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Evaluación económica del tratamiento médico de la hiperplasia benigna de próstata (HBP) en España en atención especializada. Aplicación al costeefectividad de dos fármacos habitualmente utilizados en su tratamiento
Economic Evaluation Of Medical Treatment Of Benign Prostatic Hyperplasia (Bph) In The Specialised Care Setting In Spain. Application To The Cost-Effectiveness Of Two Drugs Frequently Used In Its Treatment
J. Carballido1,1
Autor para correspondencia
EricJohn.Slof@uab.es

Correspondencia autor: Dr. John Slof Departamento de Economía de la Empresa. Universidad Autónoma de Barcelona. Campus de la UAB 08193 Bellaterra (Barcelona). Tel.: 935 814 399; Fax.: 935 812 555
, J.L. Ruiz-Cerdá2, M. Unda3, V. Baena4, P. Campoy5, J. Manasanch6, J. Slof7
1 Servicio de Urología Hosp. Univ. Puerta de Hierro, Madrid
2 Servicio de Urología Hosp. Univ. La Fe, Valencia
3 Servicio de Urología Hosp. de Basurto, Bilbao
4 Servicio de Urología Hosp. Univ. Carlos Haya, Málaga
5 Servicio de Urología Hosp. Univ. Virgen del Rocío, Sevilla
6 Pierre Fabre Ibérica S.A., Barcelona
7 Departamento de Economía de la Empresa. Univ. Autónoma de Barcelona
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Llevar a cabo un estudio farmacoecon&#243;mico para conocer el coste medio del diagn&#243;stico y seguimiento de la HBP en Espa&#241;a en el &#225;mbito de la atenci&#243;n especializada desde la perspectiva del sistema p&#250;blico de salud&#44; considerando dos f&#225;rmacos frecuentemente utilizados en el entorno sanitario espa&#241;ol&#44; un alfabloqueante &#40;tamsulosina&#41; y el extracto lipidoester&#243;lico de Serenoa repens &#40;Permix&#243;n&#174;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se determinaron los costes sanitarios directos del diagn&#243;stico y tratamiento de la HBP para cada presentaci&#243;n cl&#237;nica seg&#250;n el valor del International Prostate Symptom Score &#40;IPSS&#41;&#58; leve&#44; moderada y grave&#46; Los datos sobre el consumo y los costes unitarios de los recursos sanitarios se recogieron mediante una encuesta semi-estructurada a expertos cl&#237;nicos&#46; La eficacia cl&#237;nica del tratamiento m&#233;dico fue obtenida del estudio cl&#237;nico PERMAL&#44; en el que se observ&#243; equivalencia terap&#233;utica entre ambos f&#225;rmacos&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El coste medio anual de pruebas diagn&#243;sticas y visitas m&#233;dicas de la HBP sintom&#225;tica seg&#250;n fuese leve&#44; moderada o grave fueron&#44; respectivamente&#44; 124&#44; 207 y 286 para pacientes tratados en atenci&#243;n especializada&#46; El coste medio anual del tratamiento m&#233;dico&#44; incluyendo la atenci&#243;n de los efectos adversos fue de 211 para Permix&#243;n&#174; y 346 para tamsulosina&#46;</p> <span class="elsevierStyleSectionTitle">Discusi&#243;n</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El coste de la atenci&#243;n m&#233;dica de la HBP es proporcional a la intensidad de la sintomatolog&#237;a&#46; El tratamiento farmacol&#243;gico constituye una parte significativa del coste de la enfermedad&#46; En base al modelo utilizado&#44; el tratamiento con Permix&#243;n&#174; es sensiblemente m&#225;s coste-efectivo que el tratamiento con tamsulosina&#44; representando un ahorro medio de 135 por paciente y a&#241;o&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To develop a pharmacoeconomic study in order to know the average cost of BPH diagnosis and follow-up in Spain in the Urology Department setting from the perspective of the public health system&#44; considering two frequently used drugs in the Spanish Healthcare environment&#44; an alpha-blocker &#40;tamsulosin&#41; and the lipido-sterolic extract of Serenoa repens &#40;Permixon&#174;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Direct healthcare costs of BPH diagnosis and treatment were determined for each clinical stage according to the International Prostate Symptom Score &#40;IPSS&#41;&#58; mild&#44; moderate and severe&#46; Data on the usage and unit costs of healthcare resources were obtained from a semi-structured interview with clinical experts&#46; The clinical efficacy of the medical treatments was obtained from the PERMAL clinical study&#44; where therapeutic equivalence between the two studied drugs was observed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">For patients treated in the Urology Department setting&#44; the average annual cost of diagnostic tests and medical visits related to mild&#44; moderate or severe BPH symptoms were&#44; respectively&#44; 124&#44; 207&#44; and 286&#46; The average annual cost of the drugs&#44; including adverse effects treatment&#44; was 211 for Permixon&#174; and 346 for tamsulosin&#46;</p> <span class="elsevierStyleSectionTitle">Discussion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Costs of medical care of BPH increases with symptom intensity&#46; Pharmacological treatment makes up a significant part of the disease&#8217;s cost&#46; According to the model used&#44; treatment with Permixon&#174; is considerably more cost-effective than with tamsulosin&#44; offering average yearly savings of 135 per patient&#46;</p>"
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                      "titulo" => "Epidemiology and natural history of benign prostatic hyperplasia"
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                          "autores" => array:1 [
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                        "tituloSerie" => "Urol Clin North Am"
                        "fecha" => "1995"
                        "volumen" => "22"
                        "numero" => "2"
                        "paginaInicial" => "247"
                        "paginaFinal" => "261"
                        "link" => array:1 [
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                    0 => array:2 [
                      "titulo" => "Prevalence of urinary symptoms and other urological conditions in Spanish men 50 years old or older"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;J&#46; Hunter"
                            1 => "A&#46; Berra-Unamuno"
                            2 => "A&#46; Martin-Gordo"
                          ]
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                    ]
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                        "tituloSerie" => "J Urol"
                        "fecha" => "1996"
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                        "numero" => "6"
                        "paginaInicial" => "1975"
                        "paginaFinal" => "1976"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8618300"
                            "web" => "Medline"
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;A&#46; Chicharro-Molero"
                            1 => "R&#46; Burgos-Rodriguez"
                            2 => "J&#46;J&#46; Sanchez-Cruz"
                            3 => "J&#46;M&#46; del Rosal-Samaniego"
                            4 => "P&#46; Rodero-Carcia"
                            5 => "J&#46;M&#46; Rodriguez-Vallejo"
                          ]
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                    ]
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                        "fecha" => "1998"
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                        "numero" => "3"
                        "paginaInicial" => "878"
                        "paginaFinal" => "882"
                        "link" => array:1 [
                          0 => array:2 [
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                        "link" => array:1 [
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                    ]
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                        "tituloSerie" => "Actas Urol Esp"
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                        "paginaInicial" => "841"
                        "paginaFinal" => "847"
                        "link" => array:1 [
                          0 => array:2 [
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                        "paginaFinal" => "306"
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Información del artículo
ISSN: 02104806
Idioma original: Español
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