Sphenoid sinusitis with intracranial extension produced by an emergent fungus

Abstract

This is a case of fungal sphenoid sinusitis in a diabetic patient with non-specific symptoms and bone erosion radiological findings in the superior and posterior sphenoid walls. Surgical treatment was performed by transnasal endoscopic approach and voriconazole orally thereafter.

The histopathological study found fungus hyphal without mucosa invasion and the molecular study determined DNA to be Phialemonium curvatum, an unusual pathogen.

Resumen

Sinusitis fúngica esfenoidal en paciente diabética, con clínica inespecífica y signos de erosión ósea radiológica a nivel sellar superior y retroclival. Tratada quirúrgicamente por abordaje endoscópico transnasal y voriconazol oral. La histología mostró hifas, descartando invasión mucosa y el estudio molecular detectó ADN de Phialemonium curvatum, un inusual patógeno.