Compartir
array:24 [ "pii" => "S0210480609741269" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74126-9" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74126" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Urol Esp. 2009;33:209-13" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1653 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 763 "PDF" => 883 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480609741270" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74127-0" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74127" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Urol Esp. 2009;33:214" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1120 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 544 "PDF" => 567 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Ruptura renal tras caída accidental" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "214" ] ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rosa M. García Fanjul" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Rosa M." "apellidos" => "García Fanjul" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609741270?idApp=UINPBA00004N" "url" => "/02104806/0000003300000002/v1_201304251922/S0210480609741270/v1_201304251922/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480609741257" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74125-7" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74125" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Urol Esp. 2009;33:205-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1905 "formatos" => array:3 [ "EPUB" => 8 "HTML" => 1041 "PDF" => 856 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Mucocele apendicular confundido con quiste de uraco infectado: un diagnóstico diferencial a tener en cuenta" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "205" "paginaFinal" => "208" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Appendiceal mucocele misdiagnosed with infected urachal cyst: a differential diagnosis to keep in mind" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Daniel Pérez Fentes, Melissa Cortegoso González, Ana Puñal Pereira, Antonio Cimadevila García, Serafín Novás Castro, Miguel Blanco Parra" "autores" => array:6 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Daniel Pérez Fentes" ] 1 => array:2 [ "nombre" => "Melissa" "apellidos" => "Cortegoso González" ] 2 => array:2 [ "nombre" => "Ana" "apellidos" => "Puñal Pereira" ] 3 => array:2 [ "nombre" => "Antonio" "apellidos" => "Cimadevila García" ] 4 => array:2 [ "nombre" => "Serafín" "apellidos" => "Novás Castro" ] 5 => array:2 [ "nombre" => "Miguel" "apellidos" => "Blanco Parra" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609741257?idApp=UINPBA00004N" "url" => "/02104806/0000003300000002/v1_201304251922/S0210480609741257/v1_201304251922/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Metástasis cutáneas de un carcinoma transicional vesical productor de β-HCG" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "209" "paginaFinal" => "213" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Miguel Pascual Samaniego, Manuel A. Ruiz Serrano, Mª Ángeles González Núñez, Inmaculada Bravo Fernández, Juan A. Ramos Martín, Antonio García González" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Miguel" "apellidos" => "Pascual Samaniego" "email" => array:1 [ 0 => "mpaski10@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "Manuel A." "apellidos" => "Ruiz Serrano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Mª" "apellidos" => "Ángeles González Núñez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Inmaculada" "apellidos" => "Bravo Fernández" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] 4 => array:3 [ "nombre" => "Juan A." "apellidos" => "Ramos Martín" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "Antonio" "apellidos" => "García González" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Anatomía Patológica. Hospital San Pedro de Alcántara. Cáceres, España" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Urología. Servicio de Anatomía Patológica. Hospital San Pedro de Alcántara. Cáceres, España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. Miguel Pascual Samaniego Servicio de Urología. Hospital Universitario de Valladolid Avda. Ramón y Cajal, 3 - 47005 Valladolid Tel.: 983 420 000 Extensión 226" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Cutaneous metastases from transitional cell carcinoma of the bladder producing β-HCG" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-05-31" "fechaAceptado" => "2007-06-30" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88856" "palabras" => array:3 [ 0 => "Metástasis cutánea" 1 => "Carcinoma transicional vesical" 2 => "Beta-gonadotropina coriónica humana" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec88855" "palabras" => array:3 [ 0 => "Cutaneous metastases" 1 => "Transitional bladder cancer" 2 => "Beta-human chorionic gonadotropin" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A pesar de la alta incidencia de carcinoma transicional vesical, la aparición de metástasis cutáneas es infrecuente, más aún como primera manifestación de diseminación metastásica, asociándose a una pobre supervivencia.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La producción ectópica de beta-gonadotropina coriónica humana (β-HCG) ocurre en un 35% de los carcinomas transicionales vesicales y se ha correlacionado con tumores de alto grado, estadios avanzados, enfermedad metastásica, falta de respuesta a la radioterapia y pobre supervivencia, en virtud de su efecto regulador del crecimiento tumoral por un probable efecto antagonista sobre receptores de la cascada apoptótica. Presentamos el caso de una paciente de 36 años con carcinoma transicional de vejiga productor de β-HCG que presentó dos metástasis cutáneas como primer signo de enfermedad a distancia. Ambas circunstancias asociadas de forma excepcional identificaron un comportamiento muy agresivo del tumor y su mal pronóstico, desarrollando a corto plazo un estallido metastático a múltiples niveles incluyendo una metástasis pericárdica.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In spite of the high incidence of transitional cell carcinoma, cutaneous metastases are infrequent, especially when they are the first sign of metastatic spread, with a low survival rate.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Thirty five per cent of transitional cell carcinoma of the bladder have ectopic beta- human chorionic gonadotropin (β-HCG) production. It has been related with high grade tumors, advanced stage, metastatic disease, radioresistent tumors and low survival rate because of its effect as a growth modulator with a probably antagonist action in the apoptotic cascade. We present a thirty six years old woman affected by a transitional cell carcinoma of the bladder producing β-HCG that showed two cutaneous metastases as first sign of metastatic disease. The exceptional coincidence of these two circumstances announced a very aggressive tumor behaviour and bad prognostic, with a quickly multiple metastatic dissemination including a pericardic metastases.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carcinomas with trophoblastic differentiation and secretion of chorionic gonadotrophins" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Civantos" 1 => "A.M. Rywlin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Cancer" "fecha" => "1972" "volumen" => "29" "numero" => "3" "paginaInicial" => "789" "paginaFinal" => "798" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4334242" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Human chorionic gonadotropin expression by bladder cancers: biology and clinical potential" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.K. Iles" 1 => "T. Chard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "1991" "volumen" => "145" "numero" => "3" "paginaInicial" => "453" "paginaFinal" => "458" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1705292" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Beta human chorionic gonadotrophin in serum and urine. A marker for metastatic urothelial cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.K. Iles" 1 => "B.J. Jenkins" 2 => "R.T. Oliver" 3 => "J.P. Blandy" 4 => "T. Chard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Urol" "fecha" => "1989" "volumen" => "64" "numero" => "3" "paginaInicial" => "241" "paginaFinal" => "244" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2478247" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of β-human chorionic gonadotrophin on the in vitro growth of bladder cancer cell lines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.J. Guillot" 1 => "R.K. Iles" 2 => "T. Chard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Cancer" "fecha" => "1996" "volumen" => "73" "numero" => "3" "paginaInicial" => "323" "paginaFinal" => "326" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8562337" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The increase in bladder carcinoma cell population induced by the free beta subunit of human chorionic gonadotrophin is a result of an anti-apoptosis effect and not cell proliferation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.A. Butler" 1 => "M.S. Ikram" 2 => "S. Mathieu" 3 => "R.K. Iles" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1054/bjoc.2000.1177" "Revista" => array:7 [ "tituloSerie" => "Br J Cancer" "fecha" => "2000" "volumen" => "82" "numero" => "9" "paginaInicial" => "1553" "paginaFinal" => "1556" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10789723" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Human chorionic gonadotropin, neuron specific enolase and deoxyribonucleic acid flow cytometry in patients with high grade bladder carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A.B. Jacobsen" 1 => "J.M. Nesland" 2 => "S.D. Fosså" 3 => "E.O. Pettersen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "1990" "volumen" => "143" "numero" => "4" "paginaInicial" => "706" "paginaFinal" => "709" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2313795" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ectopic hCGbeta expression by epithelial cancer: malignant behaviour, metastasis and inhibition of tumor cell apoptosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.K. Iles" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Mol Cell Endocrinol" "fecha" => "2007" "volumen" => "2" "numero" => "260-262" "paginaInicial" => "264" "paginaFinal" => "270" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Urinary concentration of human chorionic gona - dotrophin and its fragments as a prognostic marker in bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.K. Iles" 1 => "R. Persad" 2 => "M. Trivedi" 3 => "K.B. Sharma" 4 => "A. Dickinson" 5 => "P. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Urol" "fecha" => "1996" "volumen" => "77" "numero" => "1" "paginaInicial" => "61" "paginaFinal" => "69" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8653319" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Production of trophoblastic hormones by transitional cell carcinoma of the bladder: association to tumor stage and grade" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Dirnhofer" 1 => "P. Koessler" 2 => "C. Ensinger" 3 => "H. Feichtinger" 4 => "S. Maders- bacher" 5 => "P. Berger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Hum Pathol" "fecha" => "1998" "volumen" => "29" "numero" => "4" "paginaInicial" => "377" "paginaFinal" => "382" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9563788" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glycoprotein hormones: structure and function" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.G. Pierce" 1 => "T.F. Parsons" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.bi.50.070181.002341" "Revista" => array:6 [ "tituloSerie" => "Annu Rev Biochem" "fecha" => "1981" "volumen" => "50" "paginaInicial" => "465" "paginaFinal" => "495" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6267989" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Crystal structure of human chorionic gonadotropin" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.J. Lapthorn" 1 => "D.C. Harris" 2 => "A. Littlejohn" 3 => "J.W. Lustbader" 4 => "R.E. Canfield" 5 => "K.J. Machin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "1994" "volumen" => "9" "numero" => "369(6480" "paginaInicial" => "455" "paginaFinal" => "461" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The probable origin of an anemone cell tumor: metastatic transitional cell carcinoma producing HCG" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.P. Wirt" 1 => "R.B. Nagle" 2 => "H.M. Gustafson" 3 => "P.J. Philpott" 4 => "N.A. Kuivinen" 5 => "M. Schuchardt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Ultrastruct Pathol" "fecha" => "1984" "volumen" => "7" "numero" => "4" "paginaInicial" => "277" "paginaFinal" => "288" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6537094" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous metastases from genitourinary malignancies" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T.J. Mueller" 1 => "H. Wu" 2 => "R.E. Greenberg" 3 => "G. Hudes" 4 => "N. Topham" 5 => "S.R. Lessin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.urology.2004.01.014" "Revista" => array:7 [ "tituloSerie" => "Urology" "fecha" => "2004" "volumen" => "63" "numero" => "6" "paginaInicial" => "1021" "paginaFinal" => "1026" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15183939" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cystic cutaneous metastases from transitional cell carcinoma of the bladder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I. Eardley" 1 => "J. Abercrombie" 2 => "B.J. Wright" 3 => "W.F. Hendry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J R Soc Med" "fecha" => "1987" "volumen" => "80" "numero" => "5" "paginaInicial" => "314" "paginaFinal" => "315" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3612665" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impact of surgical resection of bladder cancer metastases refractory to systemic therapy on performance score: a phase II trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Otto" 1 => "S. Krege" 2 => "J. Suhr" 3 => "H. Rubben" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Urology" "fecha" => "2001" "volumen" => "57" "numero" => "1" "paginaInicial" => "55" "paginaFinal" => "59" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11164143" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/02104806/0000003300000002/v1_201304251922/S0210480609741269/v1_201304251922/es/main.assets" "Apartado" => array:4 [ "identificador" => "6431" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Nota clínica" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/02104806/0000003300000002/v1_201304251922/S0210480609741269/v1_201304251922/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609741269?idApp=UINPBA00004N" "pdfAlternativo" => array:1 [ 0 => array:3 [ "idioma" => "en" "documentoPdf" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/file/02104806/addon/S0210480609741269/S300/en/292v33n02a13143333pdf001_2.pdf" "portada" => "292v33n02a13143333pdf001_2.png" ] ] ]
