Journal Information
Vol. 3. Issue 4.
Pages 115-118 (January 2010)
Vol. 3. Issue 4.
Pages 115-118 (January 2010)
Full text access
A paradigm shift in modern psychiatric diagnosis? Neural network dysfunction as a pathophysiological concept and novel diagnostic tool
¿Un cambio de paradigma en el diagnóstico psiquiátrico moderno? Anomalías en las redes neuronales como concepto fisiopatológico y nueva herramienta de diagnóstico
Visits
1002
David Prvulovic, Harald Hampel
Corresponding author
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy Goethe-University of Frankfurt, Germany
This item has received
Article information
Full text is only aviable in PDF
References
[1.]
H. Jaaro-Peled, Y. Ayhan, M.V. Pletnikov, A. Sawa.
Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models.
Schizophr Bull, 36 (2010), pp. 301-313
[2.]
P. Vemuri, H.J. Wiste, S.D. Weigand, L.M. Shaw, J.Q. Trojanowski, M.W. Weiner, D.S. Knopman, R.C. Petersen, C.R. Jack Jr.
Alzheimer's Disease Neuroimaging Initiative. MRI and CSF biomarkers in normal MCI, and AD subjects: diagnostic discrimination and cognitive correlations.
Neurology, 73 (2009), pp. 287-293
[3.]
T. Dierks, D.E. Linden, A. Hertel, T. Günther, H. Lanfermann, A. Niesen, L. Frölich, F.E. Zanella, G. Hör, R. Goebel, K. Maurer.
Multimodal imaging of residual function and compensatory resource allocation in cortical atrophy: a case study of parietal lobe function in a patient with Huntington's disease.
Psychiatry Res, 90 (1999), pp. 67-75
[4.]
S.Y. Bookheimer, M.H. Strojwas, M.S. Cohen, A.M. Saunders, M.A. Pericak- Vance, J.C. Mazziotta, G.W. Small.
Patterns of brain activation in people at risk for Alzheimer's disease.
N Engl J Med, 343 (2000), pp. 450-456
[5.]
D. Prvulovic, V. Van de Ven, A.T. Sack, K. Maurer, D.E. Linden.
Functional activation imaging in aging and dementia.
Psychiatry Res, 140 (2005), pp. 97-113
[6.]
E. Bullmore, O. Sporns.
Complex brain networks: graph theoretical analysis of structural and functional systems.
Nat Rev Neurosci, 10 (2009), pp. 186-198
[7.]
A.L. Bokde, P. Lopez-Bayo, T. Meindl, S. Pechler, C. Born, F. Faltraco, S.J. Teipel, H.J. Möller, H. Hampel.
Functional connectivity of the fusiform gyrus during a face-matching task in subjects with mild cognitive impairment.
Brain, 129 (2006), pp. 1113-1124
[8.]
A.L. Bokde, M. Ewers, H. Hampel.
Assessing neuronal networks: understanding Alzheimer's disease.
Prog Neurobiol, 89 (2009), pp. 125-133
[9.]
T. Hedden, K.R. Van Dijk, J.A. Becker, A. Mehta, R.A. Sperling, K.A. Johnson, R.L. Buckner.
Disruption of functional connectivity in clinically normal older adults harboring amyloid burden.
J Neurosci, 29 (2009), pp. 12686-12694
[10.]
C. Sorg, V. Riedl, M. Mühlau, V.D. Calhoun, T. Eichele, L. Läer, A. Drzezga, H. Förstl, A. Kurz, C. Zimmer, A.M. Wohlschläger.
Selective changes of resting-state networks in individuals at risk for Alzheimer‘s disease.
Proc Natl Acad Sci U S A., 104 (2007), pp. 18760-18765
[11.]
N. Filippini, B.J. MacIntosh, M.G. Hough, G.M. Goodwin, G.B. Frisoni, S.M. Smith, P.M. Matthews, C.F. Beckmann, C.E. Mackay.
Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele.
Proc Natl Acad Sci U S A., 106 (2009), pp. 7209-7214
[12.]
J.J. Palop, L. Mucke.
Synaptic depression and aberrant excitatory network activity in Alzheimer‘s disease: two faces of the same coin?.
Neuromolecular Med, 12 (2010), pp. 48-55
[13.]
P.J. Uhlhaas, W. Singer.
Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology.
Neuron, 52 (2006), pp. 155-168
[14.]
Y.I. Sheline, J.L. Price, Z. Yan, M.A. Mintun.
Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus.
Proc Natl Acad Sci U S A., 107 (2010), pp. 11020-11025
[15.]
H. Hampel, R. Frank, K. Broich, S.J. Teipel, R.G. Katz, J. Hardy, K. Herholz, A.L. Bokde, F. Jessen, Y.C. Hoessler, W.R. Sanhai, H. Zetterberg, J. Woodcock, K. Blennow.
Biomarkers for Alzheimer‘s disease: academic, industry and regulatory perspectives.
Nat Rev Drug Discov, 9 (2010), pp. 560-574
[17.]
M.D. Fox, M. Greicius.
Clinical applications of resting state functional connectivity.
Front Syst Neurosci, 17 (2010), pp. 4-19
[18.]
Hampel H, Wilcock G, Andrieu S, Aisen P, Blennow K, Broich K, Carrillo M, Fox N, Frisoni G, Isaac M, Lovestone S, Nordberg A, Prvulovic D, Sampaio C, Scheltens P, Weiner M, Winblad B, Coley N, Vellas B. Biomarkers for Alzheimer's Disease Therapeutic Trials Progress in Neurobiology . In press.
Copyright © 2010. SEP y SEPB