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Inicio Actas Urológicas Españolas (English Edition) Entering into 2.0 cystinuric management with a medical digital tool to monitor u...
Journal Information
Vol. 47. Issue 9.
Pages 560-565 (November 2023)
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Vol. 47. Issue 9.
Pages 560-565 (November 2023)
Original article
Entering into 2.0 cystinuric management with a medical digital tool to monitor urine pH: a prospective, randomized study
Entrando en el manejo 2.0 de la cistinuria con una herramienta médica digital para monitorizar el pH de la orina: un estudio prospectivo y aleatorizado
O. Angerria,
Corresponding author
33802oaf@comb.cat

Corresponding author.
, S. Graciab, F. Rousauda, A. Kanashiroa, E. Emiliania
a Department of Urology, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain
b Department of Laboratory and Biochemistry, Fundació Puigvert, Universitat Autònoma de Barcelona, Spain
Article information
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Figures (1)
Tables (2)
Table 1. Participants’ and urine characteristics.
Table 2. Urine pH recorded by each method during the three intervals of the study.
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Abstract
Background and objectives

Individuals with cystinuria can experiment recurrent lithiasis events due to the relative insolubility of cystine at physiological urine pH, resulting in renal function decline. The Lit-Control® pH Meter is a medical device that accurately allows urine pH self-monitoring. The main objective of this study was to compare the usability of the Lit-Control® pH Meter with the reactive strips for self-monitoring of urinary pH at home by patients with cystinuria, and their overall satisfaction with each tool.

Patients and methods

We included 28 patients (9 females and 19 males, age 19–76 years), who were randomly assigned to monitor their urine pH with reactive strips (n = 17) or the Lit-Control® pH-meter (n = 11).

Results

After six months of use, the satisfaction with the two methods was similarly high, but the patients rated (0–10 scale) the pH meter better in terms of ease of learning (mean ± SD, 8.11 ± 0.60 vs. 7.06 ± 1.18; P = 0.038), ease to prepare (8.22 ± 0.67 vs. 7.25 ± 1.18; P = 0.034), and ease of use (8.22 ± 0.67 vs. 7.25 ± 1.39; P = 0.062). Overall, patients did not reach the alkalinization goals (pH between 7.0 and 8.0).

Conclusions

The Lit-Control® pH Meter demonstrated to be an easy-to-use device that can facilitate urinary pH control by cystinuric patients. A prospective study is warranted to assess the correlation between urine pH monitoring, a treat to target approach, and the recurrence of cystine stones.

Keywords:
Cystinuria
Urolithiasis
Urine pH
Digital health
pH-meter
Usability
Resumen
Introducción y objetivos

Las personas con cistinuria pueden experimentar eventos recurrentes de litiasis debido a la relativa insolubilidad de la cistina en el pH fisiológico de la orina, lo que resulta en deterioro de la función renal. El pHmetro Lit-Control® es un dispositivo médico que permite la automedición predisa del pH de la orina. El objetivo principal de este estudio fue comparar la usabilidad del pHmetro LitControl® con las tiras reactivas para la auto-monitorización domiciliaria del pH urinario por parte de pacientes con cistinuria, y su satisfacción general con cada herramienta.

Pacientes y métodos

Se incluyeron 28 pacientes (9 mujeres y 19 hombres, de 19 a 76 anos), que fueron asignados aleatoriamente a monitorizar su pH urinario con tiras reactivas (n = 17) o el pH-metro Lit-Control® (n = 11).

Resultados

Después de seis meses de uso, la satisfacción con los dos métodos fue similarmente alta, pero los pacientes calificaron (en una escala de 0 a 10) mejor el pHmetro en términos de facilidad de aprendizaje (media ± DE, 8,11 ± 0,60 vs. 7,06 ± 1,18; P = 0,038), facilidad de preparación (8,22 ± 0,67 vs. 7,25 ± 1,18; P = 0,034) y facilidad de uso (8,22 ± 0,67 vs. 7,25 ± 1,39; P = 0,062). En general, los pacientes no alcanzaron los objetivos de alcalinización (pH entre 7,0 y 8,0).

Conclusiones

El pHmetro Lit-Control® demostró ser un dispositivo fácil de usar que puede facilitar el control del pH urinario en pacientes con cistinuria. Queda justificado un estudio prospectivo para evaluar la correlación entre la monitorización del pH de la orina, una estrategia.

Palabras clave:
Cistinuria
Urolitiasis
pH urinario
Salud digital
pHmetro
Usabilidad

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