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Vol. 39. Issue 3.
Pages 135-148 (July - September 2006)
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Vol. 39. Issue 3.
Pages 135-148 (July - September 2006)
Revisiones
Liposarcomas. Aspectos clínico-patológicos y moleculares
Liposarcomas. Clinicopathological and molecular aspects
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Juan Segura Sánchez1, María Jesús Pareja Megía2, Antonio García Escudero2, María Teresa Vargas De Los Monteros2, Ricardo González-Cámpora2
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Resumen

Los liposarcomas constituyen el grupo más numeroso de sarcomas del adulto. Su interés actual radica fundamentalmente en los cambios conceptuales y clasificatorios que han acontecido en los últimos años merced a la aplicación de las técnicas de citogenética y de biología molecular. En la presente revisión se lleva a cabo una correlación clínico patológica de los cinco tipos básicos de liposarcomas y se comentan los aspectos citogenéticos y de biología molecular que han permitido la elaboración de la nueva clasificación de la OMS.

Palabras clave:
Liposarcomas
citogenética
biología molecular
Summary

Liposarcomas are the most common sarcoma of the adult life. Their current interest is based on the recent molecular and cytogenetic changes that have allowed the new WHO classification. In the present report we carried out a clinicopathological correlation in the five distinctive groups of the current classification and described the most relevant cytogenetics and molecular findings in each group.

Key words:
Liposarcoma
cytogenetics
molecular biology

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