of disease in pyogenic liver abscess: A study of 38 patients.
Am J Gastroenterol, 79 (1984), pp. 217-226
[8.]
E.D. Bowers, D.J. Robison, R.C. Doberneck.
Pyogenic liver abscess.
World J Surg, 14 (1990), pp. 128-132
[9.]
K.T. Lee, P.C. Sheen, J.S. Chen, C.G. Ker.
Pyogenic liver abscess: Multivariate analysis of risk factors.
World J Surg, 15 (1991), pp. 372-377
[10.]
F.F. Chou, S.C. Shyr-Ming, Y.S. Chen, M.C. Chen, F.C. Chen, D.I. Tai.
Prognostic factors for pyogenic abscess of the liver.
J Am Coll Surg, 179 (1994), pp. 727-732
[11.]
K.M. Chu, S.T. Fan, E.C.S. Lai, C.M. Lo, J. Wong.
Pyogenic liver abscess: An audit of experience over the past decade.
Arch Surg, 131 (1996), pp. 148-152
[12.]
D.M. Beaumont, M. Davis.
Clinical presentation of pyogenic liver abscess in the elderly.
Age Ageing, 19 (1990), pp. 199-203
[13.]
G.V. Sridharan, S.P. Wilkinson, W.R. Primrose.
Pyogenic liver abscess in the elderly.
Age Ageing, 19 (1990), pp. 199-203
[14.]
W.A. Knaus, E.A. Draper, D.P. Wagner, J.E. Aimmerman.
APACHE II: a severity of disease classification.
Crit Care Med, 13 (1985), pp. 818-829
[15.]
S.H. Smoger, C.K. Mitchell, S.A. MaClave.
Pyogenic liver abscesses: a comparison of older and younger patients.
Age and Ageing, 27 (1998), pp. 443-448
[16.]
G.D. Branum, G.S. Tyson, M.A. Branum, W.C. Meyers.
Hepatic abscess. Changes in etiology, diagnosis, and management.
Ann Surg, 212 (1990), pp. 655-662
[17.]
B.W. Miedema, P. Dinnen.
The diagnosis and treatment of pyogenic liver abscesses.
Ann Surg, 200 (1984), pp. 328-334
[18.]
E.J. Gyorffy, C.F. Frey, J. Silva Jr., J. McGahan.
Pyogenic liver abscess. Diagnostic and therapeutic strategies.
Ann Surg, 206 (1987), pp. 699-705
[19.]
E. Jiménez, G. Tiberio, J. Sánchez, F.J. Jiménez, G. Jiménez.
Abscesos hepáticos piógenos: experiencia de 16 años en su diagnóstico y tratamiento.
Enfer Infecc Microbiol Clin, 16 (1998), pp. 307-311
[20.]
R. Cuberes, R. Garrido, A. Suárez, A. Torres, F. Hernández, S. de la Torre, et al.
Abscesos hepáticos piógenos no hidatídicos.
Cir Esp, 48 (1990), pp. 175-179
[21.]
F.F. Chou, S.M. Sheen-Chen, Y.S. Chen, M.C. Chen.
Single and multiple pyogenic liver abscesses: Clinical course, etiology, and results of treatment.
World J Surg, 21 (1997), pp. 384-389
[22.]
R.E. Lambiase, L. Deyoe, J.J. Cronan, G.S. Dorfman.
Percutaneous drainage of 335 consecutive abscesses: results of primary drainage with 1-year follow-up.
Radiology, 184 (1992), pp. 167-179
[23.]
R. Almenara, M. Barjadí, E. Cugat, E. García-Olivares, J. Centeno, M. García, et al.
Absceso hepático piógeno. Opciones terapéuticas.
Cir Esp, 53 (1983), pp. 251-255
[24.]
C.K. Bertel, J.A. van Heerden, P.F. Sheedy II.
Treatment of pyogenic hepatic abscesses Surgical vs. percutaneous drainage.
Arch Surg, 121 (1986), pp. 554-558
[25.]
M. Balasegaram.
Management of hepatic abscess.
Curr Probl Surg, 18 (1981), pp. 282-340
[26.]
B. Klatchko, S.I. Schwartz.
Diagnostic and therapeutic approaches to pyogenic abscess of the liver.
Surg Gynecol Obstet, 168 (1989), pp. 332-336
[27.]
R.B. Dietrick.
Experience with liver abscess.
Am J Surg, 147 (1984), pp. 288-291
[28.]
S.C. Stain, A.E. Yellin, A.J. Donovan, H.W. Brien.
Pyogenic liver abscess. Modern treatment.
Arch Surg, 126 (1991), pp. 991-996
[29.]
C.L. Rajak, S. Gupta, S. Jain, Y. Chawla, M. Gulati, S. Suri.
Percutaneous treatment of liver abscesses: needle aspiration versus catheter drainage.
Am J Roentgenol, 170 (1998), pp. 1035-1039
[30.]
H.A. Pitt.
Surgical management of hepatic abscesses.
World J Surg, 14 (1990), pp. 498-504
[31.]
A.J. Donovan, A.E. Yellin, P. Ralls.
Hepatic abscess.
World J Surg, 15 (1991), pp. 162-169
[32.]
J.A. Álvarez, J.J. González, R.F. Baldonedo, L. Sanz, G. Carreño, A. Junco, et al.
Clinical course, treatment, and multivariate analysis of risk factors for pyogenic liver abscess.
Am J Surg, 181 (2000), pp. 177-186
[33.]
H.J. Mischinger, H. Hauser, H. Rabl, F. Quehenberger, G. Werkgartner, R. Rubin, et al.
Pyogenic liver abscess: Studies of therapy and analysis of risk factors.
World J Surg, 18 (1994), pp. 852-858
[34.]
H.A. Pitt, G.D. Zuidema.
Factors influencing mortality in the treatment of pyogenic hepatic abscess.
Surg Gynecol Obstet, 140 (1975), pp. 228-234
[35.]
R.H. Rubin, M.N. Swartz, R. Malt.
Hepatic abscess: changes in clinical, bacteriologic and therapeutic aspects.
Am J Med, 57 (1974), pp. 601-610
[36.]
C.C. Yang, C.Y. Chen, X.Z. Lin, T.T. Chang, J.S. Shin, C.Y. Lin.
Pyogenic liver abscess in Taiwan: Emphasis on gas-forming liver abscess in diabetics.
Am J Gastroenterol, 88 (1993), pp. 1911-1915
[37.]
T.Y. Lee, Y.L. Wan, C.C. Tsai.
Gas-forming liver abscess: radiological findings and clinical significance.
Abdom Imaging, 19 (1994), pp. 47-52
[38.]
F.F. Chou, S.M. Sheen-Chen, Y.S. Chen, T.Y. Lee.
The comparison of clinical course and results of treatment between gas-forming and non-gas-forming pyogenic liver abscess.
Arch Surg, 130 (1995), pp. 401-405
[39.]
J.A. Álvarez, J.J. González, R.F. Baldonedo, L. Sanz, G. Carreño, J.I. Jorge.
Single and multiple pyogenic liver abscesses: Etiology, clinical course, and outcome.
Dig Surg, 18 (2001), pp. 283-288
Copyright © 2002. Sociedad Española de Geriatría y Gerontología
Download PDF
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos