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Carcinoma transicional primario de ductus prostáticos
J.A. Queipo zaragozáa,1, A. Budía albaa, M. Pérez ebrí*, C.D. Vera donosoa, F. Vera semperea, J.F. Jiménez cruza
* Servicio de Anatomía Patológica. Hospital Universitario “La Fe”.Valencia
a Servicio de Urología. Hospital Universitario “La Fe”.Valencia
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El carcinoma transicional primario de pr&#243;stata es un tumor muy poco frecuente&#44; que tiene su origen en las c&#233;lulas epiteliales transicionales de los ductos intraprost&#225;ticos periuretrales&#46; De 829 casos de pacientes con diagn&#243;stico de carcinoma de pr&#243;stata&#44; hemos encontrado 17 con la variedad transicional&#46; De ellos&#44; 8 ten&#237;an un carcinoma puro de c&#233;lulas transicionales y 9 correspond&#237;an a formas mixtas de adenocarcinoma acinar y carcinoma ductal de c&#233;lulas transicionales&#46; En todos ellos se descart&#243; el origen vesical de la tumoraci&#243;n&#46; Nuestro objetivo es el estudio retrospectivo del comportamiento cl&#237;nico del carcinoma transicional de pr&#243;stata&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Encontramos pocas diferencias en comparaci&#243;n con los carcinomas acinares cuando evaluamos la edad&#44; los s&#237;ntomas&#44; los hallazgos f&#237;sicos y el diagn&#243;stico por imagen&#46; La presentaci&#243;n cl&#237;nica&#44; el tacto rectal&#44; el PSA&#44; la diseminaci&#243;n metast&#225;sica y la existencia de uropat&#237;a obstructiva supravesical al inicio del diagn&#243;stico fueron otras caracter&#237;sticas cl&#237;nicas a estudio&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El tratamiento aplicado ha sido heterog&#233;neo siendo el m&#225;s utilizado la radioterapia&#46; Respecto a la supervivencia&#44; actualmente se han producido 11 exitus&#44; con una supervivencia media de 26&#44;6 meses &#40;4-60 meses&#41;&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El comportamiento biol&#243;gico de este tumor se caracteriza por ser hormonorresistente&#44; agresivo y de peor pron&#243;stico que las formas acinares&#46; Su diagn&#243;stico precoz y la cirug&#237;a radical es lo &#250;nico que podr&#237;a aumentar la expectativa de vida de estos pacientes&#46;</p>"
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        "resumen" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Primary prostate transitional cell carcinoma is a very rare tumour originating in the transitional epithelial cells of the intraprostate periurethral ductus&#46; Only 17 of 829 patients diagnosed with prostate carcinoma were found to have the transitional cell variety&#46; Eight &#40;8&#41; of those had pure transitional cell carcinoma and 9 a mixed presentation of acinar adenocarcinoma and transitional cell ductal carcinoma&#46; Bladder origin of the tumour was ruled out in all cases&#46; We report a retrospective study on the clinical behaviour of prostate transitional cell carcinoma&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Compared to acinar carcinomas&#44; few differences were found when age&#44; symptoms&#44; physical findings and imaging diagnosis were evaluated&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Clinical presentation&#44; DRE&#44; PSA&#44; metastatic spread and presence of supravesical obstructive uropathy where also studied to establish a diagnosis&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Radiotherapy was the most frequently used therapeutical approach&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Mean survival is 26&#46;6 months &#40;4-60 months&#41; and there has been 11 death up to now&#46;</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Compared to acinar forms&#44; this tumour shows a hormone-resistant&#44; aggressive biological behaviour with poor prognosis&#46; Early diagnosis and radical surgery are the only options available to increase life expectancy for these patients&#46;</p>"
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Información del artículo
ISSN: 02104806
Idioma original: Español
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es en pt

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Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos