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Vol. 39. Issue 1.
Pages 54-58 (January - March 2006)
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Vol. 39. Issue 1.
Pages 54-58 (January - March 2006)
Casuística
CD10 y mesotelioma maligno. A propósito de un caso
CD10 and malignant mesothelioma. Report of a case
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Francesc Alameda Quitllet1, Irene Moysset Agustí2, Josep Lloreta Trull1, Teresa Baró Tomás1, Luis Magán Perea1, Josep Badal Alter2, Sergi Serrano Figueras1
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Resumen

Aportamos un caso de mesotelioma maligno en una mujer de 37 años con antecedentes de laparoscopia por leiomiomas uterinos. El diagnostico de mesotelioma se estableció por autopsia. El estudio inmunohistoquímico del tumor mesotelial, reveló intensa positividad para CD10, y ausencia de inmunoreactividad para receptores de estrógenos y de progesterona y calretinina. En nuestra serie de mesoteliomas observamos que alrededor del 30% de ellos expresaban CD10. En la revisión de la Literatura se observó que aproximadamente el 40% de los mesoteliomas, mostraban inmunoreactividad para CD10. En conslusión nuestras observaciones muestran que CD10 puede expresarse de forma extensa en los mesoteliomas, dato que puede ayudar al establecer un diagnóstico diferencial en estos casos.

Palabras clave:
Mesotelioma: CD10
Summary

We report a case of malignant mesothelioma in a 37 year-old woman treated for uterine leiomyomas. The diagnosis of mesothelioma was stablished based on autopsy study. The immunohistochemical study of mesothelial tumor showed strong CD10 immunoreactivity. Our series of mesotheliomas was also retrospectively studied with anti-CD10 and around 30% of them expressed CD10. Around 40% of mestohelioma cases reported in the Literature express CD10. We conclude that CD10 could be expressed in some mesothelial tumors, and may help to stablish a differential diagnosis in some cases.

Key words:
Mesothelioma
CD10

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