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array:23 [ "pii" => "S0210480608739755" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73975-5" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73975" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:976-84" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1188 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 703 "PDF" => 480 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480608739767" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73976-7" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73976" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:985-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1211 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 824 "PDF" => 380 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Ablación por radiofrecuencia de lesiones renales: experiencia inicial en un centro de referencia en la ciudad de México (INNSZ)" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "985" "paginaFinal" => "988" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Radiofrequency ablation of renal lesions: initial experience in a center of reference in mexico city (innsz)" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L.G. Vázquez-Lavista, C.H. Flores-Balcazar, C.E. Méndez-Probst, B. Gabilondo-Pliego, M. Sotomayor-de-Zavaleta, G. Feria-Bernal, T. Cabrera-Aleksandrova" "autores" => array:7 [ 0 => array:2 [ "nombre" => "L.G." "apellidos" => "Vázquez-Lavista" ] 1 => array:2 [ "nombre" => "C.H." "apellidos" => "Flores-Balcazar" ] 2 => array:2 [ "nombre" => "C.E." "apellidos" => "Méndez-Probst" ] 3 => array:2 [ "nombre" => "B." "apellidos" => "Gabilondo-Pliego" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Sotomayor-de-Zavaleta" ] 5 => array:2 [ "nombre" => "G." "apellidos" => "Feria-Bernal" ] 6 => array:2 [ "nombre" => "T." "apellidos" => "Cabrera-Aleksandrova" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608739767?idApp=UINPBA00004N" "url" => "/02104806/0000003200000010/v1_201304251917/S0210480608739767/v1_201304251917/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480608739743" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73974-3" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73974" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:968-75" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1287 "formatos" => array:3 [ "EPUB" => 8 "HTML" => 830 "PDF" => 449 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Prostatectomía radical: comparación de los resultados obtenidos durante las curvas de aprendizaje de la técnica laparoscópica pura y de la técnica asistida por robot con la prostatectomía radical retropúbica" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "968" "paginaFinal" => "975" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Radical prostatectomy: evaluation of learning curve outcomes laparoscopic and robotic-assisted laparoscopic techniques with radical retropubic prostatectomy" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.P. Caballero Romeu, J. Palacios Ramos, J.G. Pereira Arias, M. Gamarra Quintanilla, A. Astobieta Odriozola, G. Ibarluzea González" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.P." "apellidos" => "Caballero Romeu" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Palacios Ramos" ] 2 => array:2 [ "nombre" => "J.G." "apellidos" => "Pereira Arias" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Gamarra Quintanilla" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Astobieta Odriozola" ] 5 => array:2 [ "nombre" => "G." "apellidos" => "Ibarluzea González" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608739743?idApp=UINPBA00004N" "url" => "/02104806/0000003200000010/v1_201304251917/S0210480608739743/v1_201304251917/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Características clínico-patológicas del carcinoma de células renales detectado incidentalmente mediante estudios radiológicos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "976" "paginaFinal" => "984" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "V. Bulnes Vázquez, M. Álvarez-Múgica, J.M. Fernández Gómez, E. Nava Tomás, A. Jalón Monzón, Á. Meilán Martínez" "autores" => array:6 [ 0 => array:4 [ "nombre" => "V." "apellidos" => "Bulnes Vázquez" "email" => array:1 [ 0 => "vebulnesv@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Álvarez-Múgica" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J.M." "apellidos" => "Fernández Gómez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "E." "apellidos" => "Nava Tomás" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "A." "apellidos" => "Jalón Monzón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "Á." "apellidos" => "Meilán Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Radiodiagnóstico 1. Hospital Universitario Central de Asturias." "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Urología 1. Hospital Universitario Central de Asturias." "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dra. V. Bulnes Vázquez Servicio de Urología 1. Hospital Universitario Central de Asturias Celestino Villamil, s/n - 33006 Oviedo (Asturias) Tel.: 985 108 004" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Clinicopathologic features of renal cell carcinoma incidentally detected through radiological studies" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-01-01" "fechaAceptado" => "2008-06-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec88740" "palabras" => array:3 [ 0 => "Carcinoma de células renales" 1 => "Ecografía" 2 => "Escáner" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec88739" "palabras" => array:3 [ 0 => "Renal cell carcinoma" 1 => "Ultrasound" 2 => "CT Scan" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar el motivo de diagnóstico del carcinoma renal y su variación a lo largo de los años en los Servicios de Radiodiagnóstico 1 y Urología 1 del Hospital Universitario Central de Asturias (HUCA), comparando los periodos 1970-1995 y 1996-2005 y determinar si el hallazgo incidental puede explicar de forma independiente el pronóstico de estos tumores o es dependiente de sus características clínico-patológicas.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se llevó a cabo una revisión exhaustiva de las historias clínicas, de manera retrospectiva, de 373 carcinomas de células renales sometidos a resección quirúrgica entre los años 1970 y 2005, recogiéndose unos datos según un protocolo establecido.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De los 373 tumores de nuestra serie, 146 (39,1%) fueron diagnosticados según nuestros criterios de forma incidental, mientras que 227 (60,9%) lo fueron por presentar clínica sospechosa de presencia de un tumor. Cuando realizamos el recuento distribuyendo estos pacientes en dos grupos, por un lado los diagnosticados entre los años 1970-1995, y por otro lado los diagnosticados entre 1996-2005, observamos un incremento significativo en el número de tumores diagnosticados de forma incidental en el segundo periodo. Encontramos como factores independientes en la supervivencia cáncer específica la presencia de metástasis, la invasión microvascular de la pieza quirúrgica y el tratamiento de la recidiva (quirúrgico vs otros), mientras que los factores independientes de la recidiva resultaron ser el grado nuclear, la presencia de adenopatías y el estadio T3, por tanto la presencia de clínica no fue un factor independiente de recidiva ni de supervivencia cáncer específico.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Clásicamente el carcinoma de células renales se diagnosticaba cuando presentaba síntomas locales (la hematuria y el dolor lumbar, eran los más frecuentes), síntomas derivados de las metástasis o por la expresión de un síndrome paraneoplásico. Desde la generalización de la ecografía y la tomografía computerizada (TC) en el estudio de la patología abdominal ha aumentado de forma espectacular el descubrimiento de adenocarcinomas renales asintomáticos. Cabe destacar, en nuestro estudio, que a pesar de que los pacientes diagnosticados con tumores incidentales presentaron un mayor tiempo libre de enfermedad y de supervivencia sin embargo, la presencia de clínica no fue un factor independiente ni de recidiva ni de supervivencia cáncer específico.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To evaluate the reason for diagnosis of renal cell carcinoma and its variation over the years in Radiology 1 and Urology 1 departments of the Asturias Central Universitary Hospital (HUCA) comparing periods 1970-1995 and 1996-2005 and determine whether incidental findings may explain in an independent the prognosis of these tumors or it is dependent on its clinicopathologic characteristics.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conducted retrospectively, an exhaustive review of medical records of 373 renal cell carcinoma patients that underwent surgical resection during the period 1970-2005, collecting data according to a set protocol.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of the 373 tumors in our series, 146 (39,1%) were diagnosed according to our criteria incidentally, while 227 (60,9%) were diagnosed due to clinical suspicion of a tumor presence. We observed a significant increase in the number of tumors incidentally diagnosed in the second period, when we performed the counting distributing these patients into two groups, firstly those diagnosed between the years 1970-1995 and, secondly, those diagnosed between 1996-2005. We found metastasis, microvascular invasion of surgical piece and treatment of the recurrence as independent factors for specific cancer survival, while nuclear grade, the presence of lymphadenopathies and T3 stage were found as independent factors for recurrence.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Classically renal cell carcinoma was diagnosed when local symptoms were present (hematuria and back pain, were the most common), symptoms associated with metastasis, or the expression of a paraneoplastic syndrome. The discovery of asymptomatic renal cell carcinomas has dramatically increased, since the widespread use of ultrasound and computed tomography (CT) in the study of abdominal pathology. It is worth mentioning that, in our study, although patients diagnosed with incidental tumors had a longer time free to recurrence and survival, however, the presence of clinic was not an independent risk factor for recurrence or cancer-specific survival.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:18 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Martin Jerry L. Cancer Epidemiology. In Super course Lectures. En: http://www.pitt.edu/super1/lectura/lec0192/001.htm.">http://www.pitt.edu/super1/lectura/lec0192/001.htm." ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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