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Inicio Revista Española de Patología Correlación entre la densidad vascular y la expresión inmunohistoquímica de f...
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Vol. 39. Issue 3.
Pages 167-170 (July - September 2006)
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Vol. 39. Issue 3.
Pages 167-170 (July - September 2006)
Originales
Correlación entre la densidad vascular y la expresión inmunohistoquímica de factores pronósticos en el carcinoma ductal infiltrante de mama
Correlationship between vascular density and immunohistochemical expression on prognostic factors in invasive ductal carcinoma of the breast
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Francisco Javier Torres Gómez1, Francisco Javier Torres Olivera2
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Resumen
Introducción

El carcinoma ductal infiltrante es un tumor dependiente de la angiogénesis para aumentar su tamaño y metastatizar. Hemos establecido la correlación entre la densidad vascular tumoral y los factores pronósticos con expresión inmunohistoquímica.

Material y métodos

Se ha determinado la densidad vascular tumoral sobre el mejor punto caliente en un campo microscópico a 400x y se ha determinado inmunohistoquímicamente la expresión de receptores estrogénicos, p53 y c-erb2 en cada una de las 165 pacientes con carcinoma ductal infiltrante (NOS).

Resultados

No hemos obtenido correlación significativa entre la expresión de receptores estrogénicos, p53 y c-erb2 y la densidad vascular en el carcinoma ductal infiltrante de mama.

Palabras clave:
Carcinoma ductal infiltrante
angiogénesis
receptores estrogénicos
p53
c-erb2
Summary
Introduction

Invasive ductal carcinoma of the breast is an angiogenesis dependent tumour in order to growth and metastatize. We have correlate tumoral vascular density and the different prognostic factors with immunohistochemical expression.

Material and methods

We have calculated the tumoral vascular density in the best hot spot using a 400 x microscopic field and settling immunohistochemically the estrogen receptors, p53 and c-erb2 expression in each of the 165 patients with invasive ductal carcinoma.

Results

We have not demonstrated significant correlation between estrogen receptor, p53 and c-erb2 expression and the vascular density in the invasive ductal carcinoma of the breast.

Keywords:
Invasive ductal carcinoma
angiogenesis
estrogen receptors
p53 and c-erb2

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