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"apellidos" => "Santiago Gonzalez de Garibay" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608739809?idApp=UINPBA00004N" "url" => "/02104806/0000003200000010/v1_201304251917/S0210480608739809/v1_201304251917/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480608739780" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73978-0" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73978" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:995-1003" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1096 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 731 "PDF" => 358 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Factores determinantes de la satisfacción del paciente con el tratamiento para la disfunción eréctil" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "995" "paginaFinal" => "1003" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Determining factors in patient satisfaction with erectile dysfunction treatment" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.A. Delgado Martín, J. Blázquez Izquierdo, A. Silmi Moyano, E. Martínez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J.A." "apellidos" => "Delgado Martín" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Blázquez Izquierdo" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Silmi Moyano" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Martínez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608739780?idApp=UINPBA00004N" "url" => "/02104806/0000003200000010/v1_201304251917/S0210480608739780/v1_201304251917/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Influencia de la impronta genómica masculina en la reproducción" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "1004" "paginaFinal" => "1012" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "G.C. Vasco, A.M. Gil Villa, C. Piedrahita Ochoa, W. Cardona Maya, A. Cadavid Jaramillo" "autores" => array:5 [ 0 => array:4 [ "nombre" => "G.C." "apellidos" => "Vasco" "email" => array:2 [ 0 => "cadavida@une.net.co" 1 => "reproduccion@medicina.udea.edu.co" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A.M." "apellidos" => "Gil Villa" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Piedrahita Ochoa" ] 3 => array:2 [ "nombre" => "W." "apellidos" => "Cardona Maya" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Cadavid Jaramillo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Grupo Reproducción. Sede de Investigación Universitaria (SIU). Universidad de Antioquia. Medellín, Colombia" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dra. A. Cadavid Jaramillo Grupo Reproducción Sede de Investigación Universitaria (SIU) Universidad de Antioquia Medellín, Colombia, Sur América, A.A.1226. Tel: (57-4)-2196685 Fax: (57-4)-2196470" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Influence of the Male Genomic Imprinting on the Reproduction" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-01-05" "fechaAceptado" => "2008-07-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88744" "palabras" => array:5 [ 0 => "Espermatozoide" 1 => "Impronta" 2 => "Fertilidad" 3 => "Desarrollo embrionario" 4 => "Placenta" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88743" "palabras" => array:5 [ 0 => "Spermatozoa" 1 => "Genomic imprinting" 2 => "Fertility" 3 => "Embryo development" 4 => "Placenta" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La impronta genómica es la modificación epigenética que ocurre de manera diferencial tanto en genes específicos del oocito como del espermatozoide de acuerdo con su origen paterno o materno, permitiendo así una expresión monoalélica. En esta revisión se realiza un análisis crítico de la información relacionada con el papel que tiene la impronta masculina sobre el éxito reproductivo.</p> <span class="elsevierStyleSectionTitle">Metodología</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se hizo una búsqueda bibliográfica sobre algunos de los componentes que regulan la impronta geonómica masculina y el posible papel sobre los eventos reproductivos como la espermatogénesis y el desarrollo placentario y embrionario.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Este análisis de la literatura permitió valorar que los cambios estructurales, genéticos y epigenéticos que ocurren durante la formación del gameto masculino, pueden tener repercusiones en el desarrollo embrionario, principalmente en la formación de tejidos extraembrionarios como la placenta.</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Las alteraciones en los mecanismos moleculares implicados en el proceso de metilación del ADN durante la espermatogénesis, pueden generar errores en el patrón normal de expresión requerido para el adecuado desarrollo de los componentes feto-placentarios.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Genomic imprinting is the epigenetic change that occurred differentially in the specific genes in spermatozoa and oocyte according to their paternal or maternal origin, thus allowing a monoallelic expression. This review is a critical analysis of the published information relating to the role of the male imprinting on the successful reproduction.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We performed a literature search on some of the components that regulate the male genomic imprinting and the possible role on reproductive events such as spermatogenesis, and placental and embryo development.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The literature analysis allowed us to appreciate structural, genetic and epigenetic changes occurring during the formation of the male gamete that could have an impact on embryo development, mainly in the formation of extraembryonic tissues as the placenta.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Alterations in the molecular mechanisms involved in the sperm DNA methylation during the spermatogenesis, could induce alterations in the normal pattern of expression required in the fetal-placental components development.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:59 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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Influencia de la impronta genómica masculina en la reproducción
Influence of the Male Genomic Imprinting on the Reproduction
G.C. Vasco1
, A.M. Gil Villa, C. Piedrahita Ochoa, W. Cardona Maya, A. Cadavid Jaramillo
Autor para correspondencia
cadavida@une.net.co
reproduccion@medicina.udea.edu.co
Correspondencia autor: Dra. A. Cadavid Jaramillo Grupo Reproducción Sede de Investigación Universitaria (SIU) Universidad de Antioquia Medellín, Colombia, Sur América, A.A.1226. Tel: (57-4)-2196685 Fax: (57-4)-2196470
reproduccion@medicina.udea.edu.co
Correspondencia autor: Dra. A. Cadavid Jaramillo Grupo Reproducción Sede de Investigación Universitaria (SIU) Universidad de Antioquia Medellín, Colombia, Sur América, A.A.1226. Tel: (57-4)-2196685 Fax: (57-4)-2196470
Grupo Reproducción. Sede de Investigación Universitaria (SIU). Universidad de Antioquia. Medellín, Colombia