metricas
covid
Buscar en
Revista Española de Patología
Toda la web
Inicio Revista Española de Patología Complete spontaneous regression of a primary renal cell carcinoma. Report of a p...
Journal Information
Vol. 55. Issue S1.
Artículos breves de especial interés
Pages S69-S73 (September 2022)
Share
Share
Download PDF
More article options
Visits
22
Vol. 55. Issue S1.
Artículos breves de especial interés
Pages S69-S73 (September 2022)
Original
Complete spontaneous regression of a primary renal cell carcinoma. Report of a pathological proven case and review of the literature
Regresión espontánea completa de un carcinoma renal primario. Descripción de un caso con comprobación histológica y revisión de la literatura
Visits
22
Alwalid Freih-Fraiha, Guillermo Celada-Luisb, Tamara Ranchala, Claudio Laganac, Alberto Canca-Velascob, José A. Jiménez-Heffernana,
Corresponding author
jjheffernan@yahoo.com

Corresponding author.
a Department of Pathology, University Hospital La Princesa, Madrid, Spain
b Department of Urology, University Hospital La Princesa, Madrid, Spain
c Department of Radiology, University Hospital La Princesa, Madrid, Spain
This item has received
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Special issue
This article is part of special issue:
Vol. 55. Issue S1

Artículos breves de especial interés

More info
Abstract

Regression of primary renal cell carcinoma (RCC) is a rare phenomenon and for several reasons many of the reported cases have been questioned. We present a case that can be considered a true spontaneous and complete regression of a primary RCC. A 79-year-old female underwent nephrectomy because a renal tumor. At the time of surgery image studies showed a small para-aortic lymph node. The tumor measured 3cm and was analyzed completely. Histology showed a fibro-inflammatory lesion with necrosis, foamy macrophages and inflammatory cells. No neoplastic cells were observed and the lesion was interpreted as a localized type of xanthogranulomatous pyelonephritis. One year later a CT control scan, showed that the para-aortic lymph node had increased in size to 4cm. Fine needle aspiration revealed features of clear RCC. Metastatic dissemination was limited so surgical removal of the para-aortic lymph node was performed and the cytologic diagnosis confirmed.

Keywords:
Renal cell carcinoma
Spontaneous tumoral regression
Tumoral necrosis
Resumen

La regresión espontanea del carcinoma primario de células renales (CCR) es un hecho infrecuente y, por diferentes motivos, los casos descritos han sido cuestionados. Presentamos un caso que creemos cumple con los criterios para ser considerado como una regresión completa de un CCR. Una mujer de 79 años fue sometida a una nefrectomía por un tumor renal. En ese momento los estudios de imagen mostraron un pequeño ganglio paraaórtico. El tumor de 3cm se analizó completamente. La histología mostró una lesión fibroinflamatoria con necrosis, macrófagos xantomizados y células inflamatorias. No se observaron células neoplásicas y la lesión se interpretó como una pielonefritis xantogranulomatosa localizada. Un año después, una TAC de control mostró crecimiento del ganglio paraaórtico (4cm). Se realizó punción con aguja fina que mostró características propias de un CCR. Dado que la diseminación metastásica era limitada, se extirpó el ganglio linfático confirmándose el diagnóstico citológico.

Palabras clave:
Carcinoma renal
Regresión tumoral espontánea
Necrosis tumoral

Article

These are the options to access the full texts of the publication Revista Española de Patología
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Revista Española de Patología

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos