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array:24 [ "pii" => "S0210480609728712" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)72871-2" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "72871" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:853-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4412 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 3371 "PDF" => 1034 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480609728724" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)72872-4" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "72872" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:860-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2754 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 1986 "PDF" => 762 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original – Cáncer de próstata</span>" "titulo" => "Prevalencia de alteración en las pruebas de coagulación en pacientes sometidos a biopsia transrectal de próstata" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "860" "paginaFinal" => "864" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prevalence of abnormal coagulation tests in patients who undergo transrectal biopsy of the prostate" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Herney Andrés García, Carlos Gonzalo Estrada, Jorge Carbonell" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Herney Andrés" "apellidos" => "García" ] 1 => array:2 [ "nombre" => "Carlos Gonzalo" "apellidos" => "Estrada" ] 2 => array:2 [ "nombre" => "Jorge" "apellidos" => "Carbonell" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609728724?idApp=UINPBA00004N" "url" => "/02104806/0000003300000008/v2_201304261001/S0210480609728724/v2_201304261001/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480609728700" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)72870-0" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "72870" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:844-52" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3521 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 2743 "PDF" => 769 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original – Cáncer de próstata</span>" "titulo" => "Valor de la PET en la recurrencia del cáncer de próstata con PSA < 5 ng/ml" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "844" "paginaFinal" => "852" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Usefulness of PET scans in diagnosing recurrent prostate cancer. Prostate with PSA level < 5<span class="elsevierStyleHsp" style=""></span>ng/ml" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Jorge Rioja Zuazu, Macarena Rodríguez, Aníbal Rincón Mayans, Abel Saiz Sansi, Juan Javier Zudaire Bergera, Rafael Martínez-Monge, José Ángel Richter, José María Berián Polo" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Jorge Rioja" "apellidos" => "Zuazu" ] 1 => array:2 [ "nombre" => "Macarena" "apellidos" => "Rodríguez" ] 2 => array:2 [ "nombre" => "Aníbal Rincón" "apellidos" => "Mayans" ] 3 => array:2 [ "nombre" => "Abel Saiz" "apellidos" => "Sansi" ] 4 => array:2 [ "nombre" => "Juan Javier Zudaire" "apellidos" => "Bergera" ] 5 => array:2 [ "nombre" => "Rafael" "apellidos" => "Martínez-Monge" ] 6 => array:2 [ "nombre" => "José Ángel" "apellidos" => "Richter" ] 7 => array:2 [ "nombre" => "José María Berián" "apellidos" => "Polo" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609728700?idApp=UINPBA00004N" "url" => "/02104806/0000003300000008/v2_201304261001/S0210480609728700/v2_201304261001/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original – Cáncer de próstata</span>" "titulo" => "Profilaxis antibiótica en la biopsia transrectal de próstata" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "853" "paginaFinal" => "859" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Daniel Muñoz Vélez, Antoni Vicens Vicens, Mariano Ozonas Moragues" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Daniel Muñoz" "apellidos" => "Vélez" "email" => array:1 [ 0 => "dr.munoz.velez@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "Antoni Vicens" "apellidos" => "Vicens" ] 2 => array:2 [ "nombre" => "Mariano Ozonas" "apellidos" => "Moragues" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Urología, Hospital Universitario Son Dureta, Palma de Mallorca, España" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Antibiotic prophylaxis in transrectal prostate biopsy" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-12-08" "fechaAceptado" => "2009-05-07" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec89426" "palabras" => array:4 [ 0 => "Próstata" 1 => "Biopsia" 2 => "Profilaxis" 3 => "Infección urinaria" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec89425" "palabras" => array:4 [ 0 => "Prostate" 1 => "Biopsy" 2 => "Prophylaxis" 3 => "Urinary infection" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p class="elsevierStyleSimplePara elsevierViewall">La biopsia transrectal de próstata ecodirigida es una técnica segura pero no exenta de complicaciones; las más graves son las infecciones urinarias y sus consecuencias. La profilaxis antibiótica pretende reducir esas complicaciones; sin embargo, no existe un protocolo establecido y hay notables diferencias entre los centros que llevan a cabo esta técnica. El objetivo del presente trabajo consiste en revisar diferentes aspectos de los protocolos de profilaxis antibiótica recogidos en la literatura científica.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se revisaron artículos indexados, publicados en inglés o español, recogidos en bases bibliográficas.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En 5 trabajos que compararon la profilaxis con el placebo el porcentaje de bacteriuria y complicaciones infecciosas fue menor en los grupos con profilaxis. El microorganismo causante en la mayoría de los casos fue <span class="elsevierStyleItalic">Escherichia coli</span>. Los antibióticos más empleados son las quinolonas por vía oral. En 3 trabajos que emplearon profilaxis oral o parenteral no hubo diferencias entre ambos grupos. Otros 3 artículos que compararon la pauta corta y la monodosis no observaron mayor beneficio con la pauta corta.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Administrar profilaxis es más ventajoso que no hacerlo. El momento para iniciar la profilaxis dependerá de la biodisponibilidad del fármaco y de la vía elegida. El antibiótico empleado preferiblemente se administrará por vía oral, en monodosis o pauta corta, teniendo en cuenta las sensibilidades de los microorganismos prevalentes. Son necesarios más estudios para determinar el papel de los enemas en la reducción de las complicaciones infecciosas.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Transrectal ultrasound-guided needle biopsy of the prostate is a safe technique, but it is not complication-free, and its most serious complications are genitourinary infections (GUI) and the conditions they cause. The purpose of antibiotic prophylaxis is to reduce this GUI incidence rate. However, no established guidelines exist and there are significant differences among centres where this procedure is performed. The objective of the present report is to review antibiotic prophylaxis protocols described in the literature.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We reviewed indexed articles published in English or Spanish and accessible through literature databases.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Five articles comparing antibiotic prophylaxis with a placebo observe lower bacteriuria and infectious complications percentage rates in the group receiving prophylaxis. In most cases, <span class="elsevierStyleItalic">E. coli</span> is the microorganism responsible for infection. Oral quinolones are the most commonly prescribed prophylactic antibiotics. Three studies of oral vs. parenteral prophylaxis found no differences between the two groups. Three other articles comparing short term and single-dose prophylaxis found no differences between the two groups.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Administering prophylactic antibiotics is more advantageous than not doing so. The moment for beginning prophylaxis depends on the antibiotic's bioavailability and how it is administered. The chosen antibiotic will preferably be administered orally as a single dose or short term course, according to the sensitivities of prevalent microorganisms. More studies are needed to determine what role pre-biopsy enemas play in reducing infectious complications.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate for the detection of prostate cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.A. Levine" 1 => "M. Ittman" 2 => "J. Melamed" 3 => "H. Lepor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Urol" "fecha" => "1998" "volumen" => "159" "paginaInicial" => "471" "paginaFinal" => "475" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9649265" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." 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Grabe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ijantimicag.2003.09.005" "Revista" => array:7 [ "tituloSerie" => "Int J Antimicrob Agents" "fecha" => "2004" "volumen" => "23" "numero" => "Suppl 1" "paginaInicial" => "S17" "paginaFinal" => "S23" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15037324" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevention of urinary tract infection and sepsis following transrectal prostatic biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E.D. Crawford" 1 => "A.L. Haynes Jr" 2 => "M.W. Story" 3 => "T.A. 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of prophylactic antimicrobial regimens in preventing infectious complications after transrectal biopsy of the prostate" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.D. Melekos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int Urol Nephrol" "fecha" => "1990" "volumen" => "22" "paginaInicial" => "257" "paginaFinal" => "262" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2210982" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Single-dose oral ciprofloxacin versus placebo for prophylaxis during transrectal prostate biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D.A. Kapoor" 1 => "I.W. Klimberg" 2 => "G.H. Malek" 3 => "J.D. Wegenke" 4 => "C.E. Cox" 5 => "A.L. Patterson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Urology" "fecha" => "1998" "volumen" => "52" "paginaInicial" => "552" "paginaFinal" => "558" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9763070" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Aron" 1 => "T.P. Rajeev" 2 => "N.P. Gupta" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "BJU Int" "fecha" => "2000" "volumen" => "85" "paginaInicial" => "682" "paginaFinal" => "685" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10759665" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Puig" 1 => "A. Darnell" 2 => "P. Bermúdez" 3 => "A. Malet" 4 => "G. Serrate" 5 => "M. Baré" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00330-005-0076-2" "Revista" => array:6 [ "tituloSerie" => "Eur Radiol" "fecha" => "2006" "volumen" => "16" "paginaInicial" => "939" "paginaFinal" => "943" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16391904" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antibiotic prophylaxis in urologic procedures: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A.M. Bootsma" 1 => "M.P. Laguna Pes" 2 => "S.E. Geerlings" 3 => "A. Goossens" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eururo.2008.03.033" "Revista" => array:6 [ "tituloSerie" => "Eur Urol" "fecha" => "2008" "volumen" => "54" "paginaInicial" => "1270" "paginaFinal" => "1286" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18423974" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Morbidity of ultrasound-guided transrectal core biopsy of the prostate without prophylactic antibiotic therapy. A prospective study in 415 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.L. Enlund" 1 => "E. Varenhorst" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Urol" "fecha" => "1997" "volumen" => "79" "paginaInicial" => "777" "paginaFinal" => "780" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9158518" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Infection after transrectal core biopsies of the prostate –risk factors and antibiotic prophylaxis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Aus" 1 => "G. Ahlgren" 2 => "S. Bergdahl" 3 => "J. Hugosson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "BJU Int" "fecha" => "1996" "volumen" => "77" "paginaInicial" => "851" "paginaFinal" => "855" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." 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